IT HAS been demonstrated amply that cortisone is of value in the management of allergic disease. The great wave of enthusiasm which followed the initial reports of its use in rheumatoid arthritis and bronchial asthma has, to a great extent, waned; one no longer expects miraculous cures. However, with increasing use of this potent hormone a stage is rapidly being reached wherein definite indications for its use are becoming readily apparent. Furthermore, very definite limitations in its application are becoming obvious.
Among the gratifying results obtained with cortisone have been those in conditions in which its local use is possible. In such disorders the dose of the medication is small, and the need for repeated and continuous therapy is usually absent. The danger of severe complications from the use of the drug, therefore, is for the most part obviated. Thus, the use of cortisone in the treatment of severe allergic
JOHN W. WALL, NORMAN SHURE. INTRANASAL CORTISONEPreliminary Study. AMA Arch Otolaryngol. 1952;56(2):172–176. doi:10.1001/archotol.1952.00710020191009