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April 11, 2011

Healthy Lifestyles Related to Subsequent Prevalence of Age-Related Macular Degeneration

Author Affiliations

Author Affiliations: Departments of Ophthalmology and Visual Sciences (Drs Mares, Voland, Moeller, and Blodi and Ms Sondel), Family Medicine (Dr LaRowe), Statistics and Biostatistics (Dr Chappell), and Obstetrics and Gynecology, Center for Women's Health Research (Dr Sarto), University of Wisconsin, Madison; Department of Social and Preventive Medicine, University at Buffalo, Buffalo, New York (Dr Millen); Casey Eye Institute, Oregon Health Sciences University, Portland (Dr Klein); Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington (Dr Tinker); Department of Family and Community Medicine, University of Arizona College of Medicine, Tucson (Dr Ritenbaugh); Center for Retina and Macular Disease, Winter Haven, Florida (Dr Gehrs); Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts (Dr Johnson); Department of Nutritional Sciences, University of Texas at Austin (Dr Snodderly); and Department of Epidemiology, University of Iowa, Iowa City (Dr Wallace).



Arch Ophthalmol. 2011;129(4):470-480. doi:10.1001/archophthalmol.2010.314

The macula of the human eye progressively degenerates with age, more quickly in some people than in others. This can lead to advanced age-related macular degeneration (AMD), which involves the loss of photoreceptors in the macula of the eye. Treatment for advanced AMD is of limited effectiveness, is costly,1 and will become even more costly as the number of older Americans increases in the coming decades.2 Moreover, it profoundly limits the ability of older adults to function independently. The loss of central vision associated with advanced AMD diminishes the ability to see and recognize other people's faces and to read fine print such as that in newspapers and on pill bottles and food packages.