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August 2019 - January 1929

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Issue

April 2016, Vol 134, No. 4, Pages 349-469

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
free access
JAMA Ophthalmol. 2016;134(4):349. doi:10.1001/jamaophthalmol.2015.3226
Viewpoint

Increasing the Availability and Quality of Donor Eyes for Research

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):351-352. doi:10.1001/jamaophthalmol.2015.5492

This Viewpoint discusses the need to ameliorate the shortage of donor eyes and increase the quality of human tissues available for scientific inquiry.

The US Food and Drug Administration’s New Regulatory Toolkit to Bring Medical Device Innovation Back to the United States

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):353-354. doi:10.1001/jamaophthalmol.2015.5943

This Viewpoint reports on the US Food and Drug Administration’s commitment to promoting public health by facilitating the development of innovative medical devices.

Terminology of MCDR1: What’s in a Name?

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):355-356. doi:10.1001/jamaophthalmol.2015.4978

This Viewpoint describes the terminology of the disease MCDR1, also called North Carolina macular dystrophy.

Original Investigation

Self-reported Function, Health Resource Use, and Total Health Care Costs Among Medicare Beneficiaries With Glaucoma

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):357-365. doi:10.1001/jamaophthalmol.2015.5479

This longitudinal observational study using the Medicare Current Beneficiary Survey assesses self-reported medical conditions, the use of medical services, and total health care costs among Medicare beneficiaries with glaucoma.

Automated Quantification of Capillary Nonperfusion Using Optical Coherence Tomography Angiography in Diabetic Retinopathy

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):367-373. doi:10.1001/jamaophthalmol.2015.5658

This observational study compares optical coherence tomography angiography with fluorescein angiography for quantification of capillary nonperfusion in eyes of patients with diabetic retinopathy.

Measured Changes in Limbal Strain During Simulated Sleep in Face Down Position Using an Instrumented Contact Lens in Healthy Adults and Adults With Glaucoma

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):375-382. doi:10.1001/jamaophthalmol.2015.5667

This case-control study measures strains in glaucoma eyes and control eyes produced by mechanical force or deformation of the eye from contact when one side of the face rests against a pillow.

Association of Biofilm Formation, Psl Exopolysaccharide Expression, and Clinical Outcomes in Pseudomonas aeruginosa Keratitis: Analysis of Isolates in the Steroids for Corneal Ulcers Trial

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):383-389. doi:10.1001/jamaophthalmol.2015.5956

This study examines whether in vitro biofilm formation and Psl exopolysaccharide expression are associated with clinical presentation or outcomes in Pseudomonas aeruginosa keratitis.

Association of Radiation Dose to the Eyes With the Risk for Cataract After Nonretinoblastoma Solid Cancers in Childhood

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):390-397. doi:10.1001/jamaophthalmol.2015.6088

This cohort stucy assesses the role of radiation dose in the risk for cataract in a population of survivors of childhood nonretinoblastoma solid cancer.

Development of a Reading Accessibility Index Using the MNREAD Acuity Chart

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):398-405. doi:10.1001/jamaophthalmol.2015.6097

This study compares the Reading Accessibility Index with data from the Impact of Cataracts on Mobility study among individuals with cataract, pseudophakia, or natural crystalline lenses.

Conjunctival Lymphoma—An International Multicenter Retrospective Study

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):406-414. doi:10.1001/jamaophthalmol.2015.6122

This multicenter study characterizes subtype-specific clinical features of conjunctival lymphoma and their effect on patient outcome.

Association Between Oral Fluoroquinolone Use and Retinal Detachment

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):415-421. doi:10.1001/jamaophthalmol.2015.6205

This case-crossover study uses data from the French National Interscheme Health Insurance Information System to investigate the association of fluoroquinolone exposure and retinal detachment in a French population of patients undergoing surgery for retinal detachment.

Journal Club

Awareness and Knowledge of Emergent Ophthalmic Disease Among Patients in an Internal Medicine Clinic

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):424-431. doi:10.1001/jamaophthalmol.2015.6212

This cross-sectional study assesses patient awareness and knowledge of 4 emergent ophthalmic diseases among patients presenting to an internal medicine clinic.

The Effect of Light Exposure on the Efficacy and Safety of Amphotericin B in Corneal Storage Media

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):432-436. doi:10.1001/jamaophthalmol.2016.0008

This in vitro laboratory study assesses the efficacy of amphotericin B supplementation in Optisol-GS for elimination of Candida albicans contaminants from commercially available corneal storage medium without toxic effects to the cornea.

Topical Dorzolamide-Timolol With Intravitreous Anti–Vascular Endothelial Growth Factor for Neovascular Age-Related Macular Degeneration

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):437-443. doi:10.1001/jamaophthalmol.2016.0045

This exploratory study evaluates the effect of topical dorzolamide hydrochloride–timolol maleate on anatomic and functional outcomes in eyes with neovascular age-related macular degeneration and incomplete response to anti–vascular endothelial growth factor therapy.

Brief Report

Precision Medicine: Personalized Proteomics for the Diagnosis and Treatment of Idiopathic Inflammatory Disease

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):444-448. doi:10.1001/jamaophthalmol.2015.5934

This case report and analysis of vitreous samples investigates a common cytokine signature for posterior uveitis and use of proteomic tools in patients with idiopathic disease.

Toxic Keratopathy Following the Use of Alcohol-Containing Antiseptics in Nonocular Surgery

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):449-452. doi:10.1001/jamaophthalmol.2016.0001

This case report discusses the development of toxic keratopathy following the use of alcohol-containing antiseptic solutions in nonocular surgery.

Invited Commentary

Uncovering Some of the Hidden Costs and Burdens of Glaucoma

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):365-366. doi:10.1001/jamaophthalmol.2015.5488

Optical Coherence Tomographic Angiography in Diabetic Macular Ischemia: A New Step Forward

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):373-374. doi:10.1001/jamaophthalmol.2015.4821

Oral Fluoroquinolones, Retinal Detachments, and Claims Database Studies

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):422-423. doi:10.1001/jamaophthalmol.2016.0240
JAMA Ophthalmology Clinical Challenge

Angiographically Silent Macular Edema

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):453-454. doi:10.1001/jamaophthalmol.2015.3614

A man in his late 70s presented with a 1-month history of blurry vision in his left eye and reported fatigue, muscle stiffness, joint pain, and unintentional weight loss.What would you do next?

Chronic Recurrent Pseudophakic Endophthalmitis

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):455-456. doi:10.1001/jamaophthalmol.2015.3638

A woman in her 80s underwent uncomplicated cataract surgery but developed recurrent pseudophakic endophthalmitis. What would you do next?

Acute Increase in Intraocular Pressure in a Patient With a Glaucoma Drainage Implant

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):457-458. doi:10.1001/jamaophthalmol.2015.3642

A woman with a glaucoma drainage implant presents with severe right eye pain, a headache, and increased intraocular pressure. What would you do next?

Retinal Rings

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):459-460. doi:10.1001/jamaophthalmol.2015.3646

A woman in her early 80s with a history of systemic hypertension and heart failure presents with retinal changes, including an annular area of hypopigmentation, in both eyes. What would you do next?

Observation

Omalizumab Treatment of Vernal Keratoconjunctivitis

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):461-463. doi:10.1001/jamaophthalmol.2015.5679

This report describes 2 patients with vernal keratoconjunctivitis without concomitant asthma who underwent systemic treatment with omalizumab.

Central Retinal Vein Occlusion Noted 2 Days After Use of Phendimetrazine as an Appetite Suppressant

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):463-464. doi:10.1001/jamaophthalmol.2015.5966

A woman in her 40s had sudden painless loss of vision in her left eye for 3 days. Fluorescein angiography revealed nonischemic central retinal vein occlusion of her left eye.

Malignant Melanoma Presenting as Pedunculated Lesion of the Caruncle

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):464-466. doi:10.1001/jamaophthalmol.2015.6084

This case report describes malignant melanoma confined to the caruncle, without evidence of primary acquired melanosis.

Reperfusion of Retinal Vasculature With Improved Visual Acuity in Ischemic Occlusive Vasculitis

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):466-467. doi:10.1001/jamaophthalmol.2015.6164

This case report describes vascular reperfusion and visual rehabilitation with aggressive treatment for occlusive retinal vasculitis.

Bilateral Endogenous Endophthalmitis Caused by Candida albicans After Breast Implant Surgery

Abstract Full Text
JAMA Ophthalmol. 2016;134(4):467-469. doi:10.1001/jamaophthalmol.2016.0015

This case report describes a healthy woman in her 20s who manifested an elevated temperature and blurred vision in both eyes the day after breast augmentation surgery.

Correction

Error in Byline

Abstract Full Text
free access
JAMA Ophthalmol. 2016;134(4):469. doi:10.1001/jamaophthalmol.2016.0422

Error in Table

Abstract Full Text
free access
JAMA Ophthalmol. 2016;134(4):469. doi:10.1001/jamaophthalmol.2016.0428
Ophthalmic Images

Retinal Tear Related to Air Bag Deployment

Abstract Full Text
online only
JAMA Ophthalmol. 2016;134(4):e155021. doi:10.1001/jamaophthalmol.2015.5021

This Ophthalmic Image shows ultra–wide-field retinal imaging of a retinal tear resulting from air bag deployment during a motor vehicle crash.

Spontaneous Extrusion of Subconjunctival Cysticercosis Cyst

Abstract Full Text
online only
JAMA Ophthalmol. 2016;134(4):e155025. doi:10.1001/jamaophthalmol.2015.5025

This Ophthalmic Image shows a subconjunctival cystic mass that spontaneously egressed at the time of slitlamp examination.

Ultra–Wide-Field Autofluorescence in Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency Chorioretinopathy

Abstract Full Text
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JAMA Ophthalmol. 2016;134(4):e155033. doi:10.1001/jamaophthalmol.2015.5033

This Ophthalmic Image shows ultra–wide-field autofluorescence findings in a patient with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency chorioretinopathy.

Branch Retinal Artery Occlusion Imaged With Spectral-Domain Optical Coherence Tomographic Angiography

Abstract Full Text
online only
JAMA Ophthalmol. 2016;134(4):e155041. doi:10.1001/jamaophthalmol.2015.5041

This case report describes a man in his early 80s presented with 2-day history of sudden onset of visual field loss above fixation in the right eye.

JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2016;134(4):350. doi:10.1001/jamaophthalmol.2015.3227
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