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December 2020 - January 1929

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September 2014, Vol 132, No. 9, Pages 1041-1153

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2014;132(9):1041. doi:10.1001/jamaophthalmol.2013.5958
Viewpoint

Translational Science With Clinical Promise

The First International Optogenetic Therapies for Vision Symposium: Translational Medicine in Progress

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JAMA Ophthalmol. 2014;132(9):1043-1044. doi:10.1001/jamaophthalmol.2014.1420
Original Investigation

Effect of a Teleretinal Screening Program on Eye Care Use and Resources

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JAMA Ophthalmol. 2014;132(9):1045-1051. doi:10.1001/jamaophthalmol.2014.1051

Chasan and coauthors evaluate the effect of a community-based diabetic teleretinal screening program on eye care use and resources.

Telemedicine Diagnosis of Cytomegalovirus Retinitis by Nonophthalmologists

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JAMA Ophthalmol. 2014;132(9):1052-1058. doi:10.1001/jamaophthalmol.2014.1108

Yen et al determine the accuracy of photographic graders who were not ophthalmologists in diagnosing cytomegalovirus retinitis from digital fundus photographs.

Postoperative Glaucoma Following Infantile Cataract Surgery: An Individual Patient Data Meta-analysis

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JAMA Ophthalmol. 2014;132(9):1059-1067. doi:10.1001/jamaophthalmol.2014.1042

Mataftsi et al assess the effect of primary intraocular lens implantation and surgery timing on the incidence of postoperative glaucoma in infants.

Optic Disc Characteristics in Patients With Glaucoma and Combined Superior and Inferior Retinal Nerve Fiber Layer Defects

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JAMA Ophthalmol. 2014;132(9):1068-1075. doi:10.1001/jamaophthalmol.2014.1056

Choi et al identify the optic disc characteristics related to bihemispheric retinal nerve fiber layer (RNFL) defects in early-stage glaucoma.

Identification of CNGA3 Mutations in 46 Families: Common Cause of Achromatopsia and Cone-Rod Dystrophies in Chinese Patients

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JAMA Ophthalmol. 2014;132(9):1076-1083. doi:10.1001/jamaophthalmol.2014.1032

To identify CNGA3 mutations, Li et al examine clinical data and genomic DNA in 267 Chinese probands from 138 families with cone dystrophies and 129 families with Leber congenital amaurosis. They study variants in CNGA3 and associated phenotypes, assessed by Sanger sequencing of CNGA3, bioinformatics of variants, and segregation analysis.

Concentric Macular Rings Sign in Patients With Foveal Hypoplasia

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JAMA Ophthalmol. 2014;132(9):1084-1088. doi:10.1001/jamaophthalmol.2014.1715

Cornish and coauthors describe the concentric macular rings found on infrared reflectance in patients with foveal hypoplasia.

Acute Zonal Occult Outer Retinopathy: A Classification Based on Multimodal Imaging

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JAMA Ophthalmol. 2014;132(9):1089-1098. doi:10.1001/jamaophthalmol.2014.1683

Mrejen et al propose a classification of acute zonal occult outer retinopathy (AZOOR) based on clinical fundus and multimodal imaging. They performed a retrospective review of patients diagnosed as having AZOOR or AZOOR complex and assembled 30 cases. Multimodal imaging had been performed in most patients at the initial visit or at subsequent follow-up visits.

Fluorescence Adaptive Optics Scanning Laser Ophthalmoscope for Detection of Reduced Cones and Hypoautofluorescent Spots in Fundus Albipunctatus

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JAMA Ophthalmol. 2014;132(9):1099-1104. doi:10.1001/jamaophthalmol.2014.1079

Song et al study the cone photoreceptors and the albipunctate spots in a patient with fundus albipunctatus at single cell resolution using a fluorescence adaptive optics scanning laser ophthalmoscope

Effect of Disease Stage on Progression of Hydroxychloroquine Retinopathy

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JAMA Ophthalmol. 2014;132(9):1105-1112. doi:10.1001/jamaophthalmol.2014.1099

Marmor and Hu determine the relationship between progression of retinopathy and the severity of disease, using objective data from optical coherence tomography, and assess the value of early screening for the toxic effects of hydroxychloroquine.

Reproducibility of Spectral-Domain Optical Coherence Tomography Retinal Thickness Measurements and Conversion to Equivalent Time-Domain Metrics in Diabetic Macular Edema

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JAMA Ophthalmol. 2014;132(9):1113-1122. doi:10.1001/jamaophthalmol.2014.1698

Bressler et al evaluate the reproducibility of retinal thickness measurements from optical coherence tomography (OCT) images obtained by time-domain instruments and formulate equations to convert retinal thickness measurements from spectral-domain OCT to equivalent values on time-domain OCT.

Prolonged Curvularia Endophthalmitis Due to Organism Sequestration

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JAMA Ophthalmol. 2014;132(9):1123-1126. doi:10.1001/jamaophthalmol.2014.1069

Rachitskaya et al examine the clinical course of 6 postoperative and trauma-related cases of endophthalmitis caused by Curvularia.

Management of Functional Epiphora in Patients With an Anatomically Patent Dacryocystorhinostomy

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JAMA Ophthalmol. 2014;132(9):1127-1132. doi:10.1001/jamaophthalmol.2014.1093

Shams et al investigate the management and success rate of so-called “functional failure” of dacryocystorhinostomy for nasolacrimal duct obstruction by experienced lacrimal surgeons.

Brief Report

Histopathological and Immunohistochemical Analysis of Melt-Associated Retroprosthetic Membranes in the Boston Type 1 Keratoprosthesis

Abstract Full Text
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JAMA Ophthalmol. 2014;132(9):1133-1136. doi:10.1001/jamaophthalmol.2014.1959

Hou et al identify the histological and immunohistochemical characteristics of retroprosthetic membranes associated with corneal melt among patients who underwent Boston type 1 keratoprosthesis explantation because of donor corneal melt. Seven specimens from 7 eyes were stained for analysis, and light microscopy and XY-karyotyping were performed.

Effect of Doxycycline vs Placebo on Retinal Function and Diabetic Retinopathy Progression in Mild to Moderate Nonproliferative Diabetic Retinopathy: A Randomized Proof-of-Concept Clinical Trial

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JAMA Ophthalmol. 2014;132(9):1137-1142. doi:10.1001/jamaophthalmol.2014.1422

Scott et al investigate whether low-dose oral doxycycline can improve or slow the deterioration of retinal function and can induce regression or slow disease progression in nonprolific diabetic retinopathy (NPDR).

JAMA Ophthalmology Clinical Challenge

Intractable Choroidal Effusion With Exudative Retinal Detachment in Sturge-Weber Syndrome

Abstract Full Text
JAMA Ophthalmol. 2014;132(9):1143-1144. doi:10.1001/jamaophthalmol.2014.2464

Diffusely Swollen Eyelid

Abstract Full Text
JAMA Ophthalmol. 2014;132(9):1145-1146. doi:10.1001/jamaophthalmol.2014.1964
Research Letter

Enhanced Vitreous Imaging Technique With Spectral-Domain Optical Coherence Tomography for Evaluation of Posterior Vitreous Detachment

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JAMA Ophthalmol. 2014;132(9):1148-1150. doi:10.1001/jamaophthalmol.2014.1037
Observation

Development of Bilateral Acquired Toxoplasmic Retinochoroiditis During Erlotinib Therapy

Abstract Full Text
JAMA Ophthalmol. 2014;132(9):1150-1152. doi:10.1001/jamaophthalmol.2014.1088
Ophthalmic Images

Nevus in a Pterygium

Abstract Full Text
JAMA Ophthalmol. 2014;132(9):1044. doi:10.1001/jamaophthalmol.2013.4406

Acquired Trichomegaly: Trichomegaly Secondary to Erlotinib

Abstract Full Text
JAMA Ophthalmol. 2014;132(9):1051. doi:10.1001/jamaophthalmol.2014.545

Vitelliform Macular Dystrophy

Abstract Full Text
JAMA Ophthalmol. 2014;132(9):1098. doi:10.1001/jamaophthalmol.2013.4265

Congenital Lamellar Cataract

Abstract Full Text
JAMA Ophthalmol. 2014;132(9):1122. doi:10.1001/jamaophthalmol.2013.5851

Optic Nerve Pit–Associated Choroidal Cleft

Abstract Full Text
JAMA Ophthalmol. 2014;132(9):1142. doi:10.1001/jamaophthalmol.2014.174
Comment & Response

Outer Segment Length in Different Best Disease Genotypes

Abstract Full Text
JAMA Ophthalmol. 2014;132(9):1152-1153. doi:10.1001/jamaophthalmol.2014.2980

Outer Segment Length in Different Best Disease Genotypes—Reply

Abstract Full Text
JAMA Ophthalmol. 2014;132(9):1153. doi:10.1001/jamaophthalmol.2014.2984
Correction

Incorrect Spelling of Author’s Last Name

Abstract Full Text
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JAMA Ophthalmol. 2014;132(9):1153. doi:10.1001/jamaophthalmol.2014.3397
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2014;132(9):1042. doi:10.1001/jamaophthalmol.2013.5959
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