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Research Letter
May 2018

Ultra-Widefield Angiography With Oral Fluorescein in Pediatric Patients With Retinal Disease

Author Affiliations
  • 1Pediatric Ophthalmology Division, Moorfields Eye Hospital Centre, Abu Dhabi, United Arab Emirates
  • 2Moorfields Eye Hospital Dubai, Dubai, United Arab Emirates
  • 3Vitreoretinal Division, Moorfields Eye Hospital Centre, Abu Dhabi, United Arab Emirates
JAMA Ophthalmol. 2018;136(5):593-594. doi:10.1001/jamaophthalmol.2018.0462

Ultra-widefield (UWF) imaging is one of the new technologies available to ophthalmologists. Current UWF imaging modalities can provide several options for posterior segment documentation and evaluation, including color and red-free photography, fluorescein angiography, and fundus autofluorescence.1 The use of UWF fundus fluorescein angiography (FFA), in particular, has contributed significantly to the detection of peripheral fundus disease in both adult and pediatric patients with retinal conditions.2 Similar to standard field retinal angiography, FFA involves intravenous injection of fluorescein, after which fundus images are obtained. An alternative to intravenous injection of fluorescein is oral fluorescein angiography. It is used in cases in which intravenous injection is difficult to perform or is refused by patients who have a fear of needles. Oral FFA has been successfully used with standard and widefield camera systems.3 Herein, we report our experience with UWF retinal angiography using oral fluorescein in pediatric patients.