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Clinicopathologic Reports, Case Reports, and Small Case Series
October 2004

Pleomorphic Adenoma of the Lacrimal Gland in a Child After Treatmentof Acute Lymphoblastic Leukemia

Author Affiliations
 

W. RICHARDGREENMD

Arch Ophthalmol. 2004;122(10):1538-1540. doi:10.1001/archopht.122.10.1538

Among all orbital masses in children, tumors and related lesions ofthe lacrimal gland are very uncommon (1.8%-2.4%). Most of these prove to benongranulomatous or granulomatous chronic dacryoadenitis, with only a fewbeing neoplasms.1

Pleomorphic adenoma (benign mixed tumor) of the lacrimal gland (PALG)is a benign tumor that mostly arises in the orbital lobe. It is quite commonin adults but very rare in children. In published series of orbital massesin children by Shields et al1 and Kodsiet al,2 340 and 250 masses, respectively,included no case of PALG. We are aware of only 4 cases reported in childrenaged 14 years or younger and another 3 cases reported in adolescents, withthe first being reported in 1938 by Sanders3 andwith a 6-year-old boy as the youngest patient at the time of diagnosis.4 Mercado et al5 reportedthe case of a PALG in a 15-year-old girl. None of these cases had any historyof chemotherapy or radiotherapy for leukemia or any deficiency of the immunesystem.

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