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July 2019 - January 1929

Decade

Year

Issue

May 2017, Vol 135, No. 5, Pages 411-505

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
free access
JAMA Ophthalmol. 2017;135(5):411. doi:10.1001/jamaophthalmol.2016.3732
Viewpoint

MEKanisms of a Serous Complication

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):413-414. doi:10.1001/jamaophthalmol.2017.0275

This Viewpoint characterizes how an unexpected drug effect could potentially inform the mechanism of a poorly understood disease—specifically, how MEK inhibitor–associated retinopathy may inform central serous chorioretinopathy.

Original Investigation

Journal Club

Risk of Uveitis Among People With Psoriasis: A Nationwide Cohort Study

Abstract Full Text
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JAMA Ophthalmol. 2017;135(5):415-422. doi:10.1001/jamaophthalmol.2017.0569

This cohort study explores the association between uveitis and psoriasis without psoriatic arthritis.

Vascular Safety of Ranibizumab in Patients With Diabetic Macular Edema: A Pooled Analysis of Patient-Level Data From Randomized Clinical Trials

Abstract Full Text
free access
JAMA Ophthalmol. 2017;135(5):424-431. doi:10.1001/jamaophthalmol.2017.0455

This cohort study evaluates the safety of ranibizumab compared with sham and laser treatment in patients with diabetic macular edema.

Ophthalmic Screening Patterns Among Youths With Diabetes Enrolled in a Large US Managed Care Network

Abstract Full Text
free access has active quiz has audio
JAMA Ophthalmol. 2017;135(5):432-438. doi:10.1001/jamaophthalmol.2017.0089

This cohort study assesses the rate of obtaining ophthalmic examinations and factors associated with receipt of eye examinations for youths with diabetes.

Ophthalmic Manifestations of Congenital Zika Syndrome in Colombia and Venezuela

Abstract Full Text
free access has active quiz
JAMA Ophthalmol. 2017;135(5):440-445. doi:10.1001/jamaophthalmol.2017.0561

This case series reports the ocular manifestations of congenital Zika syndrome with microcephaly in infants in Colombia and Venezuela.

Association of a Haplotype in the NR3C2 Gene, Encoding the Mineralocorticoid Receptor, With Chronic Central Serous Chorioretinopathy

Abstract Full Text
free access
JAMA Ophthalmol. 2017;135(5):446-451. doi:10.1001/jamaophthalmol.2017.0245

This case-control, genetic association study assesses the association of functional variants and haplotypes in the glucocorticoid receptor (NR3C1) and mineralocorticoid receptor (NR3C2) genes with chronic central serous chorioretinopathy.

Economic Evaluation of a Home-Based Age-Related Macular Degeneration Monitoring System

Abstract Full Text
free access
JAMA Ophthalmol. 2017;135(5):452-459. doi:10.1001/jamaophthalmol.2017.0255

This economic analysis evaluates a home-based daily visual field monitoring system using simulation methods and applies the findings of the Home Monitoring of the Eye study to the US population at high risk for wet-form age-related macular degeneration.

Peripapillary Retinal Nerve Fiber Layer Vascular Microcirculation in Eyes With Glaucoma and Single-Hemifield Visual Field Loss

Abstract Full Text
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JAMA Ophthalmol. 2017;135(5):461-468. doi:10.1001/jamaophthalmol.2017.0261

This cross-sectional study investigates the microcirculation changes in the peripapillary retinal nerve fiber layer in eyes with glaucoma and single-hemifield visual field loss by using optical coherence tomography–based microangiography.

Ethnic Differences in the Association Between Age-Related Macular Degeneration and Vision-Specific Functioning

Abstract Full Text
free access
JAMA Ophthalmol. 2017;135(5):469-476. doi:10.1001/jamaophthalmol.2017.0266

This population-based, cross-sectional study examines the association between patient ethnicity and reduction in vision-specific functioning in Chinese, Malay, and Indian patients with age-related macular degeneration.

Brief Report

Acute Bilateral Photoreceptor Degeneration in an Infant After Vaccination Against Measles and Rubella

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):478-482. doi:10.1001/jamaophthalmol.2017.0380

This brief report report the findings in an infant boy who developed an acute loss of vision bilaterally after Haemophilus influenzae type b, Pneumococcal conjugate vaccination, and measles and rubella vaccination.

Microscope-Integrated Optical Coherence Tomography Angiography in the Operating Room in Young Children With Retinal Vascular Disease

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):483-486. doi:10.1001/jamaophthalmol.2017.0422

This case report investigates the feasibility of using microscope-integrated, swept-source optical coherence tomography in the operating room for 2 young children with retinal vascular disease.

Acute Zonal Cone Photoreceptor Outer Segment Loss

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):487-490. doi:10.1001/jamaophthalmol.2017.0451

This case report describes an adolescent boy with acute visual field loss to the cone photoreceptor outer segment despite normal results of a fundus examination.

Invited Commentary

The Draw(backs) of Big Data

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):422-423. doi:10.1001/jamaophthalmol.2017.0703

Diabetic Retinopathy Screening With Telemedicine: A Potential Strategy to Engage Our Youth

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):438-439. doi:10.1001/jamaophthalmol.2017.0150

Determining the Value of Home Monitoring of Patients With Age-Related Macular Degeneration

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):459-460. doi:10.1001/jamaophthalmol.2017.0133

Ethnic Differences in Self-reported Visual Function Among Patients With Age-Related Macular Degeneration: Implications for Care

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):476-477. doi:10.1001/jamaophthalmol.2017.0272
JAMA Ophthalmology Clinical Challenge

Acquired Diplopia in a Child

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2017;135(5):491-492. doi:10.1001/jamaophthalmol.2016.4417

A 6-year-old girl presented to the ophthalmology emergency service with 4 days of double vision associated with headache and fever. She had a history of upper respiratory tract infection with nasal congestion and discharge being treated with oral antibiotics. What would you do next?

Rapid Loss of Vision With the Onset of a White Ring Surrounding the Optic Nerve

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2017;135(5):493-494. doi:10.1001/jamaophthalmol.2016.4476

A white man in his 50s initially presented in the fall of 2015 with “macular changes” noticed by his referring optometrist. The patient was asymptomatic at the time. He had a history of hypertension and non-Hodgkin lymphoma, which was last treated in 2012 without evidence of recurrence. What would you do next?

Vision Loss With Pachymeningeal Enhancement on Magnetic Resonance Imaging

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2017;135(5):495-496. doi:10.1001/jamaophthalmol.2016.4542

A man in his 50s with a history of hypertension and sleep apnea presented with a 6-week history of progressive, bilateral vision loss while receiving treatment with oral steroids and amoxicillin-clavulanate from his primary care physician. What would you do next?

Retinal Vascular Changes in a Young Woman

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2017;135(5):497-498. doi:10.1001/jamaophthalmol.2016.4816

A woman in her teens presented with personality changes, headache, decreased vision bilaterally, concomitant hearing loss, and vertigo. Laboratory results showed an elevated white blood cell count, and fluorescein angiography showed multiple retinal arteriolar occlusions with variable leakage. What would you do next?

Observation

Treatment of Previously Refractory Ocular Surface Squamous Neoplasia With Topical Cidofovir

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):500-502. doi:10.1001/jamaophthalmol.2017.0365

This case report describes a man in his 70s who initially presented with multifocal lesions present for 18 months at the right superonasal and temporal limbal bulbar conjunctiva.

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Presenting With Unilateral Purtscherlike Retinopathy

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):502-503. doi:10.1001/jamaophthalmol.2017.0114

This case report describes a woman with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy who presented with near confluent peripapillary cotton wool spots, perifoveal areas of retinal whitening, venous tortuosity, and retinal hemorrhages in the left eye, suggestive of Purtscherlike retinopathy.

Regression of Subretinal Lymphoma After Diagnostic Vitrectomy

Abstract Full Text
JAMA Ophthalmol. 2017;135(5):503-505. doi:10.1001/jamaophthalmol.2017.0464

This case series describes 2 patients with subretinal lesions in the left eye who underwent pars plana vitrectomy for suspicion of primary vitreoretinal lymphoma.

Ophthalmic Images

Inadvertent Subconjunctival Injection of a Dexamethasone Implant

Abstract Full Text
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JAMA Ophthalmol. 2017;135(5):e170106. doi:10.1001/jamaophthalmol.2017.0106

This case report describes a man in his 60s with postsurgical cystoid macular edema who underwent a dexamethasone intravitreal implant.

Exclusion of Traumatic Anterior Capsule Laceration Using Anterior Segment Optical Coherence Tomography

Abstract Full Text
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JAMA Ophthalmol. 2017;135(5):e170124. doi:10.1001/jamaophthalmol.2017.0124

This case report describes a woman in her 60s who presented with a small corneal laceration and a formed anterior chamber with minimal wound leakage.

Numerous Smokestack and Inkblot Pattern Leaks in Central Serous Chorioretinopathy

Abstract Full Text
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JAMA Ophthalmol. 2017;135(5):e170128. doi:10.1001/jamaophthalmol.2017.0128

This case report describes a man in his 30s diagnosed as having central serous chorioretinopathy with both smokestack and inkblot leakage patterns.

Maxillary Sinus Wall Thickening in Silent Sinus Syndrome

Abstract Full Text
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JAMA Ophthalmol. 2017;135(5):e170637. doi:10.1001/jamaophthalmol.2017.0637

A 49-year-old woman presented with 6 months of progressive left superior sulcus hollowing unassociated with diplopia, trauma, sinus disease, or use of prostaglandin agonist drops.

JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2017;135(5):412. doi:10.1001/jamaophthalmol.2016.3733
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