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April 2020 - January 1929

Decade

Year

Issue

October 2015, Vol 133, No. 10, Pages 1101-1222

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1101. doi:10.1001/jamaophthalmol.2014.3742
Viewpoint

Ebola and the Eye

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1105-1106. doi:10.1001/jamaophthalmol.2015.2400

This Viewpoint discusses how the Ebola virus affects the eye.

Long-term Contributions From the Diabetes Control and Complications Trial Cohort

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1107-1108. doi:10.1001/jamaophthalmol.2015.2735

This Viewpoint explores progress in the process and treatment of diabetes mellitus by long-term follow-up of the Diabetes Control and Complications Trial.

Original Investigation

Distinct Pathways in the Pathogenesis of Sebaceous Carcinomas Implicated by Differentially Expressed MicroRNAs

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1109-1116. doi:10.1001/jamaophthalmol.2015.2310

This study describes differentially expressed microRNAs in a series of periocular sebaceous carcinomas compared with sebaceous adenomas in order to identify pathways driving the pathogenesis of sebaceous carcinoma.

Journal Club

Effects of Azithromycin on Gene Expression Profiles of Proinflammatory and Anti-inflammatory Mediators in the Eyelid Margin and Conjunctiva of Patients With Meibomian Gland Disease

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1117-1123. doi:10.1001/jamaophthalmol.2015.2326

This case-control study evaluates the effects of azithromycin on cytokine expression in patients with meibomian gland disease.

Determination of Feasibility and Utility of Microscope-Integrated Optical Coherence Tomography During Ophthalmic Surgery: The DISCOVER Study RESCAN Results

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1124-1132. doi:10.1001/jamaophthalmol.2015.2376

This report highlights the 1-year results of the RESCAN 700 portion of the DISCOVER study in order to assess the feasibility and effect on surgical decision making of a microscope-integrated intraoperative optical coherence tomography system.

Predicted and Measured Retinal Nerve Fiber Layer Thickness From Time-Domain Optical Coherence Tomography Compared With Spectral-Domain Optical Coherence Tomography

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1135-1143. doi:10.1001/jamaophthalmol.2015.2427

This cross-sectional study compares the agreement of measured and predicted peripapillary retinal nerve fiber layer thickness using different equations based on peripapillary retinal nerve fiber layer thickness measurements obtained by time-domain optical coherence tomography and spectral-domain optical coherence tomography.

Association Between Body Levels of Trace Metals and Glaucoma Prevalence

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1144-1150. doi:10.1001/jamaophthalmol.2015.2438

This cross-sectional population-based study based on the Korea National Health and Nutrition Examination Survey investigates associations between body levels of trace metals and the prevalence of glaucoma.

Structural Characteristics of the Acquired Optic Disc Pit and the Rate of Progressive Retinal Nerve Fiber Layer Thinning in Primary Open-Angle Glaucoma

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1151-1158. doi:10.1001/jamaophthalmol.2015.2453

This case-control study investigates the role of optic disc pits in the global and focal progression of glaucoma in a population with primary open-angle glaucoma with and without optic disc pits.

Association of Compounded Bevacizumab With Postinjection Endophthalmitis

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1159-1164. doi:10.1001/jamaophthalmol.2015.2556

This national cohort analysis of insurance claims data assesses the risk of developing endophthalmitis in a population of patients receiving intravitreal injections of repackaged bevacizumab compared with injections of single-use vials of ranibizumab.

Posterior Scleral Bowing With Choroidal Nevus on Enhanced-Depth Imaging Optical Coherence Tomography

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1165-1170. doi:10.1001/jamaophthalmol.2015.2677

This observational case series reports that choroidal nevus can show focal posterior scleral bowing on enhanced-depth imaging optical coherence tomography in 5% of cases.

Association Between Vitamin D Status and Age-Related Macular Degeneration by Genetic Risk

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1171-1179. doi:10.1001/jamaophthalmol.2015.2715

This study of postmenopausal women reports that age-related macular degeneration odds were highest in those with deficient vitamin D status and 2 risk alleles for the CFH and CFI genotypes, suggesting a synergistic effect between vitamin D status and complement cascade protein function.

Brief Report

Long-term Results of Pediatric Cataract Surgery and Primary Intraocular Lens Implantation From 7 to 22 Months of Life

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1180-1183. doi:10.1001/jamaophthalmol.2015.2062

This review evaluates the long-term outcomes of pediatric cataract surgery and primary intraocular lens implantation in children aged 7 to 22 months.

Association of Rivaroxaban Anticoagulation and Spontaneous Vitreous Hemorrhage

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1184-1186. doi:10.1001/jamaophthalmol.2015.2069

This case series explores the association between rivaroxaban anticoagulation and spontaneous vitreous hemorrhage.

Risk of Angle-Closure Glaucoma With Bupropion and Topiramate

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1187-1189. doi:10.1001/jamaophthalmol.2015.2180

This nested case-control study investigates the association of angle-closure glaucoma with buproprion and topiramate.

Association of Systemic Lupus Erythematosus With Uveitis

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1190-1193. doi:10.1001/jamaophthalmol.2015.2249

This literature review estimates the prevalence of systemic lupus erythematosus as a cause of uveitis.

Transient Macular Edema After Intracameral Injection of a Moderately Elevated Dose of Cefuroxime During Phacoemulsification Surgery

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1194-1197. doi:10.1001/jamaophthalmol.2015.2421

This case series documents an association between injection of an elevated dose of cefuroxime and transient macular edema and diminished visual acuity.

Cone and Rod Loss in Stargardt Disease Revealed by Adaptive Optics Scanning Light Ophthalmoscopy

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1198-1203. doi:10.1001/jamaophthalmol.2015.2443

This case report examines the use of adaptive optics scanning light ophthalmoscopy in characterizing Stargardt disease.

Invited Commentary

Intraoperative Optical Coherence Tomography: Ocular Surgery on a Higher Level or Just Nice Pictures?

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1133-1134. doi:10.1001/jamaophthalmol.2015.2396
JAMA Ophthalmology Clinical Challenge

Under the Guise of Retinitis

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1205-1206. doi:10.1001/jamaophthalmol.2015.1926

A man in his 30s with recent diagnosis of human immunodeficiency virus infection presents with a 5-day history of bilateral redness, blurred vision, and photophobia. What would you do next?

Vision Loss and Paresthesias in a Young Man

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1207-1208. doi:10.1001/jamaophthalmol.2015.1935

A young man presented with a 1-day history of vision loss in the left eye, eye redness for 1 week, a mild posterior headache, and tingling and numbness of the left thumb and index and middle fingers. What would you do next?

Research Letter

Association of Pretreatment With Antifungal Medication and Fungal Resistance in the Mycotic Ulcer Treatment Trial I

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1210-1211. doi:10.1001/jamaophthalmol.2015.2040

This study evaluates whether pretreatment with antifungal medications has an effect on fungal resistance in fungal ulcers.

Optical Coherence Tomographic Angiography of Choroidal Neovascularization Associated With Central Serous Chorioretinopathy

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1212-1214. doi:10.1001/jamaophthalmol.2015.2126

This case report describes the use of optical coherence tomographic angiography to detect choroidal neovascularization.

Outcomes of an Algorithmic Approach to Treating Mild Ocular Alkali Burns

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):1214-1216. doi:10.1001/jamaophthalmol.2015.2302

This case series evaluates the results of following a clinical algorithm to treat mild ocular alkali burns.

Observation

Bilateral, Multiple, Episodic Retinal Vein Occlusions Associated With Common Variable Immunodeficiency

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1216-1218. doi:10.1001/jamaophthalmol.2015.2414

This case report describes a patient with common variable immunodeficiency who developed bilateral, multiple, episodic retinal vein occlusions.

Memantine-Associated Corneal Endothelial Dysfunction

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1218-1220. doi:10.1001/jamaophthalmol.2015.2476

This case report describes corneal endothelial dysfunction in a patient being treated with memantine for Alzheimer disease.

Ophthalmic Images

Hypertensive Retinopathy, Choroidopathy, and Optic Neuropathy

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):e151494. doi:10.1001/jamaophthalmol.2015.1494

This case report describes retinopathy, choroidopathy, and optic neuropathy in a man in his late 20s with severe hypertension with resultant renal failure, congestive heart failure, and bilateral vision loss.

Burrow in the Sphenoid: A Clue to Occult Pulmonary Tuberculosis

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):e151498. doi:10.1001/jamaophthalmol.2015.1498

This case report describes an otherwise healthy man in his early 20s with a chronic, intermittently discharging, nonhealing sinus over the left upper eyelid of about 3 months’ duration.

Severe Vision Loss With Optic Disc Neovascularization After Hemiretinal Vascular Obstruction Associated With Optic Disc Melanocytoma

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):e151502. doi:10.1001/jamaophthalmol.2015.1502

This case report describes a woman in her early 40s with a history of optic disc melanocytoma who experienced acute vision loss to hand-motions level secondary to acute hemiretinal vascular occlusion.

Retinal Flecks in Primary Hyperoxaluria

Abstract Full Text
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JAMA Ophthalmol. 2015;133(10):e151532. doi:10.1001/jamaophthalmol.2015.1532

This case report describes a man in his late teens with primary hyperoxaluria presented with floaters in both eyes.

Comment & Response

Temporal Artery Biopsy in Giant Cell Arteritis

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1220. doi:10.1001/jamaophthalmol.2015.2552

Temporal Artery Biopsy in Giant Cell Arteritis—Reply

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1220-1221. doi:10.1001/jamaophthalmol.2015.2554

Considerations for Randomizing 1 Eye or 2 Eyes

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1221. doi:10.1001/jamaophthalmol.2015.2757

Considerations for Randomizing 1 Eye or 2 Eyes—Reply

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1221. doi:10.1001/jamaophthalmol.2015.2759

Teleretinal Screening for Diabetic Retinopathy

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1221-1222. doi:10.1001/jamaophthalmol.2015.2872

Teleretinal Screening for Diabetic Retinopathy—Reply

Abstract Full Text
JAMA Ophthalmol. 2015;133(10):1222. doi:10.1001/jamaophthalmol.2015.2874
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2015;133(10):1102. doi:10.1001/jamaophthalmol.2014.3743
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