Author Affiliations: Department of Otolaryngology, Eastern Virginia Medical School (Drs Wiles and Moody Antonio), and Department of Neurosurgery, Children's Hospital of the King's Daughters (Dr Dilustro), Norfolk, Virginia. Dr Wiles is now with the Department of Pathology, Virginia Commonwealth University, Richmond.
Giant cell reparative granuloma (GCRG), which is an uncommon, benign, granulomatous lesion of bone, was first described by Jaffe1 in 1953. It is most commonly found in the mandible but has been reported to occur in many other sites, including the axial skeleton, orbit, sinuses, and cranial vault.1,2 Approximately 35 cases of GCRG originating in the temporal bone have been reported. The lesion has been described in patients ranging in age from 2 months to 72 years.2 The youngest documented patient to date presented with a small palpable mass at the age of 2 months.3 To our knowledge, there are no previous reports of a congenital lesion. Our patient presented with a 4 × 4-cm mass at the age of 5 days, suggesting that the lesion had developed in utero.
Wiles AB, Dilustro JF, Moody Antonio SA. Congenital Giant Cell Granuloma of the Temporal Bone. Arch Otolaryngol Head Neck Surg. 2011;137(9):942–946. doi:10.1001/archoto.2011.145
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: