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Clinicopathologic Reports, Case Reports, and Small Case Series
January 2004

Orbital Metastasis and Intraocular Invasion of Malignant Mixed Tumor(Carcinosarcoma) of the Parotid Gland in a Child

Author Affiliations
 

W. RICHARDGREENMD

Arch Ophthalmol. 2004;122(1):114-118. doi:10.1001/archopht.122.1.114

Malignant mixed tumor of the salivary glands is a rare neoplasm, andthe majority of these tumors arise from the parotid gland.1 Histopathologically,3 distinct variants of malignant mixed tumors are recognized, the most commonbeing carcinoma arising from a preexisting pleomorphic adenoma.1,2 Thesecond type is the metastasizing mixed tumor, which has benign-appearing epithelialand stromal components.1,2 Thetrue malignant mixed tumor or carcinosarcoma, an exceptionally rare tumor,is the third subtype and is composed of malignant epithelial and malignantmesenchymal elements.2,3

Less than 5% of all salivary gland neoplasms are seen in patients youngerthan 16 years and 13% of these tumors are solid, of which only 23% are malignant.4 The most common malignant salivary gland tumorin children is mucoepidermoid carcinoma, followed by rhabdomyosarcoma andacinic cell carcinoma.4 We herein describea highly unusual patient with a carcinosarcoma of the parotid gland that metastasizedto ipsilateral orbit and intraocular structures.

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