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Clinicopathologic Reports, Case Reports, and Small Case Series
June 2004

Bilateral Lacrimal Gland Involvement With Kimura Disease in an AfricanAmerican Male

Author Affiliations


Arch Ophthalmol. 2004;122(6):917-919. doi:10.1001/archopht.122.6.917

Kimura disease (KD) is an inflammatory condition that classically manifestsas painless subcutaneous nodules of the head and neck in young Asian males.1,2 Histologically, it is characterizedas lymphoid follicles with germinal centers, distinguished by an eosinophilicinfiltrate and varying degrees of fibrosis.2 Thismakes the diagnosis of KD challenging as these histological features may overlapthat of idiopathic orbital inflammation3 orangiolymphoid hyperplasia with eosinophilia (ALHE).1,2 Wediscuss a unique case of KD with bilateral orbital involvement in an AfricanAmerican male. Based on our English-language MEDLINE literature search, toour knowledge, this seems to be the first clearly documented case of KD withsimultaneous bilateral lacrimal gland involvement. This case is particularlyintriguing as it occurred in a non-Asian patient.