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December 2021 - January 1929

Decade

Year

Issue

September 2021, Vol 139, No. 9, Pages 933-1042

Viewpoint

Addressing Disparities in Eye Care—The Time Is Now

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):935-936. doi:10.1001/jamaophthalmol.2021.2053

This Viewpoint describes racial/ethnic disparities in eye care and suggests ways in which clinicians can begin to address them.

Original Investigation

Ophthalmic Injuries After the Port of Beirut Blast—One of Largest Nonnuclear Explosions in History

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):937-943. doi:10.1001/jamaophthalmol.2021.2742

This study reports the ocular injuries sustained by survivors of the Port of Beirut blast in Beirut, Lebanon, on August 4, 2020.

Evaluation of Intravitreal Aflibercept for the Treatment of Severe Nonproliferative Diabetic Retinopathy: Results From the PANORAMA Randomized Clinical Trial

Abstract Full Text
open access
JAMA Ophthalmol. 2021;139(9):946-955. doi:10.1001/jamaophthalmol.2021.2809

This randomized clinical trial evaluates whether treatment with intravitreal aflibercept vs sham injections results in anatomic improvement from baseline through 100 weeks in eyes with moderately severe to severe nonproliferative diabetic retinopathy and no diabetic macular edema.

SARS-CoV-2 on Ocular Surfaces in a Cohort of Patients With COVID-19 From the Lombardy Region, Italy

Abstract Full Text
free access has active quiz
JAMA Ophthalmol. 2021;139(9):956-963. doi:10.1001/jamaophthalmol.2020.5464

This cohort study investigates the presence of SARS-CoV-2 in tears collected from patients with COVID-19 by means of a reverse transcription–polymerase chain reaction assay and assesses the association of virus presence with concomitant clinical conditions.

Validation and Clinical Applicability of Whole-Volume Automated Segmentation of Optical Coherence Tomography in Retinal Disease Using Deep Learning

Abstract Full Text
open access has multimedia
JAMA Ophthalmol. 2021;139(9):964-973. doi:10.1001/jamaophthalmol.2021.2273

This diagnostic study evaluates a deep learning model for whole-volume segmentation of 4 clinically important pathological features as well as clinical applicability.

Application of 5G Technology to Conduct Real-Time Teleretinal Laser Photocoagulation for the Treatment of Diabetic Retinopathy

Abstract Full Text
open access has multimedia
JAMA Ophthalmol. 2021;139(9):975-982. doi:10.1001/jamaophthalmol.2021.2312

This study assesses the feasibility of real-time telephotocoagulation treatment for diabetic retinopathy.

Minimally Invasive Glaucoma Surgical Techniques for Open-Angle Glaucoma: An Overview of Cochrane Systematic Reviews and Network Meta-analysis

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):983-989. doi:10.1001/jamaophthalmol.2021.2351

This meta-analysis examines systematic reviews conducted by Cochrane Eyes and Vision to evaluate techniques and devices used in minimally invasive glaucoma surgeries alone or with cataract extraction.

Effect of Combined Atropine and Patching vs Patching Alone for Treatment of Severe Amblyopia in Children Aged 3 to 12 Years: A Randomized Clinical Trial

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):990-996. doi:10.1001/jamaophthalmol.2021.2413

This randomized clinical trial compares the efficacy of combined atropine and patching therapy vs patching alone in children with severe amblyopia.

Home-Use Evaluation of a Wearable Collision Warning Device for Individuals With Severe Vision Impairments: A Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2021;139(9):998-1005. doi:10.1001/jamaophthalmol.2021.2624

This randomized clinical trial evaluates the effect of a collision warning device on the number of contacts experienced by blind and visually impaired people in their daily mobility.

Efficacy of a Web App–Based Music Intervention During Cataract Surgery: A Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2021;139(9):1007-1013. doi:10.1001/jamaophthalmol.2021.2767

This randomized clinical trial describes the effects of a web app–based music intervention on the incidence of hypertension in patients during cataract surgery performed under local anesthesia.

Presumed SARS-CoV-2 Viral Particles in the Human Retina of Patients With COVID-19

Abstract Full Text
free access has active quiz
JAMA Ophthalmol. 2021;139(9):1015-1021. doi:10.1001/jamaophthalmol.2021.2795

This case series describes the presence of presumed SARS-CoV-2 viral particles in the retina of individuals who died of COVID-19.

Brief Report

Association of Monogenic and Polygenic Risk With the Prevalence of Open-Angle Glaucoma

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):1023-1028. doi:10.1001/jamaophthalmol.2021.2440

This cross-sectional study compares polygenic and monogenic variants associated with risk of glaucoma.

Clinical and Histopathologic Correlates of Asymmetric Retinitis Pigmentosa

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):1029-1032. doi:10.1001/jamaophthalmol.2021.2688

This case report evaluates whether additional information can be obtained about asymmetric RP from studying clinical imaging and pathology correlates, including pathology samples from autopsied eyes.

Invited Commentary

Ophthalmic Injuries in the Port Explosion in Beirut, Lebanon: Lessons for Provision of Ophthalmic Trauma Care and Major Incident Management

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):943-945. doi:10.1001/jamaophthalmol.2021.2707

Deep Learning–Based Automated Optical Coherence Tomography Segmentation in Clinical Routine: Getting Closer

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):973-974. doi:10.1001/jamaophthalmol.2021.2309

Patching and Atropine for Severe Amblyopia: Are Both Better Than Patching Alone?

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):996-997. doi:10.1001/jamaophthalmol.2021.2425

The Complexity of Integrating Observations Into Observational Research

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):1005-1006. doi:10.1001/jamaophthalmol.2021.2633

Masking Is Not Just for COVID-19

Abstract Full Text
JAMA Ophthalmol. 2021;139(9):1013-1014. doi:10.1001/jamaophthalmol.2021.2706

Identification of COVID-19 Virus in Human Intraocular Tissues

Abstract Full Text
free access
JAMA Ophthalmol. 2021;139(9):1021-1022. doi:10.1001/jamaophthalmol.2021.2806
JAMA Ophthalmology Clinical Challenge

Subacute Vision Loss in a 37-Year-Old Man With a Rash

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2021;139(9):1033-1034. doi:10.1001/jamaophthalmol.2020.6586

A 37-year-old man presents with subacute vision loss after experiencing malaise, low-grade fever, and a rash 2 weeks earlier. The rash persists on his scalp and extremities. What would you do next?

Bilateral Visual Acuity Loss in a 28-Year-Old Man With Duchenne Muscular Dystrophy

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2021;139(9):1035-1036. doi:10.1001/jamaophthalmol.2020.6852

A 28-year-old man with Duchenne muscular dystrophy but no ophthalmic history presents with recent visual acuity loss. What would you do next?

Split Down the Middle of the Fovea

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2021;139(9):1037-1038. doi:10.1001/jamaophthalmol.2020.6869

A woman presents with blurred vision with slight metamorphopsia in the right eye. Imaging showed hyperreflective layering on the foveal surface and splitting of the outer plexiform layer. What would you do next?

Metamorphopsia in a Middle-aged Man

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2021;139(9):1039-1040. doi:10.1001/jamaophthalmol.2020.7095

A 47-year-old man with a history of hypertension, obesity, left adrenalectomy, and pterygium excision surgery presents with gradual onset of blurry vision in both eyes for several months. What would you do next?

Ophthalmic Images

Hypoplasic Vitreous in Stickler Syndrome

Abstract Full Text
online only
JAMA Ophthalmol. 2021;139(9):e213312. doi:10.1001/jamaophthalmol.2021.3312

This case report describes a 9-year-old patient with a presumed ocular-only variant of Stickler syndrome.

Polycoria Due to Extensive Persistent Pupillary Membranes

Abstract Full Text
online only
JAMA Ophthalmol. 2021;139(9):e213320. doi:10.1001/jamaophthalmol.2021.3320

This case report describes a man in his 40s with best-corrected visual acuity of 20/20 OU who had extensive iris strands in the anterior segment of the right eye, causing multiple pupillary openings in the iris.

Comment & Response

Live and Replication-Competent SARS-CoV-2 in Ocular Fluids

Abstract Full Text
free access
JAMA Ophthalmol. 2021;139(9):1041. doi:10.1001/jamaophthalmol.2021.2681

Live and Replication-Competent SARS-CoV-2 in Ocular Fluids—Reply

Abstract Full Text
free access
JAMA Ophthalmol. 2021;139(9):1041-1042. doi:10.1001/jamaophthalmol.2021.2751
Correction

Labeling Errors in Figure

Abstract Full Text
free access
JAMA Ophthalmol. 2021;139(9):1042. doi:10.1001/jamaophthalmol.2021.2850
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2021;139(9):933. doi:10.1001/jamaophthalmol.2020.3785
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