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November 2015, Vol 133, No. 11, Pages 1235-1365

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1235. doi:10.1001/jamaophthalmol.2014.3747
Original Investigation

Changes in Lateral Comitance After Asymmetric Horizontal Strabismus Surgery

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1241-1246. doi:10.1001/jamaophthalmol.2015.2721

This study identifies the surgical procedures associated with changes of alignment in side gaze to help inform surgical planning for patients with horizontal strabismus.

A Proposed Minimum Standard Set of Outcome Measures for Cataract Surgery

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JAMA Ophthalmol. 2015;133(11):1247-1252. doi:10.1001/jamaophthalmol.2015.2810

This study describes the development of a minimum standard set of patient-centered outcomes for cataract surgery that allows global comparison of outcomes.

Journal Club

Treatment Effect and Corneal Light Scattering With 2 Corneal Cross-linking Protocols: A Randomized Clinical Trial

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JAMA Ophthalmol. 2015;133(11):1254-1260. doi:10.1001/jamaophthalmol.2015.2852

This randomized clinical trial evaluates the effects of 2 methods to indirectly quantify the treatment effect of corneal cross-linking in patients with progressive keratoconus.

Evaluation of Temporal Association Between Vaccinations and Retinal Hemorrhage in Children

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1261-1265. doi:10.1001/jamaophthalmol.2015.2868

This cohort study among 5177 infants and young children undergoing a dilated fundus examination as an outpatient for any reason describes the prevalence and causes of retinal hemorrhage and found no temporal association between vaccination and retinal hemorrhage.

Extent of Exacerbation of Chronic Health Conditions by Visual Impairment in Terms of Health-Related Quality of Life

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JAMA Ophthalmol. 2015;133(11):1267-1275. doi:10.1001/jamaophthalmol.2015.3055

This cross-sectional study investigates whether the impact of chronic health conditions on health-related quality of life varies according to the presence of visual impairment.

Endothelial Survival After Descemet Membrane Endothelial Keratoplasty: Effect of Surgical Indication and Graft Adherence Status

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JAMA Ophthalmol. 2015;133(11):1277-1285. doi:10.1001/jamaophthalmol.2015.3064

This cross-sectional study determines the longevity of Descemet membrane endothelial keratoplasty grafts in terms of endothelial survival and endothelial failure.

Journal Club

Relationship Between Female Reproductive Factors and Choroidal Nevus in US Women: Analysis of Data From the 2005-2008 National Health and Nutrition Examination Survey

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1287-1294. doi:10.1001/jamaophthalmol.2015.3178

This cross-sectional, population-based study explores the association between female reproductive factors and choroidal nevus in the US adult female population.

A Retrospective Review of Conjunctival Melanoma Presentation, Treatment, and Outcome and an Investigation of Features Associated With BRAF Mutations

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1295-1303. doi:10.1001/jamaophthalmol.2015.3200

Among 139 patients with primary conjunctival melanoma in Denmark, this population-based cohort study determined the associations of clinicopathological tumor features and treatment with local recurrence, metastasis, and mortality and determined the association of BRAF mutations with these features.

Clinical Presentation of Ocular Surface Squamous Neoplasia in Kenya

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1305-1313. doi:10.1001/jamaophthalmol.2015.3335

This multicenter study in Kenya of adults presenting with conjunctival lesions reports that with overlapping phenotypes and modest interobserver agreement, ocular surface squamous neoplasia and benign conjunctival lesions are not reliably distinguished clinically.

Toluidine Blue 0.05% Vital Staining for the Diagnosis of Ocular Surface Squamous Neoplasia in Kenya

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1314-1321. doi:10.1001/jamaophthalmol.2015.3345

This cross-sectional study evaluates the adverse effects, accuracy, and interobserver variation of toluidine blue 0.05% vital staining in distinguishing ocular surface squamous neoplasia from other conjunctival lesions.

Potential Effect of Tumor Necrosis Factor Inhibitors on Trabeculectomy With Mitomycin C for Patients With Juvenile Idiopathic Arthritis–Related Uveitic Glaucoma: A Retrospective Analysis

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1323-1328. doi:10.1001/jamaophthalmol.2015.3387

This observational study evaluates the potential effect of treatment with tumor necrosis factor inhibitors on the success of a trabeculectomy with mitomycin C for patients with juvenile idiopathic arthritis–related uveitic glaucoma.

Brief Report

Acute Macular Neuroretinopathy in Dengue Fever: Short-term Prospectively Followed Up Case Series

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1329-1333. doi:10.1001/jamaophthalmol.2015.2687

This case series reports that acute macular neuroretinopathy is a major manifestation of dengue maculopathy, with persistent scotomas through at least 6 months.

Exploring Sex and Laterality Imbalances in Patients Undergoing Laser Retinopexy

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1334-1336. doi:10.1001/jamaophthalmol.2015.2731

This database review reports that laser retinopexy was performed more often in males and in right eyes, suggesting that males and right eyes may have an anatomical predisposition toward retinal tears and detachment.

Macular Vascular Abnormalities Identified by Optical Coherence Tomographic Angiography in Patients With Sickle Cell Disease

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1337-1340. doi:10.1001/jamaophthalmol.2015.2824

This case series report describes the use of optical coherence tomographic angiography to identify macular vascular abnormalities in the eyes of patients with sickle cell disease.

Invited Commentary

The Universal Language of Cataract Surgery

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1253. doi:10.1001/jamaophthalmol.2015.2925

Association of Vaccinations in Young Children and Retinal Hemorrhages

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1266. doi:10.1001/jamaophthalmol.2015.3017

Vision Impairment and Chronic Health Conditions: Implications for Services

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1275-1276. doi:10.1001/jamaophthalmol.2015.3494

The Importance of Corneal Endothelial Cell Survival After Endothelial Keratoplasty

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1285-1286. doi:10.1001/jamaophthalmol.2015.3075

Conjunctival Melanoma—Clinical Pearls Now, Hope for the Future

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1303-1304. doi:10.1001/jamaophthalmol.2015.3564

Ocular Surface Squamous Neoplasia: From Blue Skies to Blue Dyes—We Still Need Our Ophthalmic Pathologists

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1321-1322. doi:10.1001/jamaophthalmol.2015.3359
Special Communication

Treatment of Retinoblastoma in 2015: Agreement and Disagreement

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1341-1347. doi:10.1001/jamaophthalmol.2015.3108

This report presents 4 collective strategies for managing intraocular retinoblastoma in leading ophthalmologic and oncologic centers.

JAMA Ophthalmology Clinical Challenge

Nystagmus in an Emaciated Infant

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1349-1350. doi:10.1001/jamaophthalmol.2015.1940

A 7-month-old boy presents with an emaciated appearance and monocular nystagmus, with no associated strabismus, head nodding, or torticollis. What Would You Do Next?

Management of Choroidal Granulomas Involving the Macula in Corticosteroid-Intolerant Patients

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1351-1352. doi:10.1001/jamaophthalmol.2015.1951

A man in his 40s with a history of chronic blurry vision in both eyes had latent extrapulmonary tuberculosis that had been treated with antitubercular therapy 1 year earlier. Oral prednisone provided visual improvement, but the therapy was complicated by avascular hip necrosis. What would you do next?

Research Letter

T-Lymphocyte Predominance and Cellular Atypia in Tattoo-Associated Uveitis

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1356-1357. doi:10.1001/jamaophthalmol.2015.3354

This case report describes a T-lymphocyte infiltrate and cellular atypia in a patient with tattoo-associated uveitis.

Observation

CRB1-Related Maculopathy With Cystoid Macular Edema

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1357-1360. doi:10.1001/jamaophthalmol.2015.2814

This case series describes twin sisters with cystoid macular edema related to a CRB1 mutation.

Spectral-Domain Optical Coherence Tomographic Imaging of Pigmented Retinal Pigment Epithelial Deposits in a Patient With Prolonged Minocycline Use

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1360-1362. doi:10.1001/jamaophthalmol.2015.2819

This case report describes pigmented deposits in the eyes of a patient with prolonged use of minocycline for acne rosacea.

Reopening of a Full-Thickness Macular Hole 2 Years After Pharmacologic Closure With Ocriplasmin

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1362-1364. doi:10.1001/jamaophthalmol.2015.3331

This case report describes the reopening of a macular hole following prior closure with ocriplasmin.

Ophthalmic Images

Hemispheric Retinal Arteriovenous Anastomoses: (Wyburn-Mason Syndrome)

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):e151687. doi:10.1001/jamaophthalmol.2015.1687

This case report describes a retinal vascular malformation (retinal arteriovenous anastomoses) that was most consistent with Wyburn-Mason syndrome.

Polypoidal Choroidal Vasculopathy: Imaging by Indocyanine Green Angiography and En Face Optical Coherence Tomography

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):e151886. doi:10.1001/jamaophthalmol.2015.1886

This case report describes polypoidal choroidal vasculopathy imaged by indocyanine green angiography and en face optical coherence tomography.

Enhanced Depth Imaging Optical Coherence Tomography of Endogenous Fungal Chorioretinitis

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):e151931. doi:10.1001/jamaophthalmol.2015.1931

This case report describes findings in a patient with endogenous fungal chorioretinitis.

Myopic Cleavage of Retinal Nerve Fiber Layer Assessed by Split-Spectrum Amplitude-Decorrelation Angiography Optical Coherence Tomography

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):e152143. doi:10.1001/jamaophthalmol.2015.2143

This case report describes a man in his 50s with primary open-angle glaucoma and myopic cleavage of the retinal nerve fiber layer.

Comment & Response

Glaucoma Surgery and Anticoagulant Therapy

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1364-1365. doi:10.1001/jamaophthalmol.2015.3071

Eye Bank Association of America Medical Standards Regarding Ebola Policy

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1364. doi:10.1001/jamaophthalmol.2015.3127

Glaucoma Surgery and Anticoagulant Therapy—Reply

Abstract Full Text
JAMA Ophthalmol. 2015;133(11):1365. doi:10.1001/jamaophthalmol.2015.3073
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2015;133(11):1239. doi:10.1001/jamaophthalmol.2014.3748
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