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Clinicopathologic Reports, Case Reports, and Small Case Series
June 2003

Histopathological Analysis of the Cornea After Laser In Situ Keratomileusis

Arch Ophthalmol. 2003;121(6):896-898. doi:10.1001/archopht.121.6.896

We report a case of an intact laser in situ keratomileusis (LASIK) flap despite traumatic rupture of the eye 13 months postoperatively. An eye that had undergone a successful LASIK procedure was ruptured in an airplane crash 13 months postoperatively. The cornea developed blood staining. A keratoprosthesis was placed so the posterior pole of the eye could be evaluated and then was replaced with a donor corneal graft. The recipient cornea, which included the LASIK flap, was examined by histologic analysis. Despite major ocular trauma 13 months after LASIK, the flap was intact. Keratocytes were diminished in the flap. Blood staining was minimal in the flap but pronounced in the underlying corneal stroma.

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