February 2015, Vol 133, No. 2, Pages 119-233

With the use of multistate models, the Beaver Dam Eye Study reports that the severity of age-related macular degeneration in 1 eye tracks the severity of age-related macular degeneration in its fellow eye.

This molecular genetics, observational case study reports that deleterious mutations in RAB28 result in a classic cone-rod dystrophy phenotype and are an infrequent cause of cone-rod dystrophy in the Spanish population.

This prospective cohort study reports that urinary β2-microglobulin and serum creatinine levels are sensitive diagnostic screening tools for detecting renal dysfunction to diagnose tubulointerstitial nephritis and uveitis syndrome in young patients with uveitis. Rosenbaum provides a related Article .

This prospective observational study reports that the width of the filtration opening, in patients with open-angle glaucoma who underwent uncombined fornix-based trabeculectomy, at 0.5 months posttrabeculectomy correlated with the intraocular pressure at 12 months.

This study presents the clinical differences between type I and type II Usher syndrome and between the 2 most frequent mutations in the USH2A gene. Detailed genotype-phenotype correlations allow for a better correlation of clinical signs with a known genotype.

This retrospective international cooperative study found that most patients with primary ocular adnexal diffuse large B-cell lymphoma were seen with Ann Arbor stage IE and TNM T2 disease, with a 5-year overall survival between 2.5 and 4.5 years,

This cross-sectional study conducted in the community setting reports identification of diabetic retinopathy on screening in approximately 1 in 5 persons with diabetes.

This gene transfer study in a rat model shows that inhibiting the RhoA pathway upstream of Rho kinase with a safe gene drug could provide a new enhanced treatment for long-term management of elevated nocturnal intraocular pressure.

This retrospective cohort study reports that the use of systemic chemotherapy was not proven to prevent central nervous system lymphoma in patients with primary vitreoretinal lymphoma.

Results of a cytomegalovirus (CMV) retinitis telemedicine screening program instituted at a clinic for human immunodeficiency virus care determines that retinal photography may be used to identify disease with an immediate threat to vision.

This randomized clinical trial assesses whether selective laser trabeculoplasty is an effective therapeutic option in eyes with angle closure.