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Clinicopathologic Reports, Case Reports, and Small Case Series
June 2006

Adduction on Attempted Abduction: The Opposite of Synergistic Divergence

Arch Ophthalmol. 2006;124(6):918-920. doi:10.1001/archopht.124.6.918

Congenital fibrosis of the extraocular muscles (CFEOM) is a congenital ocular motility disorder that manifests as restrictive ophthalmoplegia with ptosis.1 Synergistic divergence (SD) is a deficit of adduction associated with simultaneous bilateral abduction on attempted gaze into the field of action of the affected medial rectus muscle.2 There has been no pathologic report of SD; however, magnetic resonance imaging showed that in 2 patients with CFEOM and SD, the oculomotor nerve was hypoplastic bilaterally and the abducens nerve was absent on the side exhibiting SD.3 To our knowledge, bilateral deficit of abduction associated with simultaneous bilateral adduction on attempted gaze into the field of action of the lateral rectus muscles, the counterpart of SD, has not been previously reported.