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February 2020 - January 1929

Decade

Year

Issue

March 2020, Vol 138, No. 3, Pages 235-319

Original Investigation

Association of Visit Adherence and Visual Acuity in Patients With Neovascular Age-Related Macular Degeneration: Secondary Analysis of the Comparison of Age-Related Macular Degeneration Treatment Trial

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):237-242. doi:10.1001/jamaophthalmol.2019.4577

This secondary analysis of the Comparison of Age-Related Macular Degeneration Treatment Trial randomized clinical trial assesses the association of patient adherence and visual acuity in individuals with neovascular age-related macular degeneration.

Efficacy of a Treat-and-Extend Regimen With Ranibizumab in Patients With Neovascular Age-Related Macular Disease: A Randomized Clinical Trial

Abstract Full Text
open access has active quiz
JAMA Ophthalmol. 2020;138(3):244-250. doi:10.1001/jamaophthalmol.2019.5540

This noninferiority randomized clinical trial evaluates once-monthly vs a treat-and-extend regimen of ranibizumab injections in patients with age-related neovascular macular degeneration.

Cost-effectiveness of Intravitreal Ranibizumab With Verteporfin Photodynamic Therapy Compared With Ranibizumab Monotherapy for Patients With Polypoidal Choroidal Vasculopathy

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):251-259. doi:10.1001/jamaophthalmol.2019.5628

This economic evaluation assesses the incremental cost-effectiveness of combination intravitreal ranibizumab and verteporfin photodynamic therapy compared with ranibizumab monotherapy in patients with polypoidal choroidal vasculopathy.

Accuracy of The Cancer Genome Atlas Classification vs American Joint Committee on Cancer Classification for Prediction of Metastasis in Patients With Uveal Melanoma

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):260-267. doi:10.1001/jamaophthalmol.2019.5710

This cohort study compares the accuracy of The Cancer Genome Atlas classification with the American Joint Committee on Cancer classification for predicting uveal melanoma–related metastasis.

Characteristics of Open Globe Injuries in the United States From 2006 to 2014

Abstract Full Text
has active quiz has audio
JAMA Ophthalmol. 2020;138(3):268-275. doi:10.1001/jamaophthalmol.2019.5823

This cross-sectional study of US nationwide emergency department data examines the incidence, common injury mechanisms, and economic burden of ocular trauma open globe injuries in the United States.

Characteristics of Eyes With Good Visual Acuity at 5 Years After Initiation of Treatment for Age-Related Macular Degeneration but Not Receiving Treatment From Years 3 to 5: Post Hoc Analysis of the CATT Randomized Clinical Trial

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):276-284. doi:10.1001/jamaophthalmol.2019.5831

This case-control study examines the baseline data and 5-year outcomes of participants in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) who retained good vision despite receiving no therapy for 3 years after release from the 2-year CATT treatment protocol.

Visual Field Changes Over 5 Years in Patients Treated With Panretinal Photocoagulation or Ranibizumab for Proliferative Diabetic Retinopathy

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):285-293. doi:10.1001/jamaophthalmol.2019.5939

This post hoc analysis of a randomized clinical trial evaluates change in visual field throughout 5 years among eyes treated with panretinal photocoagulation injectable ranibizumab for proliferative diabetic retinopathy.

Genetic Heritability of Pigmentary Glaucoma and Associations With Other Eye Phenotypes

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):294-299. doi:10.1001/jamaophthalmol.2019.5961

This genome-wide association study calculates the single-nucleotide polymorphism heritability of pigmentary glaucoma and identifies genetic associations with the disease.

Brief Report

Ciliary Body Mass as a Feature of Ocular Sarcoidosis

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):300-304. doi:10.1001/jamaophthalmol.2019.5704

This case series describes diffuse or segmental ciliary body mass in 3 individuals, in whom it was a clinical sign and tissue source for biopsy in the diagnosis of ocular sarcoidosis.

Vascularization and Reperfusion of Autologous Retinal Transplant for Giant Macular Holes

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):305-309. doi:10.1001/jamaophthalmol.2019.5733

This case series examines vascularization and reperfusion of autologous retinal graft after transplant for giant macular holes demonstrated by multimodal imaging.

Invited Commentary

Association Between Visit Adherence and Visual Acuity in Neovascular Age-Related Macular Degeneration

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):242-243. doi:10.1001/jamaophthalmol.2019.4644
JAMA Ophthalmology Clinical Challenge

Corneal Deposits in a Patient With Anti–Interferon-γ Autoantibody Syndrome

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):310-311. doi:10.1001/jamaophthalmol.2019.4925

A woman in her 30s was referred for corneal opacities. Her medical history was notable for keratoconjunctivitis sicca, Hashimoto thyroiditis, and anti–interferon-γ autoantibody syndrome. She had previously been diagnosed with Mycobacterium avium complex infection. On examination, she had no visual concerns. Her visual acuity was 20/20 OU. What is your diagnosis?

Ocular Juvenile Xanthogranuloma in an Older Teenager

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2020;138(3):312-313. doi:10.1001/jamaophthalmol.2019.4982

A 19-year-old man presented with redness and photophobia that had recurred in the left eye for the past year. The patient had been treated previously with topical corticosteroid therapy and reported temporary relief. A full review of systems was negative for other abnormalities. What would you do next?

Anterior Optic Neuropathy in a Patient With Cyclical Fevers

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2020;138(3):314-315. doi:10.1001/jamaophthalmol.2019.4987

A 41-year-old man presented for evaluation of 2 weeks of blurred vision and pain in the left eye. What would you do next?

Retinal Pigment Abnormalities in a Woman With Diabetes

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2020;138(3):316-317. doi:10.1001/jamaophthalmol.2019.4992

A 49-year-old woman presented with abnormal retinal pigmentation. The patient’s medical history was significant for type 2 diabetes and thyroid cancer that was in remission. The patient’s brother had been previously diagnosed with pattern dystrophy and hearing loss. What would you do next?

Observation

Relapsing Pigment Epithelial Detachment in Central Serous Chorioretinopathy After Dilated Eye Examination

Abstract Full Text
JAMA Ophthalmol. 2020;138(3):318-319. doi:10.1001/jamaophthalmol.2019.5946

This case report describes a central serous chorioretinopathy–related pigment epithelial defect associated with application of phenylephrine, 2.5%.

Ophthalmic Images

Atypical Presentation of Conjunctival Vascular Malformation

Abstract Full Text
online only
JAMA Ophthalmol. 2020;138(3):e190895. doi:10.1001/jamaophthalmol.2019.0895

A 79-year-old man with a history of blunt trauma noted a new, colored lesion with notable features in his eye.

Asymmetry in Pigmented Paravenous Retinochoroidal Atrophy

Abstract Full Text
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JAMA Ophthalmol. 2020;138(3):e190911. doi:10.1001/jamaophthalmol.2019.0911

A 15-year-old boy presents with asymmetric perivenous bone spicule pigment consistent with pigmented paravenous retinochoroidal atrophy.

Ciprofloxacin Corneal Deposits With Complete Dissipation After Switching to Moxifloxacin

Abstract Full Text
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JAMA Ophthalmol. 2020;138(3):e190921. doi:10.1001/jamaophthalmol.2019.0921

An elderly patient presented with white corneal deposits on an eye that had been treated with ciprofloxacin, 0.3%, for Pseudomonas aeruginosa; these were associated with changes in pH level pursuant to the infection.

Fundus Abnormalities in Acute Leukemia

Abstract Full Text
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JAMA Ophthalmol. 2020;138(3):e190934. doi:10.1001/jamaophthalmol.2019.0934

A 13-year-old with a medullar and meningeal relapse of T-cell acute lymphocytic leukemia presents with decreased visual acuity in both eyes from a rare, leukemia-associated cause.

Correction

Errors in Author Byline

Abstract Full Text
free access
JAMA Ophthalmol. 2020;138(3):319. doi:10.1001/jamaophthalmol.2019.6002
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2020;138(3):235. doi:10.1001/jamaophthalmol.2019.3842
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