This post hoc analysis of the CLARITY randomized clinical trial investigates the distribution of neovascularization in patients with proliferative diabetic retinopathy and the topographical response of neovascularization to treatment with aflibercept or panretinal photocoagulation.
This survey study uses data from a random sample of patients from 2 tertiary eye care centers to investigate the association of missed ophthalmic appointments with patient fear of contracting the coronavirus disease 2019 virus, SARS-CoV-2.
This quality improvement study examines the institutional cost savings of a policy to diagnose adenoviral conjunctivitis and triage and furlough medical center employees with suspected adenoviral conjunctivitis to prevent outbreaks.
This cross-sectional study examines the association between vision impairment or eye disease and quality of life and the outcome of ophthalmic interventions on quality of life globally and across the life span.
This randomized clinical trial evaluates the use of intravitreal aflibercept as prophylaxis against conversion to exudative age-related macular degeneration (AMD) in patients with dry AMD and high risk for conversion.
This cross-sectional study examines the use of structural changes in the retina as biomarkers to identify amyloid-β deposition in assessment of individuals for preclinical Alzheimer disease.
This cohort study comprises phase 3 of the Ocular Hypertension Treatment Study and assesses the 20-year cumulative incidence and severity of primary open-angle glaucoma among the original cohort of participants with ocular hypertension.
This cross-sectional study compares stress during investigational optical coherence tomography imaging to that during binocular indirect ophthalmoscopy for retinopathy of prematurity.
An elderly man with a history of Philadelphia chromosome–positive acute lymphocytic leukemia, diabetes, and dementia presented with decreased visual acuity and hypopyon in his right eye. What would you do next?
A septuagenarian with a history of Crohn disease, coronary artery disease, hypercholesterolemia, and transient ischemic attack presents with sudden, painless visual loss. Examination of a temporal artery biopsy specimen shows chronic, nongranulomatous inflammation. Reexamination of the biopsy specimen 2 weeks later shows abundant transmural deposits of amorphous eosinophilic acellular material that exhibit apple-green birefringence consistent with amyloid deposits; IgM and lambda light chain restriction are also observed. What would you do next?
A 70-year-old woman presented with a history of hypertension, hyperlipidemia, and bilateral asymmetric corneal lesions. What is your diagnosis?
A 40-year-old man presents with decreased vision 3 weeks after undergoing a 2-stage Baerveldt implantation. Ocular history shows Sturge-Weber syndrome, secondary glaucoma, and chronic retinal detachment. Examination showed a red glow of the fundus with shifting subretinal fluid and retinal detachment in the left eye, and retinal detachment and demonstrated homogeneous diffuse choroidal thickening in the right eye. What would you do next?
This study examines the association of myelin oligodendrocyte glycoprotein immunoglobulin G–associated disorder with pediatric optic neuritis to guide prognosis and treatment.
These case reports investigate the potential association between BRAF inhibitors and conjunctival plaques in patients with pediatric brain tumor.
This case report describes a woman with an unusual, idiopathic epiretinal membrane visible on multiple types of imaging.