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Case Reports and Small Case Series
November 1999

Cardiac Metastasis of Choroidal Melanoma

Arch Ophthalmol. 1999;117(11):1558-1559. doi:

We report a rare occurrence of cardiac metastasis from uveal melanoma.

A 74-year-old woman had decreased vision in the left eye. On examination, she was found to have a pigmented choroidal lesion in the superior fundus that measured 11 × 11 mm at the base and 6.2 mm in height. The diagnosis was a medium-sized choroidal melanoma (Figure 1). The patient entered the Collaborative Ocular Melanoma Study and received sodium iodide I 125 brachytherapy in October 1987. Eight years and 9 months later, the patient complained of dizziness, was examined, and was found to have a left ventricular mass (Figure 2). She underwent an excisional biopsy, but died the following day of a ruptured myocardium. Microscopic examination of the excised tissue revealed pigmented cells invading the myocardium consistent with metastatic choroidal melanoma (Figure 3).