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October 19, 2017
Original Investigation

Association of Socioeconomics With Prevalence of Visual Impairment and Blindness

Abstract Full Text
free access
JAMA Ophthalmol. Published online October 19, 2017. doi:10.1001/jamaophthalmol.2017.3449

This cross-sectional study explores correlations of the prevalence of visual impairment with socioeconomic factors at country levels and models and estimates a socioeconomic-adjusted disease burden based on these data.

Long-term Outcomes After Proton Beam Irradiation in Patients With Large Choroidal Melanomas

Abstract Full Text
JAMA Ophthalmol. Published online October 19, 2017. doi:10.1001/jamaophthalmol.2017.3805

This single-center cohort study analyzes 10-year outcomes of visual acuity, eye retention, development of neovascular glaucoma, tumor recurrence, and melanoma-related mortality in patients who underwent proton beam irradiation for large choroidal melanomas.

Optical Coherence Tomography Angiography for Assessment of the 3-Dimensional Structures of Polypoidal Choroidal Vasculopathy

Abstract Full Text
JAMA Ophthalmol. Published online October 19, 2017. doi:10.1001/jamaophthalmol.2017.4360

This cohort study assesses the use of 3-dimensional imaging by means of optical coherence tomography angiography to show polypoidal complexes in patients with polypoidal choroidal vasculopathy.

Invited Commentary

The Role of Optical Coherence Tomography Angiography in Polypoidal Choroidal Vasculopathy

Abstract Full Text
JAMA Ophthalmol. Published online October 19, 2017. doi:10.1001/jamaophthalmol.2017.4453
JAMA Ophthalmology Clinical Challenge

Acute Bilateral Eyelid Edema in a 3-Year-Old Girl With Pyuria

Abstract Full Text
JAMA Ophthalmol. Published online October 19, 2017. doi:10.1001/jamaophthalmol.2017.2978

A 3-year-old girl presented to the emergency department with high fever, bilateral upper and lower eyelid edema, and pyuria; the patient returned 2 days later with persistent fever, worsening eyelid edema, and a new macular rash over her buttocks and shins. What would you do next?

Observation

A Case of Unexpected Adult-Onset Neurologic Decline in CLN3-Associated Retinal Degeneration

Abstract Full Text
JAMA Ophthalmol. Published online October 19, 2017. doi:10.1001/jamaophthalmol.2017.4353

This case report describes a young man with a mutation in CLN3 who developed progressive retinal degeneration and neurologic dysfunction.

Comment & Response

Association of Endogenous Endophthalmitis With Intravenous Drug UseAn Emerging Public Health Challenge

Abstract Full Text
JAMA Ophthalmol. Published online October 19, 2017. doi:10.1001/jamaophthalmol.2017.4342

Endogenous Endophthalmitis Associated With Intravenous Drug Use—Reply

Abstract Full Text
JAMA Ophthalmol. Published online October 19, 2017. doi:10.1001/jamaophthalmol.2017.4357
October 12, 2017
Original Investigation

Potential of Aqueous Humor as a Surrogate Tumor Biopsy for Retinoblastoma

Abstract Full Text
JAMA Ophthalmol. Published online October 12, 2017. doi:10.1001/jamaophthalmol.2017.4097

This case series study investigates whether the aqueous humor of retinoblastoma eyes has sufficient tumor-derived DNA to perform genetic analysis of the tumor, including DNA copy number alterations.

Progression of Stargardt Disease as Determined by Fundus Autofluorescence in the Retrospective Progression of Stargardt Disease Study (ProgStar Report No. 9)

Abstract Full Text
JAMA Ophthalmol. Published online October 12, 2017. doi:10.1001/jamaophthalmol.2017.4152

This multicenter cohort study describes the yearly progression rate of atrophic lesions as determined by fundus autofluorescence in the retrospective Progression of Stargardt Disease study.

Prevalence of Age-Related Macular Degeneration in AustraliaThe Australian National Eye Health Survey

Abstract Full Text
JAMA Ophthalmol. Published online October 12, 2017. doi:10.1001/jamaophthalmol.2017.4182

This study examines the prevalence of age-related macular degeneration in Australia.

Time Requirements for Electronic Health Record Use in an Academic Ophthalmology Center

Abstract Full Text
JAMA Ophthalmol. Published online October 12, 2017. doi:10.1001/jamaophthalmol.2017.4187

This single-center cohort study examines ophthalmologist time requirements for electronic health record use.

Invited Commentary

How Much Time Should We Be Spending With Electronic Health Records?

Abstract Full Text
JAMA Ophthalmol. Published online October 12, 2017. doi:10.1001/jamaophthalmol.2017.3517

Liquid Biopsy in Retinoblastoma

Abstract Full Text
JAMA Ophthalmol. Published online October 12, 2017. doi:10.1001/jamaophthalmol.2017.4094
JAMA Ophthalmology Clinical Challenge

Abnormal Magnetic Resonance Imaging Findings in a Patient With Optic Disc Edema, Retinal Hemorrhage, and Decreased Vision

Abstract Full Text
JAMA Ophthalmol. Published online October 12, 2017. doi:10.1001/jamaophthalmol.2017.3003

A woman in her 30s was referred for evaluation of severe bilateral optic disc edema, retinal hemorrhages, and a gradual decrease in vision during a 3-week period. What would you do next?

October 9, 2017
Editorial

Death by Gun Violence—A Public Health Crisis

Abstract Full Text
free access
JAMA Ophthalmol. Published online October 9, 2017. doi:10.1001/jamaophthalmol.2017.5180
October 5, 2017
Original Investigation

Choriocapillaris Imaging Using Multiple En Face Optical Coherence Tomography Angiography Image Averaging

Abstract Full Text
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JAMA Ophthalmol. Published online October 5, 2017. doi:10.1001/jamaophthalmol.2017.3904

This cross-sectional case series investigates multiple en face image averaging for optical coherence tomography angiography images of the choriocapillaris.

Efficacy and Safety of Ranibizumab With or Without Verteporfin Photodynamic Therapy for Polypoidal Choroidal VasculopathyA Randomized Clinical Trial

Abstract Full Text
open access
JAMA Ophthalmol. Published online October 5, 2017. doi:10.1001/jamaophthalmol.2017.4030

This randomized clinical trial compares the efficacy and safety of combination therapy of ranibizumab and verteporfin photodynamic therapy with ranibizumab monotherapy in polypoidal choroidal vasculopathy.

Association Between Opioid Prescribing Patterns and Abuse in Ophthalmology

Abstract Full Text
JAMA Ophthalmol. Published online October 5, 2017. doi:10.1001/jamaophthalmol.2017.4055

This observational cohort study determines the opioid prescribing patterns among ophthalmologists and elucidates ophthalmologists’ role in the prescription opioid abuse epidemic.

Invited Commentary

Adopting the Results of Everest II Into PracticeA Clearer View From a Higher Level Study

Abstract Full Text
JAMA Ophthalmol. Published online October 5, 2017. doi:10.1001/jamaophthalmol.2017.3118

Image Averaging, a Powerful Tool in Optical Coherence Tomography and OCT Angiography

Abstract Full Text
JAMA Ophthalmol. Published online October 5, 2017. doi:10.1001/jamaophthalmol.2017.4015
JAMA Ophthalmology Clinical Challenge

Retina Folds and Subretinal Fluid After Bell Palsy

Abstract Full Text
JAMA Ophthalmol. Published online October 5, 2017. doi:10.1001/jamaophthalmol.2017.2778

A woman in her late 20s presented with blurry vision in both eyes. A dilated ophthalmoscopic examination revealed mild optic nerve pallor and bilateral serous macular detachment. What would you do next?

Observation

Ischemic Retinal Vascular Disease in an Infant With Hemophagocytic Lymphohistiocytosis

Abstract Full Text
JAMA Ophthalmol. Published online October 5, 2017. doi:10.1001/jamaophthalmol.2017.3258

This case report is about the ophthalmic manifestations of hemophagocytic lymphohistiocytosis, a rare and often fatal disease commonly seen in infants.

Comment & Response

Risk of Intraocular Bleeding and the New Anticoagulants: Not Such a Big Effect

Abstract Full Text
JAMA Ophthalmol. Published online October 5, 2017. doi:10.1001/jamaophthalmol.2017.4021

Risk of Intraocular Bleeding and the New Anticoagulants: Not Such a Big Effect—Reply

Abstract Full Text
JAMA Ophthalmol. Published online October 5, 2017. doi:10.1001/jamaophthalmol.2017.4024
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