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Alió JL, Mulet ME, Zapata LF, Vidal MT, De Rojas V, Javaloy J. Intracorneal Inlay Complicated by Intrastromal Epithelial Opacification. Arch Ophthalmol. 2004;122(10):1441–1446. doi:10.1001/archopht.122.10.1441
To report epithelial perilenticular opacity as a new complication ofintracorneal inlay implantation for the correction of hyperopia.
Prospective observational case series.
Eleven eyes of 7 patients underwent intracorneal inlay implantationfor the correction of hyperopia.
Intracorneal inlays were implanted onto the stromal bed by using a microkeratomecut to create an inferior hinged corneal flap.
Main Outcome Measures
Postoperative complication occurrence of intracorneal perilenticularopacity, microbiological laboratory analysis, histopathological analysis,and confocal microscopy study.
Of 11 implanted eyes, 5 showed diffuse perilenticular opacity of varyingintensity that was unresponsive to steroid use following intracorneal inlayimplantation. All patients had moderate to severe loss of best-corrected visualacuity. The inlays showed deposits at the edge and on the surface. Confocalmicroscopy in all eyes produced images compatible with the confocal morphologicfeatures of epithelial cells. Explantation of inlays was performed in 5 eyes.The histopathologic study showed the presence of epithelial cells, and microbiologicalanalysis and cultures were negative for bacteria, fungi, and mycobacteria.
Epithelial perilenticular opacity is a new and serious complicationin patients with intracorneal inlay implantation for the correction of hyperopia.
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