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July 2019 - January 1929

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Issue

November 2014, Vol 132, No. 11, Pages 1265-1383

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1265. doi:10.1001/jamaophthalmol.2013.5968
Viewpoint

Endophthalmitis Prophylaxis for Cataract Surgery: Are Intracameral Antibiotics Necessary?

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1269-1270. doi:10.1001/jamaophthalmol.2014.2052
Original Investigation

Journal Club

Proteomic Landscape of the Human Choroid–Retinal Pigment Epithelial Complex

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JAMA Ophthalmol. 2014;132(11):1271-1281. doi:10.1001/jamaophthalmol.2014.2065

Skeie and Mahajan characterize the proteome of the human choroid–retinal pigment epithelial (RPE) complex and identify differentially expressed proteins in specific anatomic regions.

A Cost-Minimization Analysis Comparing Immediate Sequential Cataract Surgery and Delayed Sequential Cataract Surgery From the Payer, Patient, and Societal Perspectives in the United States

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1282-1288. doi:10.1001/jamaophthalmol.2014.2074

Neel performed a cost-minimization analysis comparing immediate vs delayed sequential cataract surgery from the payer, patient, and societal perspectives for the West Tennessee region and nationally. Outcome measures were cataract surgery volume and eligibility estimates, 2012 Medicare reimbursement schedules, and actual or estimated patient cost data.

Restoration of Corneal Sensation With Regional Nerve Transfers and Nerve Grafts: A New Approach to a Difficult Problem

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1289-1295. doi:10.1001/jamaophthalmol.2014.2316

Elbaz and colleagues assessed the outcomes of a novel sensory reconstructive technique for the treatment of corneal anesthesia.

Effect of Cataract Extraction on the Visual Field Decay Rate in Patients With Glaucoma

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1296-1302. doi:10.1001/jamaophthalmol.2014.2326

Lee et al evaluate the effect of cataract surgery on the slow and fast components of visual field decay. Among 85 eyes of 68 patients with open-angle glaucoma, the slow and fast components were measured before and after cataract surgery. Linear regressions of the mean deviation and the visual field parameter were compared before and after surgery.

Retinal Metastasis From Systemic Cancer in 8 Cases

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1303-1308. doi:10.1001/jamaophthalmol.2014.2406

Eight patients with retinal metastasis from cutaneous melanoma (n=4) or remote carcinoma (n=4) showed inner retinal tumor (n=7), vitreous seeds (n=3), and vitreous hemorrhage (n=3). Of 7 who were followed up, 5 died of systemic cancer within 1 month.

Disorganization of the Retinal Inner Layers as a Predictor of Visual Acuity in Eyes With Center-Involved Diabetic Macular Edema

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1309-1316. doi:10.1001/jamaophthalmol.2014.2350

At a tertiary care facility, Sun et al determine whether baseline or early change in the novel SD-OCT parameter disorganization of the retinal inner layers is predictive of VA in eyes with center-involved diabetic macular edema. Among 96 adult participants (120 eyes), the main outcomes and measures were VA and SD-OCT–derived retinal morphology.

Cardiovascular Events and Bleeding Risk Associated With Intravitreal Antivascular Endothelial Growth Factor Monoclonal Antibodies: Systematic Review and Meta-analysis

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1317-1326. doi:10.1001/jamaophthalmol.2014.2333

Thulliez et al conduct a systematic review and meta-analysis to evaluate the risk of major cardiovascular and nonocular hemorrhagic events in patients with age-related macular degeneration, diabetes mellitus–associated macular edema, or retinal vein occlusion who receive intravitreal antivascular endothelial growth factor monoclonal antibodies (anti-VEGF) (ranibizumab and bevacizumab).

Clinical Trial

Refractive Outcomes Following Bevacizumab Monotherapy Compared With Conventional Laser Treatment: A Randomized Clinical Trial

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1327-1333. doi:10.1001/jamaophthalmol.2014.2772

Geloneck et al report refractive outcomes in children who had developed retinopathy of prematurity (ROP) in zone I or zone II posterior as stage 3+ ROP or aggressive posterior ROP and had received intravitreal bevacizumab or laser as preterm infants in a clinical trial.

Prevalence of and Risk Factors for Diabetic Macular Edema in the United States

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1334-1340. doi:10.1001/jamaophthalmol.2014.2854

Varma et al estimate the prevalence of diabetic macular edema in the US population and identify associated risk factors.

Clinical and Molecular Characterization of Enhanced S-Cone Syndrome in Children

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1341-1349. doi:10.1001/jamaophthalmol.2014.2343

Among 9 children with enhanced S-cone syndrome from 5 families, Hull et al report the clinical phenotype and molecular genetic findings. Patients underwent full ophthalmic examination, electrophysiological testing, and retinal imaging. Bidirectional Sanger sequencing of all exons and intron-exon boundaries of NR2E3 was performed.

Human Ciliary Epithelium as a Source of Synthesis and Secretion of Vascular Endothelial Growth Factor in Neovascular Glaucoma

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1350-1354. doi:10.1001/jamaophthalmol.2014.2356

Chalam and coauthors investigate the ciliary epithelium as a possible source of vascular endothelial growth factor in human eyes enucleated for intractable neovascular glaucoma.

Brief Report

In Vivo Effects of Femtosecond Laser–Assisted Keratoplasty

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1355-1358. doi:10.1001/jamaophthalmol.2014.2389

Banitt et al evaluate the smoothness of the deeper lamellar surface as cut by the femtosecond laser in 2 patients undergoing penetrating keratoplasty.

A Cost and Policy Analysis Comparing Immediate Sequential Cataract Surgery and Delayed Sequential Cataract Surgery From the Physician Perspective in the United States

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1359-1362. doi:10.1001/jamaophthalmol.2014.3335

This cost and policy analysis evaluates the financial and efficiency effects on US physicians of a transition from delayed sequential cataract surgery to immediate sequential cataract surgery.

Invited Commentary

Benefits of and Barriers to Immediate Sequential Cataract Surgery

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1362-1363. doi:10.1001/jamaophthalmol.2014.3637
Surgical Technique

Small-Bubble Deep Anterior Lamellar Keratoplasty Technique

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1369-1371. doi:10.1001/jamaophthalmol.2014.2756
JAMA Ophthalmology Clinical Challenge

Acute Postoperative Visual Loss

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1365-1366. doi:10.1001/jamaophthalmol.2014.3352

Sudden-Onset Paracentral Vision Loss

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1367-1368. doi:10.1001/jamaophthalmol.2014.3347
Research Letter

Stability of Melphalan Solution for Intravitreal Injection for Retinoblastoma

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1372-1373. doi:10.1001/jamaophthalmol.2014.2324

Atypical Lymphocytic Angiitis of the Optic Nerve and Central Nervous System

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1373-1375. doi:10.1001/jamaophthalmol.2014.2786
Observation

Optic Disc Pit Maculopathy Recurring in the Absence of Vitreous Gel

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1375-1376. doi:10.1001/jamaophthalmol.2014.2054

Traumatic Prepapillary Loop Torsion and Associated Branch Retinal Artery Occlusion

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1376-1377. doi:10.1001/jamaophthalmol.2014.2415

Thalidomide for Recalcitrant Nodular Scleritis in Sarcoidosis

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1377-1379. doi:10.1001/jamaophthalmol.2014.2420

Conjunctival Intralymphatic Small Cell Lymphocytostasis Associated With a Salmon Patch

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1379-1381. doi:10.1001/jamaophthalmol.2014.2821

Candida glabrata Endophthalmitis Transmitted From Graft to Host After Descemet Stripping Automated Endothelial Keratoplasty

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1381-1383. doi:10.1001/jamaophthalmol.2014.2780
Ophthalmic Images

Using Canalography to Visualize the In Vivo Aqueous Humor Outflow Conventional Pathway in Humans

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1281. doi:10.1001/jamaophthalmol.2014.567

Intrathecal Anesthesia After Retrobulbar Block, With Terson-Like Syndrome

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1295. doi:10.1001/jamaophthalmol.2014.168

Starry Sky

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1340. doi:10.1001/jamaophthalmol.2014.563

Xanthic Scotoma

Abstract Full Text
JAMA Ophthalmol. 2014;132(11):1354. doi:10.1001/jamaophthalmol.2014.573
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2014;132(11):1267. doi:10.1001/jamaophthalmol.2013.5969
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