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August 2021 - January 1929

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November 2019, Vol 137, No. 11, Pages 1221-1334

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1221. doi:10.1001/jamaophthalmol.2018.4798
Original Investigation

Sex Disparities in Ophthalmic Research: A Descriptive Bibliometric Study on Scientific Authorships

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1223-1231. doi:10.1001/jamaophthalmol.2019.3095

This bibliometric analysis explores sex distributions in ophthalmic research by evaluating the representation of female authorships.

Current Prevalence of Myopia and Association of Myopia With Environmental Factors Among Schoolchildren in Japan

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1233-1239. doi:10.1001/jamaophthalmol.2019.3103

This cross-sectional study examines the current prevalence rate of myopia and the association between environmental factors and myopia in Japanese schoolchildren.

Assessment of the Quality, Content, and Readability of Freely Available Online Information for Patients Regarding Diabetic Retinopathy

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1240-1245. doi:10.1001/jamaophthalmol.2019.3116

This cross-sectional study assesses the quality, content, and readability of diabetic retinopathy information found online.

Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients With Choroideremia: A Randomized Clinical Trial

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1247-1254. doi:10.1001/jamaophthalmol.2019.3278

This randomized clinical trial evaluates the efficacy of administration of an adeno-associated virus vector designed to deliver a functional version of the CHM gene in patients with choroideremia.

Clinical Effectiveness of Intravitreal Therapy With Ranibizumab vs Aflibercept vs Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion: A Randomized Clinical Trial

Abstract Full Text
open access has active quiz
JAMA Ophthalmol. 2019;137(11):1256-1264. doi:10.1001/jamaophthalmol.2019.3305

This randomized clinical trial compares the clinical effectiveness of intravitreal therapy with ranibizumab vs aflibercept vs bevacizumab for the management of macular edema secondary to central retinal vein occlusion.

Effect of Eye Masks on Neonatal Stress Following Dilated Retinal Examination: The MASK-ROP Randomized Clinical Trial

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1265-1272. doi:10.1001/jamaophthalmol.2019.3379

This randomized clinical trial determines the effect of a phototherapy mask worn during mydriasis on infant stress in the 12 hours after retinopathy of prematurity screening.

Phenotypic Spectrum of Pentosan Polysulfate Sodium–Associated Maculopathy: A Multicenter Study

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1275-1282. doi:10.1001/jamaophthalmol.2019.3392

This case series study describes the exposure characteristics and clinical manifestations of pentosan polysulfate sodium–associated maculopathy.

Association of Opioids With Incisional Ocular Surgery

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1283-1291. doi:10.1001/jamaophthalmol.2019.3694

This cohort study of claims from a national US insurer examines trends in and factors associated with rates of filled opioid prescriptions after incisional ocular surgeries.

Brief Report

Outcome Specification in a Sample of Publicly Funded Eye and Vision Trials Registered on ClinicalTrials.gov

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1292-1294. doi:10.1001/jamaophthalmol.2019.3289

This study identifies and characterizes outcomes specified in ClinicalTrials.gov records for publicly funded clinical trials for 3 high-burden, high-prevalence eye conditions.

Clinical Characterization of Retinitis Pigmentosa Associated With Variants in SNRNP200

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1295-1300. doi:10.1001/jamaophthalmol.2019.3298

This study describes the retinal phenotype secondary to variants in the SNRNP200 gene among patients with retinitis pigmentosa.

Association of Weight Gain Acceleration With Risk of Retinopathy of Prematurity

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1301-1305. doi:10.1001/jamaophthalmol.2019.3447

This secondary analysis of data from the Postnatal Growth and Retinopathy of Prematurity study evaluates whether faster infant weight gain acceleration during a later postnatal period is associated with a higher risk of severe retinopathy of prematurity.

Association Between Cilioretinal Arteries and Advanced Age-Related Macular Degeneration: Secondary Analysis of the Comparison of Age-Related Macular Degeneration Treatment Trials (CATT)

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1306-1311. doi:10.1001/jamaophthalmol.2019.3509

This cohort study and secondary analysis of the Comparison of Age-Related Macular Degeneration Treatments Trials assesses the association between the presence of a cilioretinal artery and incidence of age-related macular degeneration (AMD) among patients without advanced AMD in the fellow eye.

Prevalence of Cerebrotendinous Xanthomatosis Among Patients Diagnosed With Acquired Juvenile-Onset Idiopathic Bilateral Cataracts

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1312-1316. doi:10.1001/jamaophthalmol.2019.3639

This multicenter study evaluates the prevalence of cerebrotendinous xanthomatosis in a patient population diagnosed as having early-onset idiopathic bilateral cataracts.

Evaluating Whether Sight Is the Most Valued Sense

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1317-1320. doi:10.1001/jamaophthalmol.2019.3537

This cross-sectional study evaluates the ranking of sight among 8 senses among UK adults.

Invited Commentary

The Glass Ceiling in Ophthalmology—Next Comes How to Change This

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1231-1232. doi:10.1001/jamaophthalmol.2019.3113

Online Information for Diabetic Retinopathy—Often a Missed Opportunity for Patient Education

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1246. doi:10.1001/jamaophthalmol.2019.3146

Gene Therapy for Choroideremia—Progress and Remaining Questions

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1254-1255. doi:10.1001/jamaophthalmol.2019.3295

Caring for Infants Undergoing Screening for Retinopathy of Prematurity

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1273-1274. doi:10.1001/jamaophthalmol.2019.3377
JAMA Ophthalmology Clinical Challenge

A Woman With Bilateral Retinal Detachments

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1321-1322. doi:10.1001/jamaophthalmol.2019.3086

A 33-year-old black woman presents with bilateral retinal detachments after a flulike illness. Fundus and B-scan ultrasonographic examinations reveal several abnormalities. What would you do next?

Bilateral Limbus-Sparing Conjunctivitis in a Boy With Rash and Pneumonia

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1323-1324. doi:10.1001/jamaophthalmol.2019.3137

An adolescent boy presented with bilateral eye redness, an erythematous chest rash, lip blistering, and worsening sore throat for 2 days while receiving ciprofloxacin and trimethoprim-sulfamethoxazole for community-acquired pneumonia. Bedside ophthalmic examination revealed bilateral limbus-sparing conjunctival hyperemia that blanched minimally with phenylephrine, bilateral nasal and temporal conjunctival epithelial ulcerations, and inferior forniceal pseudomembranes. What would you do next?

Middle-aged Man With Foveal Photoreceptor Loss

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1325-1326. doi:10.1001/jamaophthalmol.2019.3643

A 38-year-old man with an unremarkable medical history presented with bilateral macular lesions. What would you do next?

An 18-Month-Old With a White Optic Nerve Head Mass

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1327-1328. doi:10.1001/jamaophthalmol.2019.3798

An 18-month-old girl presents with an intraocular mass near the optic nerve. What would you do next?

Ophthalmic Images

Lipemia Retinalis in a Woman With Hypertriglyceridemia

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):e186224. doi:10.1001/jamaophthalmol.2018.6224

This case report describes a 35-year-old woman with type 2 diabetes mellitus and hypertriglyceridemia who presented for evaluation of double vision and was found to have lipemia retinalis.

Optical Coherence Tomography Monitoring in a Patient With Retinoblastoma

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):e186243. doi:10.1001/jamaophthalmol.2018.6243

This case report describes a 17-month-old girl with group B retinoblastoma treated with cycles of chemotherapy.

Optical Coherence Tomography Angiography in a Patient With Diabetes and Preretinal Neovascularization

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):e190122. doi:10.1001/jamaophthalmol.2019.0122

This case report describes a 39-year-old patient with type 2 diabetes whose bilateral proliferative diabetic retinopathy was visualized with optical coherence tomography angiography rather than fluorescein angiography.

Optic Nerve Hypoplasia in the Eye and Beyond

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):e190126. doi:10.1001/jamaophthalmol.2019.0126

This case reports described a child with a deviation of the left eye and a large porencephalic cyst communicating with the left lateral ventricles.

Comment & Response

Emphasizing Optimal Diabetes Management for All Races/Ethnicities, but Not Race/Ethnicity–Specific Cut Points for Hemoglobin A1c

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1329. doi:10.1001/jamaophthalmol.2019.3230

Emphasizing Optimal Diabetes Management for All Races/Ethnicities, but Not Race/Ethnicity–Specific Cut Points for Hemoglobin A1c

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1329-1330. doi:10.1001/jamaophthalmol.2019.3233

Lamina Cribrosa Pore Diameter and Spaceflight-Associated Neuro-ocular Syndrome

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1330-1331. doi:10.1001/jamaophthalmol.2019.3319

Lamina Cribrosa Pore Diameter and Spaceflight-Associated Neuro-ocular Syndrome—Reply

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1331. doi:10.1001/jamaophthalmol.2019.3322

Leonardo da Vinci Probably Did Not Have Strabismus

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1331-1332. doi:10.1001/jamaophthalmol.2019.2214

Leonardo da Vinci Probably Did Not Have Strabismus—Reply

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1332-1333. doi:10.1001/jamaophthalmol.2019.2218

Nonperfused Inner Retina May Be Anoxic, Hypoxic, or Normoxic

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1333. doi:10.1001/jamaophthalmol.2019.3588

Calcium, Diet, Imaging, and Age-Related Macular Degeneration

Abstract Full Text
JAMA Ophthalmol. 2019;137(11):1333-1334. doi:10.1001/jamaophthalmol.2019.2725
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2019;137(11):1222. doi:10.1001/jamaophthalmol.2018.4799
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