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Surgical Technique
April 2000

A Single-Suture Technique for Placement of the Ganciclovir Implant

Author Affiliations

From the Department of Ophthalmology, Northwestern University Medical School (Drs Jones and Weinberg) and Veterans Affairs Chicago Healthcare System, Lakeside Division (Dr Weinberg), Chicago, Ill. The authors have no proprietary interest in the materials or techniques described in this report.

Arch Ophthalmol. 2000;118(4):584-585. doi:10.1001/archopht.118.4.584

The ganciclovir implant is a surgically implanted sustained-release drug delivery system used for the treatment of cytomegalovirus retinitis. The device is suspended in the vitreous cavity through a pars plana incision. Previous reports of the surgical procedure have described securing the implant on 1 suture, tied with an external knot. The ends of this suture were left long to avoid sharp ends eroding through the conjunctiva. The wound was then closed with 1 or more additional sutures, with the ends tied and cut short. We describe a technique whereby the wound is closed and the implant secured with a single running suture. The advantages of this technique include efficiency and elimination of exposed knots. We have observed no complications attributable to this technique.