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Comment & Response
October 2013

No Difference in Blood Loss During Endoscopic Sinus Surgery With Total Intravenous Anesthesia—Reply

Author Affiliations
  • 1Department of Surgery, Section of Otolaryngology–Head and Neck Surgery, University of Chicago Medical Center, Chicago, Illinois
  • 2Department of Anesthesia and Critical Care, University of Chicago Medical Center, Chicago, Illinois
JAMA Otolaryngol Head Neck Surg. 2013;139(10):1077-1078. doi:10.1001/jamaoto.2013.5047

In Reply We thank you for your interest in our published article.

Regarding the anesthetic technique, the difference between the 2 groups in the mean dose of fentanyl during maintenance was not significant (P = .75 with 235 µg in one and 225 µg in the other). It is widely accepted in the anesthesia community for induction dosing of 1 to 2 mg/kg and maintenance dosing in a total intravenous anesthesia (TIVA) setting of 150 to 250 µg/kg/min.

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