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Original Articles
June 1961

Embryonal Rhabdomyosarcoma: Three Case Reports with Primary Presentation in the Ear and on the Neck

Arch Otolaryngol. 1961;73(6):705-709. doi:10.1001/archotol.1961.00740020719016

In 1950, Stobbe and Dargeon6 alerted otolaryngologists and pathologists about a rare group of tumors in the head and neck area occurring in early childhood and up through adolescence, which they called "embryonal rhabdomyosarcomas." Since then, a large series of 37 cases has been studied by Moore and Grossi.5 These authors stated that the embryonal rhabdomyosarcomas are radiosensitive in almost every instance. Areán and Marcial-Rojas1 reported a case of a newborn infant with embryonal rhabdomyoscarcoma of the floor of the mouth. Blanchard and House2 reported 2 cases with primary presentation in the ear. Of 39 cases of rhabdomyosarcomas reported by Horn and Enterline,3 there were 13 cases of the embryonal type, 7 of which involved the head and neck area. In Brazil, Luisi and Andrade4 have reported a partially differentiated rhabdomyosarcoma of the nasal cavity in a 12-year-old girl.

These tumors are rarely recognized