Sheila K. West, PhD; Andrea I. Zambrano, MD; Shekhar Sharma, BS; et al.
free access
JAMA Ophthalmol. 2017;135(11):1141-1146. doi:10.1001/jamaophthalmol.2017.3062
This study of cross-sectional surveys administered in 2015 and 2016 determines the prevalence of trachoma among 4 districts in Nepal that each had surveillance intervals of 2, 4, 8, and 10 years after cessation of mass drug administration.
Cynthia Yu-Wai-Man, PhD, FRCOphth; Aristides D. Tagalakis, PhD; Jinhong Meng, PhD; et al.
free access
JAMA Ophthalmol. 2017;135(11):1147-1155. doi:10.1001/jamaophthalmol.2017.3407
This cross-sectional study compares the clinical phenotype of patients with conjunctival fibrosis after glaucoma surgery with candidate gene expression tissue biomarkers of fibrosis.
James T. Rosenbaum, MD; Dongseok Choi, PhD; Christina A. Harrington, PhD; et al.
free access
has multimedia
JAMA Ophthalmol. 2017;135(11):1156-1162. doi:10.1001/jamaophthalmol.2017.3458
This cohort study tests the a priori hypothesis that gene expression profiles would complement clinical and histopathologic evaluations in identifying well-characterized diseases and in subdividing nonspecific orbital inflammation into clinically relevant groups.
Maria P. Fernandez, MD; Edgar Parra Saad, MD; Martha Ospina Martinez, MD; et al.
free access
has audio
JAMA Ophthalmol. 2017;135(11):1163-1169. doi:10.1001/jamaophthalmol.2017.3595
This case series evaluates the presence of Zika virus antigens and describes the associated ocular histopathologic features of 4 cases of congenital Zika syndrome.
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Audio Author Interview:
Ocular Histopathologic Features of Congenital Zika Syndrome
Philippe M. Burlina, PhD; Neil Joshi, BS; Michael Pekala, MS; et al.
free access
JAMA Ophthalmol. 2017;135(11):1170-1176. doi:10.1001/jamaophthalmol.2017.3782
This study uses deep learning methods for the automated assessment of age-related macular degeneration from color fundus images.
Sun Young Lee, MD, PhD; Justine L. Cheng, AB; Karen M. Gehrs, MD; et al.
free access
JAMA Ophthalmol. 2017;135(11):1177-1183. doi:10.1001/jamaophthalmol.2017.3790
This case series describes initial and serial multimodal imaging findings in acute macular neuroretinopathy with attention to choroidal vascular changes.
Kimberly M. Brothers, PhD; Robert M. Q. Shanks, PhD; Susan Hurlbert, CEBT; et al.
free access
JAMA Ophthalmol. 2017;135(11):1184-1190. doi:10.1001/jamaophthalmol.2017.3797
This study determines whether eye bank–processed endothelial keratoplasty tissue is at higher risk of contamination than unprocessed tissue.
Thanos D. Papakostas, MD; Anne Marie Lane, MPH; Margaux Morrison, MPH; et al.
free access
JAMA Ophthalmol. 2017;135(11):1191-1196. doi:10.1001/jamaophthalmol.2017.3805
This single-center cohort study analyzes 10-year outcomes of visual acuity, eye retention, development of neovascular glaucoma, tumor recurrence, and melanoma-related mortality in patients who underwent proton beam irradiation for large choroidal melanomas.
Akihito Uji, MD, PhD; Siva Balasubramanian, MD, PhD; Jianqin Lei, MD; et al.
free access
has multimedia
JAMA Ophthalmol. 2017;135(11):1197-1204. doi:10.1001/jamaophthalmol.2017.3904
This cross-sectional case series investigates multiple en face image averaging for optical coherence tomography angiography images of the choriocapillaris.
Adrian Koh, MD, FRCS; Timothy Y. Y. Lai, MD, FRCS; Kanji Takahashi, MD; et al.
open access
has multimedia
JAMA Ophthalmol. 2017;135(11):1206-1213. doi:10.1001/jamaophthalmol.2017.4030
This randomized clinical trial compares the efficacy and safety of combination therapy of ranibizumab and verteporfin photodynamic therapy with ranibizumab monotherapy in polypoidal choroidal vasculopathy.
Shriji Patel, MD; Paul Sternberg Jr, MD
free access
JAMA Ophthalmol. 2017;135(11):1216-1220. doi:10.1001/jamaophthalmol.2017.4055
This observational cohort study determines the opioid prescribing patterns among ophthalmologists and elucidates ophthalmologists’ role in the prescription opioid abuse epidemic.
Jesse L. Berry, MD; Liya Xu, PhD; A. Linn Murphree, MD; et al.
free access
JAMA Ophthalmol. 2017;135(11):1221-1230. doi:10.1001/jamaophthalmol.2017.4097
This case series study investigates whether the aqueous humor of retinoblastoma eyes has sufficient tumor-derived DNA to perform genetic analysis of the tumor, including DNA copy number alterations.
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Invited Commentary
Liquid Biopsy in Retinoblastoma
J. William Harbour, MD
Rupert W. Strauss, MD; Beatriz Muñoz, MS; Alexander Ho, BSE; et al.
free access
JAMA Ophthalmol. 2017;135(11):1232-1241. doi:10.1001/jamaophthalmol.2017.4152
This multicenter cohort study describes the yearly progression rate of atrophic lesions as determined by fundus autofluorescence in the retrospective Progression of Stargardt Disease study.
Stuart Keel, PhD; Jing Xie, PhD; Joshua Foreman, BSci (Hons); et al.
free access
JAMA Ophthalmol. 2017;135(11):1242-1249. doi:10.1001/jamaophthalmol.2017.4182
This study examines the prevalence of age-related macular degeneration in Australia.
Sarah Read-Brown, BA; Michelle R. Hribar, PhD; Leah G. Reznick, MD; et al.
free access
JAMA Ophthalmol. 2017;135(11):1250-1257. doi:10.1001/jamaophthalmol.2017.4187
This single-center cohort study examines ophthalmologist time requirements for electronic health record use.
Jean-François Korobelnik, MD; Marie-Bénédicte Rougier, MD, PhD; Marie-Noëlle Delyfer, MD, PhD; et al.
free access
JAMA Ophthalmol. 2017;135(11):1259-1266. doi:10.1001/jamaophthalmol.2017.3398
This randomized clinical trial estimates the efficiency of dietary supplementation containing lutein, zeaxanthin, ω-3 polyunsaturated fatty acids, and vitamins to increase the density of macular pigment in first-generation offspring of parents with neovascular age-related macular degeneration.