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Clinical Problem Solving: Pathology
Apr 2012

Pathology Quiz Case 1: Diagnosis

Arch Otolaryngol Head Neck Surg. 2012;138(4):427-428. doi:10.1001/archoto.2011.1257b

Diagnosis: Allergic fungal rhinosinusitis (AFRS)

Allergic fungal rhinosinusitis, which is a noninvasive form of chronic rhinosinusitis caused by fungi, was first described in 1976 in a patient with allergic bronchopulmonary aspergillosis.1 Initially, it was thought to be a component of allergic bronchopulmonary aspergillosis; however, in 1989, a review of surgical specimens from patients with chronic rhinosinusitis revealed that it is a distinct entity.2