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May 2019 - January 1929

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Issue

January 2015, Vol 133, No. 1, Pages 5-112

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):5. doi:10.1001/jamaophthalmol.2014.3697
Viewpoint

Randomizing 1 Eye or 2 Eyes: A Missed Opportunity

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):9-10. doi:10.1001/jamaophthalmol.2014.3600

This Viewpoint discusses randomizing one eye vs both eyes in ophthalmic clinical trials.

Original Investigation

Journal Club

The Effect of Amblyopia on Visual-Auditory Speech Perception: Why Mothers May Say “Look At Me When I’m Talking To You”

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):11-16. doi:10.1001/jamaophthalmol.2014.3307

This retrospective observational pilot study suggests that children with a history of amblyopia have impaired visual-auditory speech perception. Early childhood appears to serve as an approximate time point for the development of successful visual-auditory fusion, by which time amblyopia must have either resolved or begun. Interventions to resolve amblyopia may not only influence visual acuity but may also influence the perception of sound.

Age-Related Cataract in Men in the Selenium and Vitamin E Cancer Prevention Trial Eye Endpoints Study: A Randomized Clinical Trial

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):17-24. doi:10.1001/jamaophthalmol.2014.3478

This randomized clinical trial reports that in a cohort of healthy men, long-term daily supplementation with selenium and/or vitamin E is unlikely to have a large beneficial effect on age-related cataract.

Global Burden of Eye and Vision Disease as Reflected in the Cochrane Database of Systematic Reviews

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):25-31. doi:10.1001/jamaophthalmol.2014.3527

This independent assessment of 8 ophthalmologic conditions in the Cochrane Database of Systematic Reviews found that certain conditions get more focus to create a better representation of what is causing the most disability and mortality within this research database.

Evaluation of Compounded Bevacizumab Prepared for Intravitreal Injection

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):32-39. doi:10.1001/jamaophthalmol.2014.3591

This prospective study of syringes containing intravitreal preparations of bevacizumab from compounding pharmacies found that such preparations were negative for microbial contaminants and endotoxin. However, there were variations in protein concentration that appear to be lower than bevacizumab acquired from Genentech.

Role of Visual Field Reliability Indices in Ruling Out Glaucoma

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):40-44. doi:10.1001/jamaophthalmol.2014.3609

This cross-sectional study suggests that false-negative response rates have an effect on the ability of automated visual field assessments to rule out glaucoma.

Retinal Vascular Layers Imaged by Fluorescein Angiography and Optical Coherence Tomography Angiography

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):45-50. doi:10.1001/jamaophthalmol.2014.3616

This imaging study found that optical coherence tomography angiography, but not fluorescein angiography, can image all retinal vasculature layers.

Clinical Trial

Contralateral Eye-to-Eye Comparison of Wavefront-Guided and Wavefront-Optimized Photorefractive Keratectomy: A Randomized Clinical Trial

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):51-59. doi:10.1001/jamaophthalmol.2014.3876

This randomized clinical trial found no difference in uncorrected visual acuity or contrast acuity between wavefront-guided and wavefront-optimized refractive surgery.

Risk of Musculoskeletal Injuries, Fractures, and Falls in Medicare Beneficiaries With Disorders of Binocular Vision

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):60-65. doi:10.1001/jamaophthalmol.2014.3941

This retrospective study determines that Medicare beneficiaries with a disorder of binocular vision have significantly higher odds of sustaining a musculoskeletal injury, fracture, or fall.

Retinal Vascular Layers in Macular Telangiectasia Type 2 Imaged by Optical Coherence Tomographic Angiography

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):66-73. doi:10.1001/jamaophthalmol.2014.3950

This case study reports that important retinal vascular changes in MacTel 2 occur in the deep capillary plexus of the retina, a layer poorly visualized by fluorescein angiography and, to a lesser extent, in the inner vascular plexus. The proliferation of vessels in the outer and subretinal spaces may be compensatory for poor retinal perfusion by established vascular layers in the retina.

Measurement Precision in a Series of Visual Fields Acquired by the Standard and Fast Versions of the Swedish Interactive Thresholding Algorithm: Analysis of Large-Scale Data From Clinics

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):74-80. doi:10.1001/jamaophthalmol.2014.4237

This retrospective cohort study reports that the Swedish Interactive Thresholding Algorithm is a more precise testing algorithm than the Swedish Interactive Thresholding Algorithm Fast at lower visual field sensitivities, but that this is likely to make a sizeable difference to improving the time to detect visual field progression.

Brief Report

Risk for Uveitis With Oral Moxifloxacin: A Comparative Safety Study

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):81-84. doi:10.1001/jamaophthalmol.2014.3598

This comparative safety study identifies no association of first-time use of levofloxacin with uveitis.

Accidental Subretinal Brilliant Blue G Migration During Internal Limiting Membrane Peeling Surgery

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):85-88. doi:10.1001/jamaophthalmol.2014.3869

This case report describes focal macular damage associated with brilliant blue G migration into the subretinal space.

Landolt Ring–Shaped Epithelial Keratopathy: A Novel Clinical Entity of the Cornea

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):89-92. doi:10.1001/jamaophthalmol.2014.2381

Inoue and coauthors describe Landolt ring–shaped epithelial keratopathy.

Surgical Technique

Intravitreal Triamcinolone–Illuminated Cataract Surgery for Patients With Dense Vitreous Hemorrhage

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):93-94. doi:10.1001/jamaophthalmol.2014.3321
JAMA Ophthalmology Clinical Challenge

A Painful Red Eye

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):95-96. doi:10.1001/jamaophthalmol.2014.3888

An Adolescent With a Swollen Nerve

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):97-98. doi:10.1001/jamaophthalmol.2014.4461
Research Letter

Massive Retinal Gliosis in Neurofibromatosis Type 1

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):100-102. doi:10.1001/jamaophthalmol.2014.3958

Subconjunctival Indocyanine Green Identifies Lymphatic Vessels

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):102-104. doi:10.1001/jamaophthalmol.2014.3944
Observation

Intralesional Rituximab for Primary Iris Lymphoma

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):104-105. doi:10.1001/jamaophthalmol.2014.3303

Conjunctival Pseudotumor Caused by Herpes Simplex Virus Infection

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):105-107. doi:10.1001/jamaophthalmol.2014.3316

Bilateral Exudative Retinal Detachment in a Diabetic Patient With Severe Peripheral Retinal Ischemia

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):107-109. doi:10.1001/jamaophthalmol.2014.3491

Rapid Involution of Choroidal Metastasis Secondary to Renal Cell Carcinoma With Oral Sunitinib

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):109-110. doi:10.1001/jamaophthalmol.2014.3931
Comment & Response

Could Progressive Outer Retinal Necrosis Begin With Retinal Deep Capillary Ischemia?

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):110-111. doi:10.1001/jamaophthalmol.2014.3548

Could Progressive Outer Retinal Necrosis Begin With Retinal Deep Capillary Ischemia?—Reply

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):111-112. doi:10.1001/jamaophthalmol.2014.3550
Ophthalmic Images

Conjunctival Rhinosporidiosis

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):39. doi:10.1001/jamaophthalmol.2014.608

Leukemic Retinopathy

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):73. doi:10.1001/jamaophthalmol.2014.577

Concurrent Threshold Retinopathy of Prematurity and Abusive Head Trauma

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):84. doi:10.1001/jamaophthalmol.2014.593

Ultrasonographic Biomicroscopy in Lens-Induced Glaucoma

Abstract Full Text
JAMA Ophthalmol. 2015;133(1):112. doi:10.1001/jamaophthalmol.2014.612

Angioid Streaks in Association With Sickle Thalassemia Trait

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):e141770. doi:10.1001/jamaophthalmol.2014.1770

Optic Nerve Pit and Associated Macular Detachment

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):e141775. doi:10.1001/jamaophthalmol.2014.1775

Trans-Synaptic Degeneration of Lateral Geniculate Nuclei Following Remote Loss of Right Eye

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):e141789. doi:10.1001/jamaophthalmol.2014.1789

Congenital Cataract

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):e141793. doi:10.1001/jamaophthalmol.2014.1793

Posterior Nodular Scleritis

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):e141801. doi:10.1001/jamaophthalmol.2014.1801

Retinopathy of Prematurity Evolution After Laser Treatment: Retcam Findings

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):e141808. doi:10.1001/jamaophthalmol.2014.1808

A 360° Giant Retinal Tear in Stickler Syndrome

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):e141812. doi:10.1001/jamaophthalmol.2014.1812

Prominent Mittendorf Spot

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):e141817. doi:10.1001/jamaophthalmol.2014.1817
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2015;133(1):7. doi:10.1001/jamaophthalmol.2014.3698
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