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Clinicopathologic Report
October 1999

Orbital Metastasis Due to Interval Lobular Carcinoma of the Breast: A Potential Mimic of Lymphoma

Author Affiliations

From the Dental Hospital, The Heath, Cardiff, Wales (Dr Wolstencroft); the Departments of Maxillofacial Surgery (Dr Hodder and Mr Sugar), Histopathology (Dr Griffiths), and Radiology (Dr Jones), Morriston Hospital, Swansea, Wales; and Singleton Hospital, Swansea (Dr Askill).



Arch Ophthalmol. 1999;117(10):1419-1421. doi:10.1001/archopht.117.10.1419

A 53-year-old woman had an orbital mass composed of a neoplastic small round cell infiltrate and no apparent extraorbital primary tumor. Although the initial diagnosis was primary orbital lymphoma, a combination of mucin histochemistry and immunohistochemical staining for cytokeratin and estrogen receptors led to the discovery of an impalpable lobular carcinoma of the breast. We discuss how detailed histopathological assessment can lead to beneficial therapy.