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Year

Day

August 29, 2019
Original Investigation

Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients With Choroideremia: A Randomized Clinical Trial

Abstract Full Text
JAMA Ophthalmol. Published online August 29, 2019. doi:10.1001/jamaophthalmol.2019.3278

This randomized clinical trial evaluates the efficacy of administration of an adeno-associated virus vector designed to deliver a functional version of the CHM gene in patients with choroideremia.

Clinical Effectiveness of Intravitreal Therapy With Ranibizumab vs Aflibercept vs Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion: A Randomized Clinical Trial

Abstract Full Text
open access
JAMA Ophthalmol. Published online August 29, 2019. doi:10.1001/jamaophthalmol.2019.3305

This randomized clinical trial compares the clinical effectiveness of intravitreal therapy with ranibizumab vs aflibercept vs bevacizumab for the management of macular edema secondary to central retinal vein occlusion.

Brief Report

Outcome Specification in a Sample of Publicly Funded Eye and Vision Trials Registered on ClinicalTrials.gov

Abstract Full Text
JAMA Ophthalmol. Published online August 29, 2019. doi:10.1001/jamaophthalmol.2019.3289

This study identifies and characterizes outcomes specified in ClinicalTrials.gov records for publicly funded clinical trials for 3 high-burden, high-prevalence eye conditions.

Invited Commentary

Gene Therapy for Choroideremia—Progress and Remaining Questions

Abstract Full Text
JAMA Ophthalmol. Published online August 29, 2019. doi:10.1001/jamaophthalmol.2019.3295
JAMA Ophthalmology Clinical Challenge

Uncovered Undulations

Abstract Full Text
has active quiz
JAMA Ophthalmol. Published online August 29, 2019. doi:10.1001/jamaophthalmol.2019.3090

A 53-year-old man presents with a bulging left eye, several eyeglass prescription changes in the left eye over the past 2 years, and frequent ipsilateral tearing. What would you do next?

Comment & Response

Lamina Cribrosa Pore Diameter and Spaceflight-Associated Neuro-ocular Syndrome

Abstract Full Text
JAMA Ophthalmol. Published online August 29, 2019. doi:10.1001/jamaophthalmol.2019.3319

Lamina Cribrosa Pore Diameter and Spaceflight-Associated Neuro-ocular Syndrome—Reply

Abstract Full Text
JAMA Ophthalmol. Published online August 29, 2019. doi:10.1001/jamaophthalmol.2019.3322
Correction

Errors in Abstract, Text, and Figure

Abstract Full Text
free access
JAMA Ophthalmol. Published online August 29, 2019. doi:10.1001/jamaophthalmol.2019.3583
August 22, 2019
Original Investigation

Assessment of the Quality, Content, and Readability of Freely Available Online Information for Patients Regarding Diabetic Retinopathy

Abstract Full Text
JAMA Ophthalmol. Published online August 22, 2019. doi:10.1001/jamaophthalmol.2019.3116

This cross-sectional study assesses the quality, content, and readability of diabetic retinopathy information found online.

Brief Report

Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis

Abstract Full Text
JAMA Ophthalmol. Published online August 22, 2019. doi:10.1001/jamaophthalmol.2019.3109

This cross-sectional study investigates if a genetic risk score that comprised 12 primary open-angle glaucoma genetic risk variants is associated with age at disease diagnosis.

Invited Commentary

Online Information for Diabetic Retinopathy—Often a Missed Opportunity for Patient Education

Abstract Full Text
JAMA Ophthalmol. Published online August 22, 2019. doi:10.1001/jamaophthalmol.2019.3146
JAMA Ophthalmology Clinical Challenge

Acute Onset of Blurry Vision in a Young Man

Abstract Full Text
has active quiz
JAMA Ophthalmol. Published online August 22, 2019. doi:10.1001/jamaophthalmol.2019.3058

A 25-year-old man presented to the emergency department with rapidly decreased visual acuity and exceptionally high intraocular pressure in both eyes. What would you do next?

Comment & Response

Emphasizing Optimal Diabetes Management for All Races/Ethnicities, but Not Race/Ethnicity–Specific Cut Points for Hemoglobin A1c

Abstract Full Text
JAMA Ophthalmol. Published online August 22, 2019. doi:10.1001/jamaophthalmol.2019.3230

Emphasizing Optimal Diabetes Management for All Races/Ethnicities, but Not Race/Ethnicity–Specific Cut Points for Hemoglobin A1c

Abstract Full Text
JAMA Ophthalmol. Published online August 22, 2019. doi:10.1001/jamaophthalmol.2019.3233
August 15, 2019
Original Investigation

Sex Disparities in Ophthalmic Research: A Descriptive Bibliometric Study on Scientific Authorships

Abstract Full Text
JAMA Ophthalmol. Published online August 15, 2019. doi:10.1001/jamaophthalmol.2019.3095

This bibliometric analysis explores sex distributions in ophthalmic research by evaluating the representation of female authorships.

Current Prevalence of Myopia and Association of Myopia With Environmental Factors Among Schoolchildren in Japan

Abstract Full Text
JAMA Ophthalmol. Published online August 15, 2019. doi:10.1001/jamaophthalmol.2019.3103

This cross-sectional study examines the current prevalence rate of myopia and the association between environmental factors and myopia in Japanese schoolchildren.

Brief Report

Association of Genetics and B Vitamin Status With the Magnitude of Optic Disc Edema During 30-Day Strict Head-Down Tilt Bed Rest

Abstract Full Text
JAMA Ophthalmol. Published online August 15, 2019. doi:10.1001/jamaophthalmol.2019.3124

This observational study examines whether peripapillary retinal thickness measures obtained during head-down tilted bed rest with carbon dioxide, 0.5%, exposure are associated with B vitamin status and single-nucleotide polymorphisms involved in 1-carbon metabolism pathways.

Invited Commentary

The Glass Ceiling in Ophthalmology—Next Comes How to Change This

Abstract Full Text
JAMA Ophthalmol. Published online August 15, 2019. doi:10.1001/jamaophthalmol.2019.3113
JAMA Ophthalmology Clinical Challenge

An 81-Year-Old Man With Multifocal Choroidal Lesions

Abstract Full Text
has active quiz
JAMA Ophthalmol. Published online August 15, 2019. doi:10.1001/jamaophthalmol.2019.3054

An 81-year-old man presents with a gradual decline in his vision bilaterally over 2 years and a chronic cough. What would you do next?

August 8, 2019
Original Investigation

Acute Retinopathy in Pseudoxanthoma Elasticum

Abstract Full Text
JAMA Ophthalmol. Published online August 8, 2019. doi:10.1001/jamaophthalmol.2019.2910

This case series describes the characteristics of acute retinopathy and fundus changes among patients with pseudoxanthoma elasticum.

Association of Giant Cell Arteritis With Race

Abstract Full Text
JAMA Ophthalmol. Published online August 8, 2019. doi:10.1001/jamaophthalmol.2019.2919

This cohort study examines the incidence of biopsy-proven giant cell arteritis in a tertiary care center–based population with a sizeable proportion of black patients.

Diagnostic Accuracy of Community-Based Diabetic Retinopathy Screening With an Offline Artificial Intelligence System on a Smartphone

Abstract Full Text
open access
JAMA Ophthalmol. Published online August 8, 2019. doi:10.1001/jamaophthalmol.2019.2923

This cross-sectional study compares the diagnostic accuracy of a smartphone-based artificial intelligence system vs ophthalmologist judgement in patients with referable diabetic retinopathy or any diabetic retinopathy in Mumbai, India.

Invited Commentary

Potentially Novel Acute Retinopathy Similar to Multiple Evanescent White Dot Syndrome in Patients With Pseudoxanthoma Elasticum

Abstract Full Text
JAMA Ophthalmol. Published online August 8, 2019. doi:10.1001/jamaophthalmol.2019.2884

Giant Cell Arteritis in Black Patients: Do We Know How Rare It Is?

Abstract Full Text
JAMA Ophthalmol. Published online August 8, 2019. doi:10.1001/jamaophthalmol.2019.2933

Smartphone-Based, Artificial Intelligence–Enabled Diabetic Retinopathy Screening

Abstract Full Text
JAMA Ophthalmol. Published online August 8, 2019. doi:10.1001/jamaophthalmol.2019.2883
JAMA Ophthalmology Clinical Challenge

Interface Haze After Descemet Stripping Automated Endothelial Keratoplasty

Abstract Full Text
has active quiz
JAMA Ophthalmol. Published online August 8, 2019. doi:10.1001/jamaophthalmol.2019.2745

A 79-year-old woman presented to the eye emergency department with right eye pain and photophobia after Descemet stripping automated endothelial keratoplasty. What would you do next?

August 1, 2019
Original Investigation

Progression of Stargardt Disease as Determined by Fundus Autofluorescence Over a 12-Month Period: ProgStar Report No. 11

Abstract Full Text
has audio
JAMA Ophthalmol. Published online August 1, 2019. doi:10.1001/jamaophthalmol.2019.2885

This cohort study estimates the progression rate of atrophic lesions over a 12-month period in the eyes of individuals with Stargardt disease.

Comparison of Pedestrian Detection With and Without Yellow-Lens Glasses During Simulated Night Driving With and Without Headlight Glare

Abstract Full Text
JAMA Ophthalmol. Published online August 1, 2019. doi:10.1001/jamaophthalmol.2019.2893

This cohort study examines the use of yellow-lens glasses for detection of pedestrians during night driving by younger and older individuals.

Quantification of the Cost and Potential Environmental Effects of Unused Pharmaceutical Products in Cataract Surgery

Abstract Full Text
JAMA Ophthalmol. Published online August 1, 2019. doi:10.1001/jamaophthalmol.2019.2901

This qualitative evaluation investigates the financial and environmental costs of unused pharmaceutical products after phacoemulsification surgery among US surgical sites.

Invited Commentary

Toward a Treatment Trial for Stargardt Disease: Putting Out the Fire

Abstract Full Text
JAMA Ophthalmol. Published online August 1, 2019. doi:10.1001/jamaophthalmol.2019.2930

Why Don’t Yellow Night Vision Glasses Work?

Abstract Full Text
JAMA Ophthalmol. Published online August 1, 2019. doi:10.1001/jamaophthalmol.2019.2907

Challenging Considerations Regarding Waste and Potential Environmental Effects in Cataract Surgery

Abstract Full Text
JAMA Ophthalmol. Published online August 1, 2019. doi:10.1001/jamaophthalmol.2019.2936
Comment & Response

Considering Same-Day Access vs Emergency Department Ophthalmic Visits in Ophthalmology Trainee Education

Abstract Full Text
JAMA Ophthalmol. Published online August 1, 2019. doi:10.1001/jamaophthalmol.2019.2939

Considering Same-Day Access vs Emergency Department Ophthalmic Visits in Ophthalmology Trainee Education—Reply

Abstract Full Text
JAMA Ophthalmol. Published online August 1, 2019. doi:10.1001/jamaophthalmol.2019.2942
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