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April 2020 - January 1929

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Issue

September 2015, Vol 133, No. 9, Pages 981-1096

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):981. doi:10.1001/jamaophthalmol.2014.3737
Viewpoint

Comparative Effectiveness Trial for Diabetic Macular Edema: Three Comparisons for the Price of 1 Study From the Diabetic Retinopathy Clinical Research Network

Abstract Full Text
JAMA Ophthalmol. 2015;133(9):983-984. doi:10.1001/jamaophthalmol.2015.1880

This Viewpoint discusses the early findings of the Diabetic Retinopathy Clinical Research Network, which is comparing the effectiveness of aflibercept, bevacizumab, and ranibizumab in patients with diabetic macular edema.

Original Investigation

Cost-Related Medication Nonadherence and Cost-Saving Behaviors Among Patients With Glaucoma Before and After the Implementation of Medicare Part D

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):985-996. doi:10.1001/jamaophthalmol.2015.1671

This cross-sectional study explores whether the implementation of the 2004 to 2009 Medicare Part D prescription drug benefit affected rates of cost-related nonadherence and cost-reduction strategies in Medicare beneficiaries with and without glaucoma.

Clinical Trial

Improvement in Patient-Reported Visual Function After Ocriplasmin for Vitreomacular Adhesion: Results of the Microplasmin for Intravitreous Injection–Traction Release Without Surgical Treatment (MIVI-TRUST) Trials

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):997-1004. doi:10.1001/jamaophthalmol.2015.1746

This report of 2 randomized clinical trials investigates whether intravitreal ocriplasmin improves patient-reported visual function in those with symptomatic vitreomacular adhesion.

Effect of Behavioral Intervention on Dilated Fundus Examination Rates in Older African American Individuals With Diabetes Mellitus: A Randomized Clinical Trial

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1005-1012. doi:10.1001/jamaophthalmol.2015.1760

This randomized clinical trial investigates whether behavioral interventions may have the potential to positively affect screening for diabetic retinopathy in older African American individuals with diabetes mellitus.

Potential Role of Soluble c-Met as a New Candidate Biomarker of Metastatic Uveal Melanoma

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1013-1021. doi:10.1001/jamaophthalmol.2015.1766

This pilot study reports on the potential role of soluble c-Met as a biomarker of uveal melanoma progression in comparison with S100 and lactate dehydrogenase.

Journal Club

Incidence, Risk Factors, and Timing of Elevated Intraocular Pressure After Intravitreal Triamcinolone Acetonide Injection for Macular Edema Secondary to Retinal Vein Occlusion: SCORE Study Report 15

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1022-1029. doi:10.1001/jamaophthalmol.2015.1823

This secondary analysis of a randomized clinical trial of patients with macular edema secondary to retinal vein occlusion reports that intravitreal triamcinolone acetonide injection therapy is associated with an increased risk for intraocular pressure elevation.

Valved Glaucoma Drainage Devices in Pediatric Glaucoma: Retrospective Long-term Outcomes

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1030-1035. doi:10.1001/jamaophthalmol.2015.1856

This review determines the long-term outcomes of valved implant glaucoma drainage devices and risk factors in pediatric patients with glaucoma.

Association of Diabetic Macular Nonperfusion With Outer Retinal Disruption on Optical Coherence Tomography

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1036-1044. doi:10.1001/jamaophthalmol.2015.2183

This observational cross-sectional study evaluated outer retinal changes in areas of macular ischemia on optical coherence tomography in diabetic patients.

Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1045-1052. doi:10.1001/jamaophthalmol.2015.2225

This observational study compares peripapillary retinal perfusion in glaucomatous eyes and normal eyes using optical coherence tomography angiography.

Oxidized Low-Density Lipoprotein and the Incidence of Proliferative Diabetic Retinopathy and Clinically Significant Macular Edema Determined From Fundus Photographs

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1054-1061. doi:10.1001/jamaophthalmol.2015.2239

This study reports on whether an association exists between increasing levels of serum oxidized low-density lipoprotein and the incidence of proliferative diabetic retinopathy, the incidence of macular edema, and the worsening of diabetic retinopathy in persons with type 1 diabetes.

Enucleation vs Ophthalmic Artery Chemosurgery for Advanced Intraocular Retinoblastoma: A Retrospective Analysis

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1062-1066. doi:10.1001/jamaophthalmol.2015.2243

This cohort study evaluates the incidence of orbital recurrence of advanced-stage retinoblastoma in patients treated with enucleation vs ophthalmic artery chemosurgery.

Brief Report

Structural Abnormalities of the Inner Macula in Incontinentia Pigmenti

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1067-1072. doi:10.1001/jamaophthalmol.2015.1700

This report shows evidence of inner foveal structural abnormalities associated with vision loss in children with incontinentia pigmenti.

Variable Results for Uveal Melanoma–Specific Gene Expression Profile Prognostic Test in Choroidal Metastasis

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1073-1076. doi:10.1001/jamaophthalmol.2015.1790

This case series review reports that a gene expression profile prognostic test for choroidal metastasis may be a helpful test for molecular prognostication in patients with uveal melanoma.

Assessing the Effect of a Glaucoma Surgical Curriculum in Resident Physicians

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1077-1080. doi:10.1001/jamaophthalmol.2015.1846

This study evaluates the effect of a structured glaucoma surgical curriculum in resident physicians.

Invited Commentary

Measuring Blood Flow: So What?

Abstract Full Text
JAMA Ophthalmol. 2015;133(9):1052-1053. doi:10.1001/jamaophthalmol.2015.2287
JAMA Ophthalmology Clinical Challenge

Blurred Vision in a Woman Who Had Sphenoid Wing Meningioma

Abstract Full Text
JAMA Ophthalmol. 2015;133(9):1081-1082. doi:10.1001/jamaophthalmol.2015.1144

A woman in her early 40s with a history of recurrent meningioma of the right sphenoid wing after tumor resections, followed by adjuvant radiation, presented with fluctuating vision in the right eye for several months. Her best-corrected visual acuity was 20/20 OD and 20/20 OS. What would you do next?

Chronic Conjunctivitis and “Warts”

Abstract Full Text
JAMA Ophthalmol. 2015;133(9):1083-1084. doi:10.1001/jamaophthalmol.2015.1284

A 10-year-old boy presents with a 6-month history of intermittent redness, swelling, and itching of the right eye and multiple raised papules on the face, elbow, and knee. What Would You Do Next?

Research Letter

Acquired Combined Hamartoma of the Retina and Retinal Pigment Epithelium

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1085-1086. doi:10.1001/jamaophthalmol.2015.1675

This case report describes a patient with an acquired combined hamartoma of the retina and retinal pigment epithelium.

Retrospective Appraisal of Split-Cornea Transplantation: An Audit of 1141 Donor Corneas

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1086-1087. doi:10.1001/jamaophthalmol.2015.1684

This study evaluates split-cornea transplantation, which uses donor tissue for deep anterior lamellar keratoplasty in one patient and Descemet membrane endothelial keratoplasty in another patient.

Sequential Optical Coherence Tomographic Angiography for Diagnosis and Treatment of Choroidal Neovascularization in Multifocal Choroiditis

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1087-1090. doi:10.1001/jamaophthalmol.2015.1946

This case report describes choroidal neovascularization in multifocal choroiditis diagnosed using optical coherence tomographic angiography.

Observation

Facial Ulcers and Restrictive Strabismus From Delayed Periorbital Granuloma After Poly-l–Lactic Acid Injection

Abstract Full Text
JAMA Ophthalmol. 2015;133(9):1090-1091. doi:10.1001/jamaophthalmol.2015.1666

This case report describes facial ulcers and strabismus occurring after dermal filler injection.

Zonular Dehiscence at the Time of Combined Vitrectomy and Cataract Surgery After Intravitreal Ocriplasmin Injection

Abstract Full Text
JAMA Ophthalmol. 2015;133(9):1091-1092. doi:10.1001/jamaophthalmol.2015.1680

Diffuse Pigmentary Retinopathy and Preretinal and Perivascular Intraretinal Invasion of Choroidal Malignant Melanoma

Abstract Full Text
JAMA Ophthalmol. 2015;133(9):1092-1094. doi:10.1001/jamaophthalmol.2015.1817

This case report describes malignant melanoma with perivascular retinal invasion.

Two Distinct Uveal Melanomas in the Same Eye

Abstract Full Text
JAMA Ophthalmol. 2015;133(9):1094-1096. doi:10.1001/jamaophthalmol.2015.1962

This case report describes separate uveal melanomas in the same eye.

Ophthalmic Images

Combined Hamartoma of the Retina and Retinal Pigment Epithelium Leading to the Diagnosis of Neurofibromatosis Type 2

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):e151289. doi:10.1001/jamaophthalmol.2015.1289

This Ophthalmic Image describes a combined hamartoma of the retina and retinal pigment epithelium, which led to the diagnosis of bilateral acoustic neuromas and subsequently neurofibromatosis type 2.

Dislocated Crystalline Lens Mimicking Metastatic Endometrial Cancer

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):e151336. doi:10.1001/jamaophthalmol.2015.1336

This Ophthalmic Image describes a dislocated crystalline lens that erroneously mimicked metastatic cancer as a complication of homocystinuria.

Silicone Oil Retention Sutures for Retinal Detachment Repair Following Traumatic Aniridia, Aphakia, and Ruptured Globe

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):e151433. doi:10.1001/jamaophthalmol.2015.1433

This Ophthalmic Image describes silicone oil retention sutures for retinal detachment repair.

Hypometabolic Lateral Recti Due to Bilateral Cranial Nerve VI Palsy

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):e151490. doi:10.1001/jamaophthalmol.2015.1490

This Ophthalmic Image describes the ophthalmic findings in a patient with bilateral cranial nerve VI palsy.

Correction

Error in Text

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1096. doi:10.1001/jamaophthalmol.2015.2843

Incorrect Information and Error in Figure

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):1096. doi:10.1001/jamaophthalmol.2015.3195
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2015;133(9):982. doi:10.1001/jamaophthalmol.2014.3738
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