This randomized clinical trial evaluates the efficacy of administration of an adeno-associated virus vector designed to deliver a functional version of the CHM gene in patients with choroideremia.
This randomized clinical trial compares the clinical effectiveness of intravitreal therapy with ranibizumab vs aflibercept vs bevacizumab for the management of macular edema secondary to central retinal vein occlusion.
This study identifies and characterizes outcomes specified in ClinicalTrials.gov records for publicly funded clinical trials for 3 high-burden, high-prevalence eye conditions.
A 53-year-old man presents with a bulging left eye, several eyeglass prescription changes in the left eye over the past 2 years, and frequent ipsilateral tearing. What would you do next?
This cross-sectional study assesses the quality, content, and readability of diabetic retinopathy information found online.
This cross-sectional study investigates if a genetic risk score that comprised 12 primary open-angle glaucoma genetic risk variants is associated with age at disease diagnosis.
A 25-year-old man presented to the emergency department with rapidly decreased visual acuity and exceptionally high intraocular pressure in both eyes. What would you do next?
This bibliometric analysis explores sex distributions in ophthalmic research by evaluating the representation of female authorships.
This cross-sectional study examines the current prevalence rate of myopia and the association between environmental factors and myopia in Japanese schoolchildren.
This observational study examines whether peripapillary retinal thickness measures obtained during head-down tilted bed rest with carbon dioxide, 0.5%, exposure are associated with B vitamin status and single-nucleotide polymorphisms involved in 1-carbon metabolism pathways.
An 81-year-old man presents with a gradual decline in his vision bilaterally over 2 years and a chronic cough. What would you do next?
This case series describes the characteristics of acute retinopathy and fundus changes among patients with pseudoxanthoma elasticum.
This cohort study examines the incidence of biopsy-proven giant cell arteritis in a tertiary care center–based population with a sizeable proportion of black patients.
This cross-sectional study compares the diagnostic accuracy of a smartphone-based artificial intelligence system vs ophthalmologist judgement in patients with referable diabetic retinopathy or any diabetic retinopathy in Mumbai, India.
A 79-year-old woman presented to the eye emergency department with right eye pain and photophobia after Descemet stripping automated endothelial keratoplasty. What would you do next?
This cohort study estimates the progression rate of atrophic lesions over a 12-month period in the eyes of individuals with Stargardt disease.
This cohort study examines the use of yellow-lens glasses for detection of pedestrians during night driving by younger and older individuals.
This qualitative evaluation investigates the financial and environmental costs of unused pharmaceutical products after phacoemulsification surgery among US surgical sites.
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