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Clinical Sciences
May 2003

Classification of Visual Field Abnormalities in the Ocular Hypertension Treatment Study

Author Affiliations

From the Visual Field Reading Center, Department of Ophthalmology, University of California–Davis (Dr Keltner and Mss Cello, Edwards, and Bandermann); Discoveries in Sight, Devers Eye Institute, Portland, Ore (Dr Johnson); and the Department of Ophthalmology and Visual Science, Washington University School of Medicine, St Louis, Mo (Drs Kass and Gordon). For a complete list of authors, refer to the Ocular Hypertension Treatment Study Web site:http://www.vrcc.wustl.edu.

Arch Ophthalmol. 2003;121(5):643-650. doi:10.1001/archopht.121.5.643
Abstract

Objectives  (1) To develop a classification system for visual field (VF) abnormalities, (2) to determine interreader and test-retest agreement, and (3) to determine the frequency of various VF defects in the Ocular Hypertension Treatment Study.

Methods  Follow-up VFs are performed every 6 months and are monitored for abnormality, indicated by a glaucoma hemifield test result or a corrected pattern SDoutside the normal limits. As of January 1, 2002, 1636patients had 2509 abnormal VFs. Three readers independently classified each hemifield using a classification system developed at the VF reading center. Asubset (50%) of the abnormal VFs was reread to evaluate test-retest reader agreement. A mean deviation was calculated separately for the hemifields as an index to the severity of VF loss.

Main Outcome Measures  A 97% interreader hemifield agreement.

Results  The average hemifield classification agreement (between any 2 of 3 readers) for 5018 hemifields was 97% and 88% for the 1266 abnormal VFs that were reread(agreement between the first and second classifications). Glaucomatous patterns of loss (partial arcuate, paracentral, and nasal step defects) composed the majority of VF defects.

Conclusion  The Ocular Hypertension Treatment Study classification system has high reproducibility and provides a possible nomenclature for characterizing VF defects.

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