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May 2019 - January 1929

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Issue

April 2018, Vol 136, No. 4, Pages 311-454

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2018;136(4):311. doi:10.1001/jamaophthalmol.2017.3718
Viewpoint

A Collaborative Community Model for Including Minorities in Genetic Research

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):313-314. doi:10.1001/jamaophthalmol.2018.0225

This Viewpoint assesses the benefits of collaborative community outreach to enroll minorities in genetic research.

Original Investigation

Association of Changes in Macular Perfusion With Ranibizumab Treatment for Diabetic Macular Edema: A Subanalysis of the RESTORE (Extension) Study

Abstract Full Text
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JAMA Ophthalmol. 2018;136(4):315-321. doi:10.1001/jamaophthalmol.2017.6135

This post hoc analysis of data from a randomized clinical trial evaluates the association of repeated ranibizumab injections on macular perfusion in patients with diabetic macular edema as compared with laser monotherapy or ranibizumab and laser combination therapy.

Differentiating Acute and Subacute Vertical Strabismus Using Different Head Positions During the Upright-Supine Test

Abstract Full Text
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JAMA Ophthalmol. 2018;136(4):322-328. doi:10.1001/jamaophthalmol.2017.6796

This study determines the sensitivity and specificity of vertical misalignment changes using different head positions during the upright-supine test for the diagnosis of acute/subacute skew vs fourth nerve palsy.

Detection of Glaucoma Progression in Individuals of African Descent Compared With Those of European Descent

Abstract Full Text
free access has active quiz
JAMA Ophthalmol. 2018;136(4):329-335. doi:10.1001/jamaophthalmol.2017.6836

This cohort study investigates racial differences in longitudinal visual field variability and their impact on time to detect visual field progression.

Comparison of Monthly vs Treat-and-Extend Regimens for Individuals With Macular Edema Who Respond Well to Anti–Vascular Endothelial Growth Factor Medications: Secondary Outcomes From the SCORE2 Randomized Clinical Trial

Abstract Full Text
free access has audio
JAMA Ophthalmol. 2018;136(4):337-345. doi:10.1001/jamaophthalmol.2017.6843

This secondary analysis of a randomized clinical trial compares visual acuity letter score and central subfield thickness outcomes in participants who received either monthly injections or a treat-and-extend regimen of aflibercept or bevacizumab.

Factors Associated With Health-Related Quality of Life in Medically and Surgically Treated Patients With Glaucoma

Abstract Full Text
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JAMA Ophthalmol. 2018;136(4):348-355. doi:10.1001/jamaophthalmol.2018.0012

This study determines factors associated with reduced health-related quality of life in medically and surgically treated patients with glaucoma.

Sociodemographic, Medical, and Psychosocial Factors Associated With Supportive Care Needs in Adults Diagnosed With Uveal Melanoma

Abstract Full Text
free access has active quiz
JAMA Ophthalmol. 2018;136(4):356-363. doi:10.1001/jamaophthalmol.2018.0019

This study examines the needs of patients newly diagnosed with uveal melanoma and the sociodemographic, medical, and psychosocial factors that predict unmet need severity.

Comparison of Subjective Assessment and Precise Quantitative Assessment of Lesion Distribution in Diabetic Retinopathy

Abstract Full Text
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JAMA Ophthalmol. 2018;136(4):365-371. doi:10.1001/jamaophthalmol.2018.0070

This multisite cross-sectional study compares subjective and precise quantitative classification of diabetic retinopathy lesion distribution from nonmydriadic ultrawidefield pseudocolor images.

Congenital Retinal Macrovessel and the Association of Retinal Venous Malformations With Venous Malformations of the Brain

Abstract Full Text
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JAMA Ophthalmol. 2018;136(4):372-379. doi:10.1001/jamaophthalmol.2018.0150

This cross-sectional study studies the multimodal imaging findings of a series of eyes with congenital retinal macrovessel and describes the systemic associations.

Aqueous Humor Cytokine Levels and Anatomic Response to Intravitreal Ranibizumab in Diabetic Macular Edema

Abstract Full Text
free access
JAMA Ophthalmol. 2018;136(4):382-388. doi:10.1001/jamaophthalmol.2018.0179

This cohort study investigates aqueous humor cytokine level changes in response to intravitreal ranibizumab therapy for the management of diabetic macular edema.

Presentation of TRPM1-Associated Congenital Stationary Night Blindness in Children

Abstract Full Text
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JAMA Ophthalmol. 2018;136(4):389-398. doi:10.1001/jamaophthalmol.2018.0185

This study describes the pediatric presentation and childhood course of TRPM1-associated complete congenital stationary night blindness.

Rehabilitation Referral for Patients With Irreversible Vision Impairment Seen in a Public Safety-Net Eye Clinic

Abstract Full Text
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JAMA Ophthalmol. 2018;136(4):400-408. doi:10.1001/jamaophthalmol.2018.0241

This cross-sectional study investigates the rate of referral of adults with irreversible vision impairment to low-vision rehabilitation services at an urban, publicly funded, comprehensive eye clinic.

Validation of the Colorado Retinopathy of Prematurity Screening Model

Abstract Full Text
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JAMA Ophthalmol. 2018;136(4):409-416. doi:10.1001/jamaophthalmol.2018.0376

This validation study evaluates the sensitivity of the Colorado Retinopathy of Prematurity model in a large, diverse cohort of premature infants.

Brief Report

Prevalence of Myelin Oligodendrocyte Glycoprotein and Aquaporin-4–IgG in Patients in the Optic Neuritis Treatment Trial

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):419-422. doi:10.1001/jamaophthalmol.2017.6757

This case report examines the aquaporin-4–IgG and myelin oligodendrocyte glycoprotein–IgG serostatus of patients within the Optic Neuritis Treatment Trial and describes the clinical features of seropositive patients.

Association of Social Support Network Size With Receipt of Cataract Surgery in Older Adults

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):423-427. doi:10.1001/jamaophthalmol.2018.0244

This cohort study determines if older adults with smaller social support networks are less likely to receive cataract surgery.

Utilization of Ophthalmologist Consultation for Emergency Care at a University Hospital

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):428-431. doi:10.1001/jamaophthalmol.2018.0250

This study uses emergency department electronic medical records and billing data to assess odds of receiving an ophthalmology consultation among patients presenting with eye problems.

Invited Commentary

Visual Field Progression Is More Complicated Than Meets the Eye

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):335-336. doi:10.1001/jamaophthalmol.2017.6852

The SCORE2 Comparison of Treat-and-Extend vs Monthly Anti–Vascular Endothelial Growth Factor Dosing: Short-term Similarities and Longer-term Questions

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):346-347. doi:10.1001/jamaophthalmol.2017.6855

Reappraising the Psychosocial Needs of Patients With Uveal Melanoma

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):363-364. doi:10.1001/jamaophthalmol.2017.6576

Association of Retinal Macrovessels With Venous Malformations of the Brain

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):380-381. doi:10.1001/jamaophthalmol.2018.0149

Revisiting Congenital Stationary Night Blindness in the Molecular Era

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):398-399. doi:10.1001/jamaophthalmol.2018.0193

Weighing in on New Screening Models for Retinopathy of Prematurity

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):417-418. doi:10.1001/jamaophthalmol.2018.0359
New Instrument

Stereoscopic Microsurgical Videography of Phacoemulsification Surgery

Abstract Full Text
has multimedia
JAMA Ophthalmol. 2018;136(4):432-433. doi:10.1001/jamaophthalmol.2018.0089

This new instrument review describes the use of a portable 3-dimensional microsurgical recording system, combined with existing virtual reality technology, to record phacoemulsification surgery and discusses the potential use of this technology in surgical training.

JAMA Ophthalmology Clinical Challenge

A Case of Progressive Dimming Vision

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2018;136(4):434-435. doi:10.1001/jamaophthalmol.2017.4162

A man in his early 70s with 2 months of progressive dimming of his vision presented to his primary care physician reporting unintentional weight loss, fevers, and subacute visual decline. What would you do next?

Persistent Angiographic Abnormalities After Intravitreal Anti–Vascular Endothelial Growth Factor Therapy for Retinopathy of Prematurity

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2018;136(4):436-437. doi:10.1001/jamaophthalmol.2017.4172

A female patient with a history of premature birth and zone I, stage 3 retinopathy of prematurity with plus disease treated with a single injection of 0.625 mg of intravitreal bevacizumab in each eye presents for routine examination at 2 years of age. What would you do next?

Bulbar Conjunctival Nodule in a Patient With Rheumatoid Arthritis

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2018;136(4):438-439. doi:10.1001/jamaophthalmol.2017.4271

A 25-year-old man with a history of rheumatoid arthritis currently taking oral methotrexate 25 mg per week presented with a lesion of the left bulbar conjunctiva of about 1 month’s duration. The lesion measured 6.5 × 2.5 mm and was firm, nonvascular, slightly mobile, and located on the superotemporal portion of the bulbar conjunctiva. What would you do next?

Recurrent Monocular Vision Loss and an Ocular Mass

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2018;136(4):440-441. doi:10.1001/jamaophthalmol.2017.4285

A woman with a right orbital mass experiences transient, monocular vision loss after use of an electronic tablet in dim light. What would you do?

Congenital Restrictive Strabismus

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2018;136(4):442-443. doi:10.1001/jamaophthalmol.2017.4345

A 1-year-old boy with a history of restricted movements of the left eye had massive enlargement of the superior, inferior, and medial rectus muscles. What is your diagnosis?

Chronic Inflammation After YAG Capsulotomy

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2018;136(4):444-445. doi:10.1001/jamaophthalmol.2017.4372

A 65-year-old man referred for evaluation of uveitis in the left eye presented with a red, painful left eye and visual acuity that had declined to counting fingers after undergoing YAG capsulotomy. What would you do next?

Research Letter

Efficacy of Multicolor Imaging in Patients With Asteroid Hyalosis: Seeing the Unseen

Abstract Full Text
free access
JAMA Ophthalmol. 2018;136(4):446-447. doi:10.1001/jamaophthalmol.2018.0026

This case report assesses 2 patients with asteroid hyalosis with novel multicolor imaging technology; results highlight the value of this approach relative to color fundus photography and spectral-domain optical coherence tomography.

Comment & Response

Methodological and Efficacy Issues in a Randomized Clinical Trial Investigating Vitreous Floater Treatment

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):447-448. doi:10.1001/jamaophthalmol.2018.0207

Methodological and Efficacy Issues in a Randomized Clinical Trial Investigating Vitreous Floater Treatment

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):448. doi:10.1001/jamaophthalmol.2018.0212

Methodological and Efficacy Issues in a Randomized Clinical Trial Investigating Vitreous Floater Treatment

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):449. doi:10.1001/jamaophthalmol.2018.0215

Methodological and Efficacy Issues in a Randomized Clinical Trial Investigating Vitreous Floater Treatment—Reply

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):449-450. doi:10.1001/jamaophthalmol.2018.0218

Potential Confounders in an Investigation of the Vision-Related Functional Burden of Diabetic Retinopathy—Reply

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):450-451. doi:10.1001/jamaophthalmol.2017.6573

Potential Confounders in an Investigation of the Vision-Related Functional Burden of Diabetic Retinopathy

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):450. doi:10.1001/jamaophthalmol.2017.6703

Why Space Flight–Associated Neuro-ocular Syndrome May Differ From Idiopathic Intracranial Hypertension

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):451-452. doi:10.1001/jamaophthalmol.2018.0316

Why Space Flight-Associated Neuro-ocular Syndrome May Differ From Idiopathic Intracranial Hypertension—Reply

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):452. doi:10.1001/jamaophthalmol.2018.0319

Questioning Macular Pigment Measurement Methods and Genetic Risk of Age-Related Macular Degeneration

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):453. doi:10.1001/jamaophthalmol.2018.0326

Questioning Macular Pigment Measurement Methods and Genetic Risk of Age-Related Macular Degeneration—Reply

Abstract Full Text
JAMA Ophthalmol. 2018;136(4):453-454. doi:10.1001/jamaophthalmol.2018.0329
Correction

Error in Funding/Support

Abstract Full Text
free access
JAMA Ophthalmol. 2018;136(4):454. doi:10.1001/jamaophthalmol.2018.0031
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2018;136(4):312. doi:10.1001/jamaophthalmol.2017.3719
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