In a phase 3, double-masked, randomized, multicenter clinical trial, the Diabetic Retinopathy Clinical Research Network evaluates intravitreal ranibizumab compared with intravitreal saline injections on vitrectomy rates for vitreous hemorrhage from proliferative diabetic retinopathy.
Gower et al determine whether a new surgical clamp, the trachomatous trichiasis (TT) clamp, reduces unfavorable postoperative outcomes compared with standard bilamellar tarsal rotation (BLTR) instrumentation.
Bronstad and coauthors examine how central field loss affects reaction time to pedestrians.
Ray et al analyze the relationship between fluoroquinolone use at presentation and minimum inhibitory concentration in bacterial keratitis.
You et al investigate structural and spatial relationships between focal lamina cribrosa defects and glaucomatous optic disc changes such as neuroretinal rim thinning/notching and acquired pits of the optic nerve.
Tony Realini, MD, MPH, evaluated the efficacy of selective laser trabeculoplasty (SLT) for the treatment of open-angle glaucoma (OAG) in an African-derived population in the developing world.`
In a retrospective case series, Shields et al compare the clinical features of primary vs secondary retinal vasoproliferative tumors.
Liu and colleagues tested the hypothesis that the natural history of choroidal neovascularization lesion size is uniform across all prior randomized controlled clinical trials of exudative age-related macular degeneration (AMD), with apparent differences arising from different entry times of eyes into clinical trials.
Keane and coauthors combine “extramacular” and “enhanced depth” optical coherence tomographic (OCT) scanning protocols to facilitate enhanced characterization of patients with birdshot chorioretinopathy. Spectral-domain OCT images were prospectively collected from 24 eyes of 12 patients with birdshot chorioretinopathy.
Abràmoff and coauthors examine the sensitivity and specificity of the Iowa Detection Program to detect referable diabetic retinopathy.
Desai and coworkers conducted a retrospective medical record review of 122 patients in a cluster outbreak of methanol poisoning to determine whether laboratory markers of methanol ingestion and subsequent toxicity can serve as predictors of visual outcomes in patients.
Gerstenblith and colleagues evaluate the effects of high-dose oral omega-3 fatty acid supplementation on electroretinography and omega-3 index in patients with dry age-related macular degeneration.
In a retrospective medical record review, Herlihy et al examine the clinical and eye movement findings that distinguish abducens palsy from divergence insufficiency and account for these findings based on current knowledge of vergence neurophysiology and saccadic adaptation.
Lavine et al studied whether β-adrenergic blockade inhibits choroidal neovascularization (CNV) in a mouse model of laser-induced CNV and investigated the mechanism by which β-adrenoreceptor antagonism blunts CNV.
Klein et al evaluated population-based data from the Beaver Dam Eye Study to provide estimates of the long-term risk of the incidence and progression of agerelated macular degeneration and its lesions by age and genetic risk alleles for CFH and ARMS2.
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