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Clinical Problem Solving: Radiology
Sep 2012

Radiology Quiz Case 2: Diagnosis

Arch Otolaryngol Head Neck Surg. 2012;138(9):870. doi:10.1001/archotol.138.9.870

Diagnosis: Docetaxel (Taxotere)-induced photosensitivity

Docetaxel is a well-established antimitotic chemotherapy agent that is used in the treatment of breast, colorectal, lung, ovarian, prostate, liver, renal, gastric, head and neck cancers and melanoma.1-3 It has many known adverse effects, with some of the most common including anemia, neutropenia, thrombocytopenia, constipation, fatigue, nausea, diarrhea, edema, stomatitis, nail disorders, skin lesions, and alopecia.4-6 Photosensitivity is a much rarer reaction to docetaxel.6