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Original Articles
March 1961

Vocal Rehabilitation of Paralytic Dysphonia: VI. Further Studies of Intracordal Injection Materials

Arch Otolaryngol. 1961;73(3):290-294. doi:10.1001/archotol.1961.00740020298007

The Problem  In previous papers1-5 the established method of intracordal injection for the functional relief of laryngeal hemiparalysis was discussed. The main problem was to find a suitable substance with the following properties: (1) it must be well tolerated by the tissues; (2) it must not be resorbed in time; and (3) it must be finely dispersed in a harmless vehicle in order to be injectable through the long needle of the Bruenings syringe.1Perusal of the literature7,16,19,21 shows that many substances have been recommended as implantation materials for the correction of deformities or tissue defects. Cartilage and bone, obtained and prepared in various manners,8-11,14,17-18,20,22 have been most widely used. It seemed, therefore, logical to begin our experiments with finely ground cartilage particles suspended in sterile gelatin.After sufficient experience was gained with animal experiments,1 a series of patients were treated by means of intracordal