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A 43-year-old woman had unilateral exophthalmos caused by primary orbital Ewing sarcoma. Specialized immunohistochemical stains, primarily MIC-2 (CD99), aided in the diagnosis of Ewing sarcoma. Twenty-two months after radiotherapy and multiagent chemotherapy, the patient remained tumor free. To our knowledge, this is the first reported case of orbital Ewing sarcoma to present in an adult beyond the fourth decade of life.
Choi RY, Lucarelli MJ, Imesch PD, Hafez GR, Albert DM, Dortzbach RK. Primary Orbital Ewing Sarcoma in a Middle-aged Woman. Arch Ophthalmol. 1999;117(4):535–537. doi:https://doi.org/10.1001/archopht.117.4.535
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