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Discrete lines of increased fundus autofluorescence (FAF) have recently been described in various retinal dystrophies.1,2It has been shown that these lines demarcate areas with impaired retinal sensitivity from those without and may constrict or expand in different retinal dystrophies over time.1,2Morphological changes corresponding to lines of increased FAF have not been described yet. Likewise, the mechanism underlying the abnormal accumulation of lipofuscin and increased FAF is unknown. In retinitis pigmentosa, abnormally increased FAF commonly forms a parafoveal ring or annulus. Recent optical coherence tomography (OCT) findings suggest that the band that represents the interface of the inner/outer segments of photoreceptors may be preserved within the ring.3
Fleckenstein M, Issa PC, Helb H, Schmitz-Valckenberg S, Scholl HPN, Holz FG. Correlation of Lines of Increased Autofluorescence in Macular Dystrophy and Pigmented Paravenous Retinochoroidal Atrophy by Optical Coherence Tomography. Arch Ophthalmol. 2008;126(10):1461–1463. doi:10.1001/archopht.126.10.1461
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