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February 2016, Vol 134, No. 2, Pages 121-240

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
free access
JAMA Ophthalmol. 2016;134(2):121. doi:10.1001/jamaophthalmol.2015.3214
Viewpoint

Genetic Incidentaloma in Ophthalmology

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):123-124. doi:10.1001/jamaophthalmol.2015.4679

This Viewpoint discusses “genetic incidentalomas” in ophthalmology.

Refining the Terminology of Graft Failure in Reports on Endothelial Keratoplasty Outcomes

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):125-126. doi:10.1001/jamaophthalmol.2015.5029

This Viewpoint discusses the necessity of refining the terminology used for graft survival studies.

Original Investigation

Association of Baseline Visual Acuity and Retinal Thickness With 1-Year Efficacy of Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):127-134. doi:10.1001/jamaophthalmol.2015.4599

This study uses data from a trial comparing bevacizumab, aflibercept, and ranibizumab for treatment of diabetic macular edema to report exploratory outcomes by baseline visual acuity and central subfield thickness subgroups.

Effects of Prior Intensive Insulin Therapy and Risk Factors on Patient-Reported Visual Function Outcomes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Cohort

Abstract Full Text
free access
JAMA Ophthalmol. 2016;134(2):137-145. doi:10.1001/jamaophthalmol.2015.4606

This cohort study of participants from a randomized clinical trial assesses the effects of prior intensive insulin treatment for patients with diabetes and risk factors on patient-reported visual function.

Automated Ptosis Measurements From Facial Photographs

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):146-150. doi:10.1001/jamaophthalmol.2015.4614

This observational study describes a software algorithm for determining the margin reflex distances 1 and 2 from facial photographs and evaluates its agreement with manual measurements.

Clinical Validation of a Smartphone-Based Adapter for Optic Disc Imaging in Kenya

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):151-158. doi:10.1001/jamaophthalmol.2015.4625

This diagnostic accuracy study compares the grading and quality of optic disc images taken in Kenya by an ophthalmic assistant using a desktop retinal camera vs those taken by non-clinical photographers using a smartphone-based adapter for optic disc imaging.

Effect of Ranibizumab on the Decision to Drive and Vision Function Relevant to Driving in Patients With Diabetic Macular Edema: Report From RESTORE, RIDE, and RISE Trials

Abstract Full Text
free access
JAMA Ophthalmol. 2016;134(2):160-166. doi:10.1001/jamaophthalmol.2015.4636

This exploratory post hoc analysis of 3 randomized clinical trials suggests that 12 months after initiating ranibizumab for vision impairment, patients with diabetic macular edema not driving at initiation of treatment are more likely to report driving and have driving-eligible visual acuity of 20/40 or better in the better-seeing eye than those treated with sham or laser.

Global Survey of Corneal Transplantation and Eye Banking

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):167-173. doi:10.1001/jamaophthalmol.2015.4776

This survey assesses the worldwide supply and demand of corneal transplantation.

Hepatic Ultrasonography for Surveillance in Patients With Uveal Melanoma

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):174-180. doi:10.1001/jamaophthalmol.2015.4810

This cohort study evaluates the use of serial hepatic ultrasonography in detecting asymptomatic liver metastases in patients with uveal melanoma.

Correlation of 3-Dimensionally Quantified Intraretinal and Subretinal Fluid With Visual Acuity in Neovascular Age-Related Macular Degeneration

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):182-190. doi:10.1001/jamaophthalmol.2015.4948

This cohort study examines the correlations between intraretinal cystoid fluid and subretinal fluid parameters and visual acuity in patients with neovascular age-related macular degeneration.

Concentration Accuracy of Compounded Mitomycin C for Ophthalmic Surgery

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):191-195. doi:10.1001/jamaophthalmol.2015.4970

This laboratory study evaluated whether the measured concentration of mitomycin C differs from the expected concentration of 0.4 mg/mL used in ophthalmic surgery.

Risk of Mortality and of Atherosclerotic Events Among Patients Who Underwent Hemodialysis and Subsequently Developed Retinal Vascular Occlusion: A Taiwanese Retrospective Cohort Study

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):196-203. doi:10.1001/jamaophthalmol.2015.5052

This cohort study reports on the mortality rate and subsequent prevalence of systemic vascular diseases associated with retinal vascular occlusion among patients undergoing hemodialysis in Taiwan.

Evaluation of Automated Teleretinal Screening Program for Diabetic Retinopathy

Abstract Full Text
free access
JAMA Ophthalmol. 2016;134(2):204-209. doi:10.1001/jamaophthalmol.2015.5083

This cohort analysis evaluates the efficacy of an automated algorithm in interpreting screening ophthalmoscopic photographs from patients with diabetes compared with a reading center interpretation.

Journal Club

Variation in Prescription Drug Coverage Enrollment Among Vulnerable Beneficiaries With Glaucoma Before and After the Implementation of Medicare Part D

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):212-220. doi:10.1001/jamaophthalmol.2015.5090

This observational study uses the Medicare Current Beneficiary Survey to assess changes in prescription drug coverage and out-of-pocket spending after the implementation of Medicare Part D.

Comparison of Prevalence of Diabetic Macular Edema Based on Monocular Fundus Photography vs Optical Coherence Tomography

Abstract Full Text
free access
JAMA Ophthalmol. 2016;134(2):222-228. doi:10.1001/jamaophthalmol.2015.5332

This cross-sectional study compares the prevalence of diabetic macular edema based on monocular fundus photography vs optical coherence tomography in patients with diabetic retinopathy.

Invited Commentary

Drilling Deeper for Treatment Choices in Diabetic Macular Edema

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):135-136. doi:10.1001/jamaophthalmol.2015.4652

Applicability of Smartphone-Based Screening Programs

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):158-159. doi:10.1001/jamaophthalmol.2015.4823

Is Surveillance of Uveal Melanoma Just a Screen?

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):180-181. doi:10.1001/jamaophthalmol.2015.4817

Future Promise of and Potential Pitfalls for Automated Detection of Diabetic Retinopathy

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):210-211. doi:10.1001/jamaophthalmol.2015.5099

Effect of Medicare Part D on the Availability of Medical Treatment for Patients With Glaucoma

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):220-221. doi:10.1001/jamaophthalmol.2015.5176
Surgical Technique

Autologous Neurosensory Retinal Free Flap for Closure of Refractory Myopic Macular Holes

Abstract Full Text
free access has multimedia
JAMA Ophthalmol. 2016;134(2):229-230. doi:10.1001/jamaophthalmol.2015.5237

This Surgical Technique describes the use of an autologous neurosensory retinal free flap for closure of refractory myopic macular holes with associated foveoschisis and/or retinal detachment.

JAMA Ophthalmology Clinical Challenge

Recurrent Vitreous Hemorrhage Despite Pars Plana Vitrectomy, Laser, and Injections

Abstract Full Text
has multimedia
JAMA Ophthalmol. 2016;134(2):231-232. doi:10.1001/jamaophthalmol.2015.2136

A man in his 60s had sudden-onset blurry vision in the right eye secondary to vitreous hemorrhage and dry cough. Careful examination revealed a dislocated haptic of the single-piece intraocular lens inferonasally with a small radial tear in the anterior capsule in the right eye. What would you do next?

Painful Red Eye in a Woman in Her 70s

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):233-234. doi:10.1001/jamaophthalmol.2015.2152

A woman in her 70s presented with an 8-day history of worsening pain and redness of the right eye. What would you do next?

Acute Bilateral Vision Loss

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):235-236. doi:10.1001/jamaophthalmol.2015.3572

A man in his 60s with a history of untreated, indolent B-cell lymphoma diagnosed 8 years ago noted acute-onset blurred vision in both eyes. What would you do next?

Ophthalmic Images

Legal Blindness From Severe Optic Nerve Head Drusen

Abstract Full Text
online only
JAMA Ophthalmol. 2016;134(2):e153660. doi:10.1001/jamaophthalmol.2015.3660

This Ophthalmic Image shows fundus autofluorescence imaging and optical coherence tomography of severe optic nerve head drusen.

Ocular Surface Squamous Neoplasia

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):e153666. doi:10.1001/jamaophthalmol.2015.3666

This Ophthalmic Image shows a gelatinous limbal mass lesion before and after treatment with topical mitomycin C.

Two-Year Follow-up of a Prepapillary Vascular Loop–Related Branch Retinal Artery Occlusion

Abstract Full Text
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JAMA Ophthalmol. 2016;134(2):e153670. doi:10.1001/jamaophthalmol.2015.3670

This Ophthalmic Image shows a prepapillary vascular loop in a teenage boy.

Glaucoma Tube Changes After Suture Lysis Assessed by High-Resolution Anterior Segment Optical Coherence Tomography

Abstract Full Text
online only
JAMA Ophthalmol. 2016;134(2):e153674. doi:10.1001/jamaophthalmol.2015.3674

This Ophthalmic Image shows swept-source optical coherence tomography of glaucoma tube changes after Baerveldt glaucoma implant into the ciliary sulcus.

Comment & Response

Is Saturday Night Retinopathy Being Reported More Frequently?

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):238. doi:10.1001/jamaophthalmol.2015.4819

Long-term Risk of Melanoma-Related Mortality After Uveal Melanoma

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):238-239. doi:10.1001/jamaophthalmol.2015.5233

Long-term Risk of Melanoma-Related Mortality After Uveal Melanoma—Reply

Abstract Full Text
JAMA Ophthalmol. 2016;134(2):239-240. doi:10.1001/jamaophthalmol.2015.5235
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2016;134(2):122. doi:10.1001/jamaophthalmol.2015.3215
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