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Original Articles
June 1961

Steroids in Office Practice

Arch Otolaryngol. 1961;73(6):689-697. doi:10.1001/archotol.1961.00740020703014

The purpose of this presentation is to review some of the basic guiding principles of steroid therapy. As an endocrinologist I would feel it presumptuous of me to spell out the detailed steroid management of each and every otolaryngological and ophthalmological disease. However, if I can help guide you through the maze of new steroid compounds currently available, and leave you with a few basic concepts concerning the use of steroids applicable to any field of medicine, I hope that this will provide a

small contribution to your annual midwinter meeting.

Some Definitions  Steroids are derivatives of the hydrocarbon, cyclopentanoperhydrophenanthrene (Fig. 1). This chemical nucleus consists of 4 rings and 17 carbon atoms. All of the naturally occurring gonadal and adrenal cortical hormones are steroid compounds. The term "steroids," employed in the title of this paper, actually refers to a specific group of steroid compounds known as corticosteroids. Corticosteroids (corticoids)

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