This Viewpoint describes US Food and Drug Administration programs designed with the aim of enhancing and expediting the regulatory process to bring ophthalmic devices to patients more rapidly and efficiently.
This cross-sectional study compares the sensitivity and specificity of automated classification of glaucomatous optic neuropathy on retinal fundus images by a deep-learning system with classification by human experts, using Chinese, multiethnic, and website-based data sets.
This study evaluates the epidemiologic patterns of firearm-related ocular injuries among children and adolescents in the United States, using multiyear demographic, hospitalization, and clinical data reported in the National Trauma Data Bank.
This randomized clinical trial assesses the effects of dark chocolate flavanols on subjective visual function and retinal perfusion objectively quantified on optical coherence tomography angiography.
This case series describes an in vitro mutagenesis assay performed to confirm pathogenicity in 4 children or adolescents with Leber congenital amaurosis.
This secondary analysis of a randomized clinical trial investigates outcomes 1 year after cessation of the SCORE2 treatment schedule (24 months after randomization) in patients treated with anti–vascular endothelial growth factor (anti-VEGF) therapy for macular edema due to central retinal or hemiretinal vein occlusion.
This cross-sectional study of systematic reviews assesses the reliability of systematic reviews on interventions for 7 retina and vitreous conditions.
This cross-sectional study assesses the association between choroidal thickness and secondhand smoking exposure in children.
This cohort study uses data from patients with ocular hypertension to assess how well Kalman filtering, a machine learning approach used in aviation, can forecast disease trajectory up to 5 years into the future.
This preplanned secondary analysis of a randomized clinical trial assesses the 5- and 10-year incremental cost-effectiveness ratios of ranibizumab therapy compared with panretinal photocoagulation for treating patients diagnosed with proliferative diabetic retinopathy.
This clinical case series evaluates the pathogenesis of unilateral multifocal uveal melanoma in 4 affected individuals.
This case report describes the occurrence of corneal inlay damage following treatment to the eyelids and face with an Nd:YAG laser.
This case series examines the use of integrative exome and transcriptome analysis of genes and mutations in 8 patients with conjunctival melanoma.
This article discusses a study published in JAMA of the effect of methrotrexate vs mycophenolate as the single immunosuppressive agent on the treatment of noninfectious intermediate, posterior, and panuveitides.
A middle-aged woman presents with unilateral blurry vision, and imaging reveals a choroidal mass. What would you do next?
A Chinese woman had a painless, gradually declined vision for 2 years without redness. What would you do next?
A man in his 80s with pseudophakia presented for routine follow-up of an elevated choroidal nevus in his right eye. His slitlamp and fundus examinations were unremarkable aside from the choroidal nevus, and a new retro-orbital hypoechoic cavity causing right globe deformation was noted on B-scan ultrasonography. What would you do next?
This case series evaluates the classical complement pathway in eyes with cancer-associated retinopathy.
This case report describes a woman with central retinal artery occlusion following triamcinolone injection of the lacrimal gland.
This case report details a case of epithelial invasion after Descemet membrane endothelial keratoplasty in an elderly woman.
This case report describes rubeosis iridis in a woman who was found to also have proliferative diabetic retinopathy in both eyes.
This case report describes the aftermath of an unintentional overdose of intraviteal ganciclovir in the left eye of a man with macular atrophy secondary to Good syndrome–associated cytomegalovirus retinitis.
This case report describes how conjunctival and episcleral blood flow can be visualized using optical coherence tomography angiography.
This case report describes an unusual sequal to the implantation of an intraocular lens and describes the method used to correct it.
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