Customize your JAMA Network experience by selecting one or more topics from the list below.
Malignant mixed tumor of the salivary glands is a rare neoplasm, andthe majority of these tumors arise from the parotid gland.1 Histopathologically,3 distinct variants of malignant mixed tumors are recognized, the most commonbeing carcinoma arising from a preexisting pleomorphic adenoma.1,2 Thesecond type is the metastasizing mixed tumor, which has benign-appearing epithelialand stromal components.1,2 Thetrue malignant mixed tumor or carcinosarcoma, an exceptionally rare tumor,is the third subtype and is composed of malignant epithelial and malignantmesenchymal elements.2,3
Less than 5% of all salivary gland neoplasms are seen in patients youngerthan 16 years and 13% of these tumors are solid, of which only 23% are malignant.4 The most common malignant salivary gland tumorin children is mucoepidermoid carcinoma, followed by rhabdomyosarcoma andacinic cell carcinoma.4 We herein describea highly unusual patient with a carcinosarcoma of the parotid gland that metastasizedto ipsilateral orbit and intraocular structures.
Kiratli H, Soysal HG, Demir S. Orbital Metastasis and Intraocular Invasion of Malignant Mixed Tumor(Carcinosarcoma) of the Parotid Gland in a Child. Arch Ophthalmol. 2004;122(1):114–118. doi:https://doi.org/10.1001/archopht.122.1.114
Create a personal account or sign in to: