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August 2019 - January 1929

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Issue

November 2018, Vol 136, No. 11, Pages 1213-1315

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
free access
JAMA Ophthalmol. 2018;136(11):1213. doi:10.1001/jamaophthalmol.2017.3753
Viewpoint

Correlation of Central Retinal Thickness and Visual Acuity in Diabetic Macular Edema

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1215-1216. doi:10.1001/jamaophthalmol.2018.3848

This Viewpoint posits that the correlation between central subfield thickness and visual acuity is low and suggests that anatomical and physiologic measurements should be used to assess visual acuity as well.

Original Investigation

Evaluation of Clinical Questions and Patient-Important Outcomes Associated With the Treatment of Age-Related Macular Degeneration

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1217-1225. doi:10.1001/jamaophthalmol.2018.3456

This study identifies clinical questions and patient-important outcomes prioritized using a modified Delphi process and associated with age-related macular degeneration, as well as their implications for future research and clinical care.

Differences in Tertiary Glaucoma Care in the Veterans Affairs Health Care System

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1227-1234. doi:10.1001/jamaophthalmol.2018.3463

This review of fiscal year 2016 data from the Veterans Health Administration Support Service Center database investigates whether the rate of tertiary glaucoma care differs among 4 different eye care delivery models within the Veterans Affairs health care system.

Immunotherapy With Programmed Cell Death 1 Inhibitors for 5 Patients With Conjunctival Melanoma

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1236-1241. doi:10.1001/jamaophthalmol.2018.3488

This cohort study describes the use of programmed cell death 1 inhibitors for the treatment of metastatic conjunctival melanoma in 5 adult patients.

Association of Preclinical Alzheimer Disease With Optical Coherence Tomographic Angiography Findings

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):1242-1248. doi:10.1001/jamaophthalmol.2018.3556

This case-control study assesses whether optical coherence tomographic (OCT) angiography can detect early retinal alterations in cognitively normal study participants with preclinical Alzheimer disease diagnosed by β-amyloid biomarker positivity.

Loss to Follow-up Among Patients With Neovascular Age-Related Macular Degeneration Who Received Intravitreal Anti–Vascular Endothelial Growth Factor Injections

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):1251-1259. doi:10.1001/jamaophthalmol.2018.3578

This cohort study investigates rates of risk factors associated with loss to follow-up after receipt of intravitreal injections of anti–vascular endothelial growth factor (anti-VEGF) injections among patients with neovascular age-related macular degeneration.

Association of Optical Coherence Tomography Angiography of Collaterals in Retinal Vein Occlusion With Major Venous Outflow Through the Deep Vascular Complex

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1262-1270. doi:10.1001/jamaophthalmol.2018.3586

This study of 23 eyes in 23 patients determines the location of collateral vessels in retinal vein occlusion with optical coherence tomography angiography imaging.

A Worldwide Price Comparison of Glaucoma Medications, Laser Trabeculoplasty, and Trabeculectomy Surgery

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1271-1279. doi:10.1001/jamaophthalmol.2018.3672

This cross-sectional study compares the prices of topical glaucoma medications, laser trabeculoplasty, and trabeculectomy with median annual household income for countries worldwide.

Spontaneous Resolution and Timing of Intervention in Congenital Nasolacrimal Duct Obstruction

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):1281-1286. doi:10.1001/jamaophthalmol.2018.3841

This population-based study investigates the optimal timing of intervention in congenital nasolacrimal duct obstruction by reviewing the age of spontaneous resolution in a cohort of affected infants.

Brief Report

Use of En Face Swept-Source Optical Coherence Tomography Angiography in Identifying Choroidal Flow Voids in 3 Patients With Birdshot Chorioretinopathy

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1288-1292. doi:10.1001/jamaophthalmol.2018.3474

This study of 3 patients with birdshot chorioretinopathy tests the feasibility of swept-source optical coherence tomography angiography in the detection of choroidal lesions.

Invited Commentary

Prioritizing Questions and Outcomes for Guidelines on Age-Related Macular Degeneration: Moving Beyond the Clinical Encounter

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1225-1226. doi:10.1001/jamaophthalmol.2018.3455

Collaboration Is Needed to Improve the Quality of Eye Care and Eliminate Inequities

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1234-1235. doi:10.1001/jamaophthalmol.2018.3768

Viewing Retinal Vasculature in Alzheimer Disease

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1249-1250. doi:10.1001/jamaophthalmol.2018.3569

Anti-VEGF Neovascular Age-Related Macular Degeneration Treatment Adherence Requires Attention and Action

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1260-1261. doi:10.1001/jamaophthalmol.2018.3595

Affordability of Glaucoma Treatment Around the Globe: An Initial Step Toward Improving Universal Access to Glaucoma Treatment

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1279-1280. doi:10.1001/jamaophthalmol.2018.3670

Timing of Simple Probing for Congenital Nasolacrimal Duct Obstruction: Not So Simple

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1286-1287. doi:10.1001/jamaophthalmol.2018.3855

Survival Analysis and the Immortal Time Bias

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1314-1315. doi:10.1001/jamaophthalmol.2018.3499
JAMA Ophthalmology Clinical Challenge

Unilateral Eyelid Swelling With Submandibular Lymph Node Enlargement

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):1293-1294. doi:10.1001/jamaophthalmol.2018.0801

A woman presents with a nasal polyp and soft tissue mass in the right lacrimal gland region accompanied by decreased visual acuity and fever. What would you do next?

Hidden Globe in an Infant

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2018;136(11):1295-1296. doi:10.1001/jamaophthalmol.2018.0932

A healthy 7-month-old boy presented for oculoplastic evaluation with an enlarging right periorbital mass, asymmetry between the eyes since birth, and progressive right lower eyelid fullness. What would you do next?

A Child With Unilateral Conjunctivitis and Elevated Inflammatory Markers

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2018;136(11):1297-1298. doi:10.1001/jamaophthalmol.2018.0936

A previously healthy adolescent boy presented with fever, headache, and unilateral red eye with periorbital edema; after failure to improve, the patient developed submandibular lymphadenopathy, ipsilateral granulomatous conjunctivitis, and elevated inflammatory markers. What would you do next?

Sudden Unilateral Decrease in Vision in a Healthy Middle-aged Man

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):1299-1300. doi:10.1001/jamaophthalmol.2018.1375

A previously healthy man in his 50s presented with a 1-day history of sudden painful decreased vision in the right eye, with conjunctival injection, nongranulomatous keratic precipitates, optic nerve swelling, intraretinal hemorrhages, and perivascular sheathing. What would you do next?

Sudden-Onset Unilateral Macular Hemorrhage in a Middle-aged Man

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2018;136(11):1301-1302. doi:10.1001/jamaophthalmol.2018.1095

A man in his 50s presents with sudden deceased visual acuity and macular hemorrhage in 1 eye. What would you do next?

Macular Vitelliform-Like Lesion in an Eye With Chronic Retinal Detachment

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2018;136(11):1303-1304. doi:10.1001/jamaophthalmol.2018.1379

A 41-year-old woman with a history of ocular hypertension who had previously undergone pneumatic retinopexy for macula-on retinal detachment with a superotemporal tear and 1 month later underwent a vitrectomy with gas injection for macula-on inferonasal detachment presented with yellowish subfoveal precipitates in her left eye. What would you do next?

Research Letter

Utility of Deep Learning Methods for Referability Classification of Age-Related Macular Degeneration

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1305-1307. doi:10.1001/jamaophthalmol.2018.3799

This study uses fundus images from a national data set to assess 2 deep learning methods for referability classification of age-related macular degeneration.

Observation

Combined Central Retinal Artery and Vein Occlusion From a Presumed Arteriovenous Fistula After Retrobulbar Anesthesia

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1307-1309. doi:10.1001/jamaophthalmol.2018.3224

This case report describes a man in his 60s with combined central retinal artery and vein occlusion from a presumed central retinal arteriovenous fistula secondary to retrobulbar anesthesia.

Comment & Response

Measuring Optic Nerve Sheath Diameter as a Proxy for Intracranial Pressure

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1309. doi:10.1001/jamaophthalmol.2018.3426

Measuring Optic Nerve Sheath Diameter as a Proxy for Intracranial Pressure

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1309-1310. doi:10.1001/jamaophthalmol.2018.3429

Measuring Optic Nerve Sheath Diameter as a Proxy for Intracranial Pressure

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1310. doi:10.1001/jamaophthalmol.2018.3432

Measuring Optic Nerve Sheath Diameter as a Proxy for Intracranial Pressure

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1310-1311. doi:10.1001/jamaophthalmol.2018.3435

Measuring Optic Nerve Sheath Diameter as a Proxy for Intracranial Pressure—Reply

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1311-1312. doi:10.1001/jamaophthalmol.2018.3438

Incidence and Causes of Overdiagnosis of Optic Neuritis: Physician Insecurity

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1312. doi:10.1001/jamaophthalmol.2018.3482

Incidence and Causes of Overdiagnosis of Optic Neuritis: Physician Insecurity—Reply

Abstract Full Text
JAMA Ophthalmol. 2018;136(11):1312-1313. doi:10.1001/jamaophthalmol.2018.3485

Notice of Retraction and Replacement. Tseng et al. Association of cataract surgery with mortality in older women: findings from the Women’s Health Initiative. JAMA Ophthalmol. 2018;136(1):3-10

Abstract Full Text
free access
JAMA Ophthalmol. 2018;136(11):1313-1314. doi:10.1001/jamaophthalmol.2018.3347

Notice of Retraction and Replacement. Tseng et al. Association of cataract surgery with mortality in older women: findings from the Women’s Health Initiative. JAMA Ophthalmol. 2018;136(1):3-10

Correction

Incorrect Orientation of Figure 2

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):1315. doi:10.1001/jamaophthalmol.2018.5010
Ophthalmic Images

Anterior Segment Optical Coherence Tomography Angiography in a Patient With Persistent Pupillary Membrane

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):e182932. doi:10.1001/jamaophthalmol.2018.2932

This case report describes a patient with bilateral cataracts and persistent pupillary membrane.

Penetrating Injury With Foreign Body in the Angle of the Left Eye

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):e183064. doi:10.1001/jamaophthalmol.2018.3064

This case report describes a patient in his 30s with a metallic foreign body in the inferior angle of the left eye.

Long-term Minocycline Therapy With Scleral Pigmentation Simulating Melanocytosis

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):e183088. doi:10.1001/jamaophthalmol.2018.3088

This case report describes a white man in his 70s with unrelated cutaneous mycosis fungoides and secondary follicular mucinosis who developed melanocytosis after long-term treatment with minocycline.

Retinal Angiography Findings in Male Infant With Incontinentia Pigmenti and Sickle Cell Trait

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):e183140. doi:10.1001/jamaophthalmol.2018.3140

This case report describes fluorescein angiography results of a neonate with a combination diagnosis of incontinentia pigmenti and sickle cell trait.

JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2018;136(11):1214. doi:10.1001/jamaophthalmol.2017.3754
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