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Clinicopathologic Reports, Case Reports, and Small Case Series
December 2003

Conjunctival Melanoma With a Positive Sentinel Lymph Node

Arch Ophthalmol. 2003;121(12):1779-1783. doi:10.1001/archopht.121.12.1779

Conjunctival melanoma is a rare tumor of the ocular surface, with an annual incidence of fewer than 5 cases per million residents of the United States and a 10-year mortality rate of about 30%.1-3 The standard management of conjunctival melanoma consists of local resection, with application of cryotherapy to the resection margins.4 There is currently no reliable method of predicting which patients will develop regional lymph node metastasis, although tumor thickness is associated with poorer prognosis and higher likelihood of metastatic disease.5 After resection of conjunctival tumors, patients are commonly observed clinically until overt clinical signs of metastasis develop. Once clinically detectable metastatic disease develops, the prognosis is poor.