Skeie and Mahajan characterize the proteome of the human choroid–retinal pigment epithelial (RPE) complex and identify differentially expressed proteins in specific anatomic regions.
Neel performed a cost-minimization analysis comparing immediate vs delayed sequential cataract surgery from the payer, patient, and societal perspectives for the West Tennessee region and nationally. Outcome measures were cataract surgery volume and eligibility estimates, 2012 Medicare reimbursement schedules, and actual or estimated patient cost data.
Elbaz and colleagues assessed the outcomes of a novel sensory reconstructive technique for the treatment of corneal anesthesia.
Lee et al evaluate the effect of cataract surgery on the slow and fast components of visual field decay. Among 85 eyes of 68 patients with open-angle glaucoma, the slow and fast components were measured before and after cataract surgery. Linear regressions of the mean deviation and the visual field parameter were compared before and after surgery.
Eight patients with retinal metastasis from cutaneous melanoma (n=4) or remote carcinoma (n=4) showed inner retinal tumor (n=7), vitreous seeds (n=3), and vitreous hemorrhage (n=3). Of 7 who were followed up, 5 died of systemic cancer within 1 month.
At a tertiary care facility, Sun et al determine whether baseline or early change in the novel SD-OCT parameter disorganization of the retinal inner layers is predictive of VA in eyes with center-involved diabetic macular edema. Among 96 adult participants (120 eyes), the main outcomes and measures were VA and SD-OCT–derived retinal morphology.
Thulliez et al conduct a systematic review and meta-analysis to evaluate the risk of major cardiovascular and nonocular hemorrhagic events in patients with age-related macular degeneration, diabetes mellitus–associated macular edema, or retinal vein occlusion who receive intravitreal antivascular endothelial growth factor monoclonal antibodies (anti-VEGF) (ranibizumab and bevacizumab).
Geloneck et al report refractive outcomes in children who had developed retinopathy of prematurity (ROP) in zone I or zone II posterior as stage 3+ ROP or aggressive posterior ROP and had received intravitreal bevacizumab or laser as preterm infants in a clinical trial.
Varma et al estimate the prevalence of diabetic macular edema in the US population and identify associated risk factors.
Among 9 children with enhanced S-cone syndrome from 5 families, Hull et al report the clinical phenotype and molecular genetic findings. Patients underwent full ophthalmic examination, electrophysiological testing, and retinal imaging. Bidirectional Sanger sequencing of all exons and intron-exon boundaries of NR2E3 was performed.
Chalam and coauthors investigate the ciliary epithelium as a possible source of vascular endothelial growth factor in human eyes enucleated for intractable neovascular glaucoma.
Banitt et al evaluate the smoothness of the deeper lamellar surface as cut by the femtosecond laser in 2 patients undergoing penetrating keratoplasty.
This cost and policy analysis evaluates the financial and efficiency effects on US physicians of a transition from delayed sequential cataract surgery to immediate sequential cataract surgery.
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