Sabel and Gudlin determine if behavioral activation of areas of residual visual using daily 1-hour vision restoration training for glaucoma for 3 months improves detection accuracy compared with placebo. Interventions were computer-based vision restoration training for glaucoma or visual discrimination placebo training in the intact visual field.
Jampel et al assess the effectiveness of intraocular pressure (IOP)–lowering medications in patients with open-angle glaucoma.
Asrani et al determine the frequency and distribution of SD-OCT imaging artifacts in patients being evaluated for glaucoma. A retrospective cross-sectional study design was used to examine SD-OCT images of 277 consecutive patients. Retinal nerve fiber layer and macular thickness scans were included. Examples of common artifacts are provided.
Greninger et al evaluate the effectiveness and complications of selective laser trabeculoplasty (SLT) performed by resident ophthalmologists and identify predictors for success.
Koilkonda et al demonstrate the safety and effects of the gene therapy vector to be used in a proposed gene therapy clinical trial for Leber hereditary optic neuropathy (LHON).
Moss et al investigated the associations of age, sex, and race/ethnicity with visual outcomes following acute optic neuritis through application of longitudinal data analysis techniques to the Optic Neuritis Treatment Trial data set. Patients of black and white race/ethnicity who enrolled in the trial within 8 days of symptom onset were included.
Lam et al monitor the natural history of G11778A Leber hereditary optic neuropathy to determine the optimal end points to assess the safety and efficacy of a planned gene therapy trial.
Greenberg et al categorize achromatopsia into clinically identifiable stages using spectral-domain optical coherence tomography and describe fundus autofluorescence imaging in this condition.
Klein and colleagues examined the relationships of markers of inflammation, oxidative stress, and endothelial dysfunction to the 20-year cumulative incidence of early age-related macular degeneration.
Sloan and Hanrahan assess the effects of new therapies for treating exudative ARMD among newly diagnosed Medicare beneficiaries. The study used a combination of a regression discontinuity design and propensity score matching. Outcome measures were onset of decrease in vision, vision loss or blindness, depression, and admission to a long-term care facility.
Semba et al investigate the relationship between serum carboxymethyllysine, a major circulating advanced glycation end product, and age-related macular degeneration (AMD) in older adults.
Gibson examines whether availability of ophthalmologists and optometrists is associated with access to eye care for individuals with diabetes, diabetic retinopathy, or age-related macular degeneration.
Wong and coauthors examine updated US retinoblastoma incidence patterns by sex, age at diagnosis, laterality, race/ethnicity, and year of diagnosis.
Fahim et al evaluated a woman with acute panretinal dysfunction after intravitreous ocriplasmin injection for a small macular hole with vitreomacular adhesion. B-waves were reduced more than A-waves were, suggesting postreceptoral dysfunction and decreased photoreceptor activity.
Tibbetts and coauthors describe a woman with symptomatic vitreomacular traction who received intravitreal ocriplasmin and experienced darkening of vision.
Simunovic discusses the El Greco fallacy, which posits that the elongation evident in El Greco’s art reflects an underlying perceptual elongation of objects caused by astigmatism.
van Dijk et al describe a new surgical technique using a midstromal implant of a donor-isolated Bowman layer graft to reduce ectasia in eyes with advanced keratoconus.
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