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Article
March 1940

SYNDROME OF NEUROMYELITIS OPTICA

Arch Ophthalmol. 1940;23(3):577-583. doi:10.1001/archopht.1940.00860130643013
Abstract

So complex is the nervous system and so manifold its functions that one and the same etiologic agent may produce many different syndromes by the pure chance of the site and the tempo of involvement. A disease affecting the upper or lower lobe of the lung, some portion of the liver or the right or left kidney may give similar symptoms and is considered under one designation. However, if there is a virus infection in the nervous system and it happens to attack the second cranial nerve, it may be called "papillitis" ; if the vestibular portion of the eighth nerve is involved, one reads of "epidemic vertigo"; if the seventh nerve is invaded, there is facial paralysis.

As the possible combinations of involvement of the brain, cranial nerves, brain stem and spinal cord are numerous, so too are the designations or the syndromes.1 These syndromes have a certain historical

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