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Clinical Problem Solving: Pathology
May 2012

Pathology Quiz Case 1

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2012;138(5):521. doi:10.1001/archoto.2012.79a

A 41-year-old man presented with a several-month history of symptoms that included voice change and a globus sensation in his throat. He had used tobacco, alcohol, and betel nuts for more than 10 years. His medical and family histories were otherwise unremarkable. Flexible nasopharyngoscopy revealed a supraglottic mass encroaching the ipsilateral false vocal fold and aryepiglottic fold on the right side (Figure 1). The mobility of the bilateral vocal folds was normal. No palpable cervical lymphadenopathy was detected. A chest plain film did not reveal any mass or infiltrate. The biochemical and hematologic profiles showed no abnormalities. A computed tomographic scan of the head, neck, and chest with contrast demonstrated a well-defined 1.5 × 1.5-cm mass in the right supraglottis, without involvement of the bilateral vocal folds. There was no evidence of cervical lymphadenopathy or a synchronous pulmonary tumor. Positron emission tomography revealed no distant metastases.