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April 2019 - January 1929

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October 2013, Vol 131, No. 10, Pages 1-1372

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
free access
JAMA Ophthalmol. 2013;131(10):1259. doi:10.1001/jamaophthalmol.2013.4136
Viewpoint

Genetic Testing for Inherited Eye Disease: Who Benefits?

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1265-1266. doi:10.1001/jamaophthalmol.2013.4509

A New Target for Glaucoma Therapy

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):E1. doi:10.1001/jamaophthalmol.2013.6867
Original Investigation

Clinical Sciences

Analysis of Morphological Features and Vascular Layers of Choroid in Diabetic Retinopathy Using Spectral-Domain Optical Coherence Tomography

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1267-1274. doi:10.1001/jamaophthalmol.2013.4321

Adhi et al analyze the morphological features and vascular layers of the choroid in patients with diabetic retinopathy using spectral-domain optical coherence tomography.

Clinical Sciences

Paracentral Acute Middle Maculopathy: A New Variant of Acute Macular Neuroretinopathy Associated With Retinal Capillary Ischemia

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1275-1287. doi:10.1001/jamaophthalmol.2013.4056

Sarraf and coauthors characterize a new spectral domain optical coherence tomography presentation of acute macular neuroretinopathy as a paracentral acute middle maculopathy.

Clinical Sciences

Phase 1 Clinical Trials of a Selective Rho Kinase Inhibitor, K-115

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1288-1295. doi:10.1001/jamaophthalmol.2013.323

In a randomized double-masked phase 1 clinical trial, Tanihara et al studied the interocular pressure–lowering effects and safety of topical administration of a selective Rho kinase inhibitor, K-115, in healthy male adult volunteers. In the initial single-instillation trial and the repeated-instillation trial, 50 healthy volunteers were treated with placebo or K-115.

Ophthalmic Molecular Genetics

Further Genetic and Clinical Insights of Posterior Polymorphous Corneal Dystrophy 3

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1296-1303. doi:10.1001/jamaophthalmol.2013.405

Liskova et al report 2 novel ZEB1 mutations identified in 2 Czech probands with posterior polymorphous corneal dystrophy 3 and provide a detailed phenotypic description.

Clinical Sciences

Relationship Between Dry Eye Symptoms and Pain Sensitivity

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1304-1308. doi:10.1001/jamaophthalmol.2013.4399

Vehof et al demonstrate an association between reduced pain tolerance, as measured by a heat pain stimulus, and the presence of dry eye symptoms in a large sample of population-representative women.

Clinical Sciences

Visual Outcomes After Early Vitreous Surgery for Aggressive Posterior Retinopathy of Prematurity

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1309-1313. doi:10.1001/jamaophthalmol.2013.4148

Azuma et al evaluate visual outcomes in eyes with aggressive posterior retinopathy of prematurity after early vitreous surgery.

Clinical Sciences

Early-Onset Foveal Involvement in Retinitis Punctata Albescens With Mutations in RLBP1

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1314-1323. doi:10.1001/jamaophthalmol.2013.4476

Dessalces et al examine a large series of patients with retinitis punctata albescens (RPA) to document disease progression and visual function.

Clinical Sciences

Expanded Clinical Spectrum of Enhanced S-Cone Syndrome

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1324-1330. doi:10.1001/jamaophthalmol.2013.4349

Yzer et al expand the clinical spectrum of enhanced S-cone syndrome due to mutations in the NR2E3 gene.

Clinical Sciences

Development and Validation of the Dry Eye–Related Quality-of-Life Score Questionnaire

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1331-1338. doi:10.1001/jamaophthalmol.2013.4503

Sakane et al develop and validate a questionnaire to evaluate the multifaceted effect of dry eye disease on patients’ daily life, including mental health.

Journal Club

Patient-Reported Visual Function Outcomes Improve After Ranibizumab Treatment in Patients With Vision Impairment Due to Diabetic Macular Edema: Randomized Clinical Trial

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1339-1347. doi:10.1001/jamaophthalmol.2013.4592

Mitchell and colleagues examine the effect of intravitreal ranibizumab treatment compared with laser on patient-reported visual function.

Clinical Sciences

Evolution of Vitreomacular Detachment in Healthy Subjects

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1348-1352. doi:10.1001/jamaophthalmol.2013.4578

Itakura and Kishi describe the role of the posterior precortical vitreous pocket in early-stage posterior vitreous detachments in healthy individuals.

Special Communication

An Eye Chart for Edgar Degas

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1353-1355. doi:10.1001/jamaophthalmol.2013.1967
Surgical Technique

New Ab Interno Technique for Removal of Iris-Embedded EX-PRESS Shunt and Chronic Eye Pain Caused by Shunt Malpositioning

Abstract Full Text
free access has multimedia
JAMA Ophthalmol. 2013;131(10):1356-1358. doi:10.1001/jamaophthalmol.2013.4274

Grover et al describe a clear corneal ab interno technique to remove a nonfunctioning and/or malpositioned EX-PRESS shunt. They also describe a new finding, chronic eye pain from internal malpositioning of the shunt, which was completely relieved by shunt removal.

Illuminated Ando Plombe for Optimal Positioning in Highly Myopic Eyes With Vitreoretinal Diseases Secondary to Posterior Staphyloma

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1359-1362. doi:10.1001/jamaophthalmol.2013.4558
Research Letter

Acute Posterior Multifocal Placoid Pigment Epitheliopathy as a Choroidopathy: What We Learned From Adaptive Optics Imaging

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1363-1364. doi:10.1001/jamaophthalmol.2013.4196

Vismodegib as Eye-Sparing Adjuvant Treatment for Orbital Basal Cell Carcinoma

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1364-1366. doi:10.1001/jamaophthalmol.2013.4430

Bridging the Language Barrier in Health Awareness

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1367. doi:10.1001/jamaophthalmol.2013.4285

Irreversible Blindness Following Intravenous Streptokinase

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1368-1369. doi:10.1001/jamaophthalmol.2013.4489
Comment & Response

When You Can Have the Bird Without Shooting It!Extramacular Enhanced Depth Optical Coherence Tomography in Birdshot Chorioretinopathy

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1369. doi:10.1001/jamaophthalmol.2013.4706

When You Can Have the Bird Without Shooting It!: Extramacular Enhanced Depth Optical Coherence Tomography in Birdshot Chorioretinopathy—Reply

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1369-1370. doi:10.1001/jamaophthalmol.2013.5367

Complications of Pneumatic Retinopexy

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1370. doi:10.1001/jamaophthalmol.2013.4590

Complications of Pneumatic Retinopexy—Reply

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1370-1371. doi:10.1001/jamaophthalmol.2013.5371

Detection of Antiretinal Autoantibodies in Serum by Western Blotting

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1371. doi:10.1001/jamaophthalmol.2013.4588

Detection of Antiretinal Autoantibodies in Serum by Western Blotting–Reply

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1372. doi:10.1001/jamaophthalmol.2013.5369
Ophthalmic Images

Mycobacterium abscessus Scleritis Following Intravitreous Injection of Bevacizumab

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):No Pagination Specified. doi:10.1001/jamaophthalmol.2013.2138

Choroidal Detachment Due to Hypotony After Intravitreal Injection of Dexamethasone Implant

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1. doi:10.1001/jamaophthalmol.2013.2526

Entopic Image of Dislocated Intraocular Lens

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1. doi:10.1001/jamaophthalmol.2013.4522

Uveal Coloboma

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1274. doi:10.1001/jamaophthalmol.2013.4515

Surgeon's Corner

Intraocular and Orbital Hemorrhage in a Patient With Dengue Fever During Cataract Surgery

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1313. doi:10.1001/jamaophthalmol.2013.4566

Initial Presentation of Pseudoxanthoma Elasticum

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1352. doi:10.1001/jamaophthalmol.2013.4511

Recurrent Herpes Simplex Keratitis Adjacent to Femtosecond Laser Arcuate Keratotomies

Abstract Full Text
JAMA Ophthalmol. 2013;131(10):1372. doi:10.1001/jamaophthalmol.2013.4528
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2013;131(10):1263. doi:10.1001/jamaophthalmol.2013.4134
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