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May 2019 - January 1929

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Issue

April 2017, Vol 135, No. 4, Pages 297-404

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):297. doi:10.1001/jamaophthalmol.2016.3727
Original Investigation

Incidence of and Risk Factors for Developing Idiopathic Macular Hole Among a Diverse Group of Patients Throughout the United States

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):299-305. doi:10.1001/jamaophthalmol.2016.5870

This longitudinal cohort study examines the incidence of and risk factors associated with the development of idiopathic macular hole requiring surgical repair with vitrectomy among a large group of US managed care plan beneficiaries.

Journal Club

Optical Coherence Tomographic Angiography in Type 2 Diabetes and Diabetic Retinopathy

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):306-312. doi:10.1001/jamaophthalmol.2016.5877

This cohort study evaluates the retinal microvasculature using optical coherence tomographic angiography in patients with diabetes as well as the association of optical coherence tomographic angiography characteristics with diabetic retinopathy and systemic risk factors.

Intraobserver and Interobserver Agreement of Structural and Functional Software Programs for Measuring Glaucoma Progression

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):313-319. doi:10.1001/jamaophthalmol.2017.0017

This study evaluates the agreement in visual field testing and optical coherence tomography software among 5 glaucoma specialists.

Evaluation of Optical Coherence Tomography to Detect Elevated Intracranial Pressure in Children

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):320-328. doi:10.1001/jamaophthalmol.2017.0025

This cross-sectional study evaluates whether retinal measurements from optical coherence tomography can serve as an effective surrogate for invasive intracranial pressure measurement.

Journal Club

Association of Maternal Smoking During Pregnancy and Birth Weight With Retinal Nerve Fiber Layer Thickness in Children Aged 11 or 12 Years: The Copenhagen Child Cohort 2000 Eye Study

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):331-337. doi:10.1001/jamaophthalmol.2017.0043

This study describes the association of mothers’ tobacco smoking during pregnancy and children’s low birth weight with the retinal nerve fiber layer thickness in Danish children.

Association of Steroid 5α-Reductase Type 3 Congenital Disorder of Glycosylation With Early-Onset Retinal Dystrophy

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):339-347. doi:10.1001/jamaophthalmol.2017.0046

This case series reports on the SRD5A3 gene mutation that causes early-onset retinal dystrophy.

Association of Pseudoexfoliation With Systemic Vascular Diseases in a South Indian Population

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):348-354. doi:10.1001/jamaophthalmol.2017.0064

This cross-sectional postoperative study assesses whether prespecified vascular risk factors and cardiac abnormalities are more common among patients in Southern India with vs without pseudoexfoliation presenting for cataract surgery.

Human Leukocyte Antigen Class I Genes Associated With Stevens-Johnson Syndrome and Severe Ocular Complications Following Use of Cold Medicine in a Brazilian Population

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):355-360. doi:10.1001/jamaophthalmol.2017.0074

This case-control study examines class I human leukocyte antigens in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis with severe ocular complications who were using cold medicines near the time of the disease onset.

Association of Repeated Intravitreous Bevacizumab Injections With Risk for Glaucoma Surgery

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):363-368. doi:10.1001/jamaophthalmol.2017.0059

This case-control study uses data from the British Columbia Ministry of Health databases to assess the effect of recurring intravitreous bevacizumab injections with the need for glaucoma surgery.

Quantification of Retinal Microvascular Density in Optical Coherence Tomographic Angiography Images in Diabetic Retinopathy

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):370-376. doi:10.1001/jamaophthalmol.2017.0080

This cross-sectional study evaluates the ability of measurements of retinal microvasculature using optical coherence tomographic angiography to distinguish healthy eyes from eyes with diabetic retinopathy.

Brief Report

Incidence and Visual Outcomes of Culture-Proven Endophthalmitis Following Dexamethasone Intravitreal Implant

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):379-382. doi:10.1001/jamaophthalmol.2016.5883

This single-center case series reports the incidence of culture-proven endophthalmitis over the course of 3 years and describes the clinical outcomes associated with each case of endophthalmitis.

Treatment of Ocular Pyogenic Granuloma With Topical Timolol

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):383-385. doi:10.1001/jamaophthalmol.2017.0110

This case series investigates whether ocular surface pyogenic granulomas resolve with topical β-blocker therapy.

Chorioretinal Lesions Presumed Secondary to Zika Virus Infection in an Immunocompromised Adult

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):386-389. doi:10.1001/jamaophthalmol.2017.0098

This case report describes the imaging studies and clinical features of chorioretinal lesions in an immunocompromised patient with Zika virus infection.

Invited Commentary

Optical Coherence Tomography for the Noninvasive Detection of Elevated Intracranial Pressure: A New Role for the Ophthalmologist?

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):329-330. doi:10.1001/jamaophthalmol.2017.0021

Evaluation of Retinal Nerve Fiber Layer Thinning With Fourier-Domain Optical Coherence Tomography

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):337-338. doi:10.1001/jamaophthalmol.2017.0056

Genetics and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: What Have We Learned?

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):361-362. doi:10.1001/jamaophthalmol.2017.0136

Anti-VEGF Injections and Glaucoma Surgery

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):368-369. doi:10.1001/jamaophthalmol.2017.0148

Consensus on Optical Coherence Tomographic Angiography Nomenclature: Do We Need to Develop and Learn a New Language?

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):377-378. doi:10.1001/jamaophthalmol.2017.0149
JAMA Ophthalmology Clinical Challenge

White Vitreous Deposits After Subtenon Steroid Injection: More Than Meets the Eye

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):391-392. doi:10.1001/jamaophthalmol.2016.4192

A 58-year-old woman had 3 months of constant blurry vision in the left eye and a history of glaucoma and breast cancer. What would you do next?

Headaches and Blurry Vision

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):393-394. doi:10.1001/jamaophthalmol.2016.3831

A man presented with optic nerve hyperemia and multiple shallow serous retinal detachments. What would you do next?

Bilateral Retinal Hemorrhages in a Young Man

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):395-396. doi:10.1001/jamaophthalmol.2016.3867

A man in his 30s with no history of eye problems presented with flashes, progressive blurry vision in both eyes, easy bruising, and fatigue over a period of 6 days. Examination showed bilateral flame-shaped and intraretinal hemorrhages in both maculae and hard exudates in the left macula. What would you do next?

Recent Onset of Bilateral Ptosis

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):397-398. doi:10.1001/jamaophthalmol.2016.3827

A Hispanic man in his late 50s presented with gradual progression of bilateral blepharoptosis for 6 months, starting in the left eye and subsequently involving the right eye. The ptosis did not worsen throughout the day nor fluctuate. What would you do next?

Observation

Optic Nerve Infiltration and Vitreous Seeding by a Cerebral Glioblastoma

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):400-401. doi:10.1001/jamaophthalmol.2016.5835

This report is of a woman in her 40s with a recurrent cerebral malignant glioma in the left frontal lobe who presented with blurred vision in the right eye.

Comment & Response

Uncertainties in Big Data When Using Internet Surveillance Tools and Social Media for Determining Patterns in Disease Incidence

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):402. doi:10.1001/jamaophthalmol.2017.0138

Uncertainties in Big Data When Using Internet Surveillance Tools and Social Media for Determining Patterns in Disease Incidence—Reply

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):402-403. doi:10.1001/jamaophthalmol.2017.0140

Quantitative Fundus Autofluorescence

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):403. doi:10.1001/jamaophthalmol.2017.0104

Quantitative Fundus Autofluorescence—Reply

Abstract Full Text
JAMA Ophthalmol. 2017;135(4):403-404. doi:10.1001/jamaophthalmol.2017.0121
Correction

Corrections for Text

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):404. doi:10.1001/jamaophthalmol.2016.5651

Corrections for the Abstract, Author Affiliations, Text, and a Table

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):404. doi:10.1001/jamaophthalmol.2017.0439
Ophthalmic Images

Ultra Wide-Field Laser Scanning Imaging of an Unusually Bullous Retinoschisis: Retinoschisis vs Detachment

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):e165479. doi:10.1001/jamaophthalmol.2016.5479

This case report describes a man in his 40s with bullous retinoschisis extending into the macula.

Familial Exudative Vitreoretinopathy

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):e165487. doi:10.1001/jamaophthalmol.2016.5487

A 14-year-old boy noticed sudden vision loss in his right eye. Ophthalmoscopic examination revealed whitish vascular tufts in the temporal retinal periphery.

Peripheral Exudative Hemorrhagic Chorioretinopathy

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):e165491. doi:10.1001/jamaophthalmol.2016.5491

This case report describes a man in his 70s with peripheral exudative chorioretinopathy.

Serpiginous Choroiditis

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):e165495. doi:10.1001/jamaophthalmol.2016.5495

This case report describes a woman in her 40s who presented with bilateral, progressive, and blurry vision for 1 month.

JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2017;135(4):298. doi:10.1001/jamaophthalmol.2016.3728
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