This Viewpoint discusses randomizing one eye vs both eyes in ophthalmic clinical trials.
This retrospective observational pilot study suggests that children with a history of amblyopia have impaired visual-auditory speech perception. Early childhood appears to serve as an approximate time point for the development of successful visual-auditory fusion, by which time amblyopia must have either resolved or begun. Interventions to resolve amblyopia may not only influence visual acuity but may also influence the perception of sound.
This randomized clinical trial reports that in a cohort of healthy men, long-term daily supplementation with selenium and/or vitamin E is unlikely to have a large beneficial effect on age-related cataract.
This independent assessment of 8 ophthalmologic conditions in the Cochrane Database of Systematic Reviews found that certain conditions get more focus to create a better representation of what is causing the most disability and mortality within this research database.
This prospective study of syringes containing intravitreal preparations of bevacizumab from compounding pharmacies found that such preparations were negative for microbial contaminants and endotoxin. However, there were variations in protein concentration that appear to be lower than bevacizumab acquired from Genentech.
This cross-sectional study suggests that false-negative response rates have an effect on the ability of automated visual field assessments to rule out glaucoma.
This imaging study found that optical coherence tomography angiography, but not fluorescein angiography, can image all retinal vasculature layers.
This randomized clinical trial found no difference in uncorrected visual acuity or contrast acuity between wavefront-guided and wavefront-optimized refractive surgery.
This retrospective study determines that Medicare beneficiaries with a disorder of binocular vision have significantly higher odds of sustaining a musculoskeletal injury, fracture, or fall.
This case study reports that important retinal vascular changes in MacTel 2 occur in the deep capillary plexus of the retina, a layer poorly visualized by fluorescein angiography and, to a lesser extent, in the inner vascular plexus. The proliferation of vessels in the outer and subretinal spaces may be compensatory for poor retinal perfusion by established vascular layers in the retina.
This retrospective cohort study reports that the Swedish Interactive Thresholding Algorithm is a more precise testing algorithm than the Swedish Interactive Thresholding Algorithm Fast at lower visual field sensitivities, but that this is likely to make a sizeable difference to improving the time to detect visual field progression.
This comparative safety study identifies no association of first-time use of levofloxacin with uveitis.
This case report describes focal macular damage associated with brilliant blue G migration into the subretinal space.
Inoue and coauthors describe Landolt ring–shaped epithelial keratopathy.
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