This randomized clinical trial evaluates the potential efficacy and assesses the safety of orally administered valproic acid in the treatment of autosomal dominant retinitis pigmentosa.
This national UK transplant registry study examines the corneal transplant replacement survival rates for the 3 main indications and types of regraft surgery.
This cross-sectional study compares the use of optical coherence tomography angiography with optical coherence tomography in the diagnosis and evaluation of inner macular thickness and inner macular vessel density in patients with glaucoma.
This multicenter genome-wide association study identifies genetic factors associated with variability in the response to anti–vascular endothelial growth factor therapy for patients with neovascular age-related macular degeneration.
This study investigates the role of guttae in the pathogenesis of Fuchs endothelial corneal dystrophy by examining their association with corneal endothelial cell function.
This study characterizes pediatric acute ocular injury in the United States using data from a stratified, national sample of emergency department visits.
This prospective observational study investigates the incidence of fellow eye involvement in patients with unilateral typical age-related macular degeneration or polypoidal choroidal vasculopathy.
This longitudinal study investigates the association of atopic dermatitis with subsequent cataract development and cataract surgery in a Korean pediatric population.
This cohort study analyzes the association of best-corrected visual acuity loss with foveal phenotype and genotype in patients with Stargardt disease.
This cross-sectional study quantifies capillary nonperfusion in 3 vascular plexuses in the macula of eyes of patients with diabetes and various retinopathy severity using projection-resolved optical coherence tomography angiography (OCTA).
This cross-sectional study assesses an academic-related fine motor outcome—multiple-choice answer form completion time—in children with amblyopia and strabismus.
A 63-year-old man with type 2 diabetes for 10 years was seen with decreased vision in both eyes. He was diagnosed as having nonproliferative diabetic retinopathy with macular edema in both eyes and received 3 intravitreal bevacizumab injections at 4 weekly intervals and 2 intravitreal triamcinalone acetonide injections in both eyes, with minimal resolution of edema. What would you do next?
A woman in her early 50s with a history of cystic fibrosis, cytomegalovirus viremia, and chronic kidney disease who has been treated with cidofovir presents with headaches, bilateral photophobia, and blurry vision. What would you do next?
A young pregnant woman with proliferative diabetic retinopathy presents with subacute bilateral vision loss. Examination reveals mild optic nerve head edema and macular edema. What would you do next?
A 14-year-old girl was seen with progressive vision loss in both eyes. Optic nerve atrophy was noted, with no optociliary collaterals. Imaging of the retinal nerve fiber layer showed thinning in both eyes. What would you do next?
A man in his 60s presents to your neuro-ophthalmology clinic with worsening ptosis after ptosis repair surgery. The affected eye demonstrates total ophthalmoplegia and enophthalmos. What would you do next?
A woman presents with bilateral acute-angle closure and retinal detachments. What would you do?
This case report describes a patient with chronic retinal detachment with large macular and peripheral retinal pseudocysts and discusses the histologic features of such retinal macro-pseudocysts and their implications.
This case report describes physical capillary disruption during inner retinal schisis enlargement in a woman in her 30s.
A woman in her mid-50s with squamous cell carcinoma in the right maxillary sinus developed widespread punctate pigment abnormalities consistent with radiation-related retinal pigment epitheliopathy after external beam radiation therapy.
This case study describes a 9-year-old child with a radial spoke of capillary dropout emanating from the optic disc pit of the left eye.
This case study describes a 50-year-old man with intraocular bone formation 4 decades after ocular trauma.
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